Journal article
Lung Homing of Endothelial Progenitor Cells in Humans with Asthma after Allergen Challenge
Abstract
RATIONALE: Increased bronchial vascularity is a feature of asthma that can contribute to airflow obstruction and progressive decline in lung function. Angiogenesis is associated with the lung homing and in situ differentiation of endothelial progenitor cells (EPC) in mouse models of asthma. We have previously shown that inhibiting allergen (Ag)-induced recruitment of EPC in sensitized mice attenuated increased bronchial vascularity and …
Authors
Imaoka H; Punia N; Irshad A; Ying S; Corrigan CJ; Howie K; O'Byrne PM; Gauvreau GM; Sehmi R
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 184, No. 7, pp. 771–778
Publisher
American Thoracic Society
Publication Date
October 1, 2011
DOI
10.1164/rccm.201102-0272oc
ISSN
1073-449X