Journal article
Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation.
Abstract
The increase in thickness of bronchial walls by such structural changes as subepithelial fibrosis contributes to the severity and chronicity of asthma by amplifying airway narrowing. However, the pathogenesis of this structural alteration is not known. Transforming growth factor beta 1 (TGF beta 1) is known to have biologic activities relevant to the cellular and molecular events in subepithelial fibrosis, such as the deposition of collagen I …
Authors
Ohno I; Nitta Y; Yamauchi K; Hoshi H; Honma M; Woolley K; O'Byrne P; Tamura G; Jordana M; Shirato K
Journal
American Journal of Respiratory Cell and Molecular Biology, Vol. 15, No. 3, pp. 404–409
Publisher
American Thoracic Society
Publication Date
September 1996
DOI
10.1165/ajrcmb.15.3.8810646
ISSN
1044-1549