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Effect of Inhaled Formoterol and Budesonide on...
Journal article

Effect of Inhaled Formoterol and Budesonide on Exacerbations of Asthma

Abstract

BACKGROUND: The role of long-acting, inhaled beta2-agonists in treating asthma is uncertain. In a double-blind study, we evaluated the effects of adding inhaled formoterol to both lower and higher doses of the inhaled glucocorticoid budesonide. METHODS: After a four-week run-in period of treatment with budesonide (800 microg twice daily), 852 patients being treated with glucocorticoids were randomly assigned to one of four treatments given …

Authors

Pauwels RA; Löfdahl C-G; Postma DS; Tattersfield AE; O'Byrne P; Barnes PJ; Ullman A

Journal

New England Journal of Medicine, Vol. 337, No. 20, pp. 1405–1411

Publisher

Massachusetts Medical Society

Publication Date

November 13, 1997

DOI

10.1056/nejm199711133372001

ISSN

0028-4793