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The Safety of Long-Acting β-Agonists among...
Journal article

The Safety of Long-Acting β-Agonists among Patients with Asthma Using Inhaled Corticosteroids

Abstract

RATIONALE: Inhaled long-acting beta-agonists (LABAs), when used as monotherapy in asthma, may increase asthma-related hospitalizations, life threatening events requiring intubation/mechanical ventilation, and asthma-related deaths, but concomitant use of inhaled corticosteroids (ICS) may modify this effect. OBJECTIVES: To determine the safety of long-acting beta-agonists among patients with asthma using corticosteroids.

Authors

Jaeschke R; O'Byrne PM; Mejza F; Nair P; Lesniak W; Brozek J; Thabane L; Cheng J; Schünemann HJ; Sears MR

Journal

American Journal of Respiratory and Critical Care Medicine, Vol. 178, No. 10, pp. 1009–1016

Publisher

American Thoracic Society

Publication Date

November 15, 2008

DOI

10.1164/rccm.200804-494oc

ISSN

1073-449X