Journal article
Prostaglandin F2α increases responsiveness of pulmonary airways in dogs
Abstract
We studied the effect of prostaglandin F2 alpha (PGF2 alpha) on the responsiveness of pulmonary airways in dogs. Airway responsiveness was assessed by determining the bronchoconstrictor response to increasing concentrations of acetylcholine aerosol delivered to the airways. In each of five dogs, we determined responsiveness during treatment with physiologic saline, histamine, or PGF2 alpha aerosols. The doses of histamine and PGF2 alpha were …
Authors
O'Byrne PM; Aizawa H; Bethel RA; Chung KF; Nadel JA; Holtzman MJ
Journal
Prostaglandins, Vol. 28, No. 4, pp. 537–543
Publisher
Elsevier
Publication Date
October 1984
DOI
10.1016/0090-6980(84)90242-9
ISSN
0090-6980