Journal article
Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial
Abstract
BACKGROUND: Although inhaled glucocorticosteroids are recommended for persistent asthma, their long-term effect on recent onset, mild, persistent asthma has yet to be established.
METHODS: We did a randomised, double-blind clinical trial in 7241 patients in 32 countries to assess the effects of budesonide in patients who had had mild persistent asthma for less than 2 years and who had not had previous regular treatment with …
Authors
Pauwels RA; Pedersen S; Busse WW; Tan WC; Chen Y-Z; Ohlsson SV; Ullman A; Lamm CJ; O'Byrne PM; Group OBOTSI
Journal
The Lancet, Vol. 361, No. 9363, pp. 1071–1076
Publisher
Elsevier
Publication Date
3 2003
DOI
10.1016/s0140-6736(03)12891-7
ISSN
0140-6736
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Administration, TopicalAdolescentAdultAgedAnti-Asthmatic AgentsAnti-Inflammatory AgentsAsthmaBody HeightBronchodilator AgentsBudesonideChildChild, PreschoolDose-Response Relationship, DrugDouble-Blind MethodDrug Therapy, CombinationFemaleForced Expiratory VolumeGlucocorticoidsHumansLong-Term CareMaleMiddle AgedNebulizers and Vaporizers