Blood Coagulation
Concept
Vocabulary Service
Overview
subject area of
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2 Mechanisms of action of low molecular weight heparins and heparinoids Journal Articles
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2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis Journal Articles
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2021 Update of the International Council for Standardization in Haematology Recommendations for Laboratory Measurement of Direct Oral Anticoagulants Journal Articles
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4D intravital imaging identifies platelets as the predominant cellular procoagulant surface in a mouse hemostasis model Journal Articles
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A Control Switch for Prothrombinase Journal Articles
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A Low Molecular Weight Heparin Alters the Fetal Coagulation System in the Pregnant Sheep Journal Articles
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A National Canadian Survey of Antithrombotic Therapy After Urgent and Emergent Limb Revascularization Journal Articles
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A New, Simplified Measure of Anticoagulation Control With Warfarin: Potential Role in the Direct Oral Anticoagulant Era Journal Articles
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A Protease TAMER: a nucleic acid‐based anticoagulant Journal Articles
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A Step Change in Oral Anticoagulation: Lack of Coagulation Monitoring with Ximelagatran Journal Articles
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A decisional model to individualize warfarin recommendations: Expected impact on treatment and outcome rates in a real-world population with atrial fibrillation Journal Articles
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A non-anticoagulant synthetic pentasaccharide reduces inflammation in a murine model of kidney ischemia-reperfusion injury Journal Articles
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A novel antithrombotic coronary stent: lysine-poly(HEMA)-modified cobalt–chromium stent with fibrinolytic activity Journal Articles
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A novel congenital haemostatic defect Journal Articles
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A prospective study of an aggressive warfarin dosing algorithm to reach and maintain INR 2 to 3 after heart valve surgery Journal Articles
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A specific fluorescence resonance energy quenching–based biosensor for measuring thrombin activity in whole blood Journal Articles
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AB023, A Novel Antibody That Binds Factor XI and Blocks Its Activation by Factor XIIa Journal Articles
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Accumulation of Tissue Factor into Developing Thrombi In Vivo Is Dependent upon Microparticle P-Selectin Glycoprotein Ligand 1 and Platelet P-Selectin Journal Articles
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Activated Clotting Time to Guide Heparin Dosing in Non–ST-Segment–Elevation Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention and Treated With IIb/IIIa Inhibitors Journal Articles
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Activation of blood coagulation by plaque rupture: Mechanisms and prevention Journal Articles
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Activation of factor V during intrinsic and extrinsic coagulation. Inhibition by heparin, hirudin and d-Phe-Pro-Arg-Ch2Cl Journal Articles
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Acute coronary syndromes: a focus on thrombin. Journal Articles
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Acute phase treatment of VTE: Anticoagulation, including non-vitamin K antagonist oral anticoagulants Journal Articles
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Addition of a sequence from α2-antiplasmin transforms human serum albumin into a blood clot component that speeds clot lysis Journal Articles
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Adsorption of plasma proteins in solution to uncharged, hydrophobic polymer surfaces Journal Articles
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Advantages and limitations of the new anticoagulants Journal Articles
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Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor Journal Articles
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Altered regulation of in-vivo coagulation in orthopedic patients prior to knee or hip replacement surgery Journal Articles
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An anticoagulant dermatan sulfate proteoglycan circulates in the pregnant woman and her fetus. Journal Articles
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An omniphobic lubricant-infused coating produced by chemical vapor deposition of hydrophobic organosilanes attenuates clotting on catheter surfaces Journal Articles
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Andexanet Alfa for Factor Xa Inhibitor Reversal Journal Articles
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Andexanet Alfa for Reversal of Factor Xa Inhibitors: A Critical Review of the Evidence Journal Articles
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Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity Journal Articles
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Andexanet alfa for the treatment of hemorrhage Journal Articles
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Anticoagulant Effects of Heparin in Neonatal Plasma' Journal Articles
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Anticoagulant failure in coagulopathic patients: PTT confounding and other pitfalls Journal Articles
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Anticoagulant mechanisms of covalent antithrombin-heparin investigated by thrombelastography Journal Articles
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Anticoagulant therapy for splanchnic vein thrombosis Journal Articles
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Anticoagulants and Their Reversal Journal Articles
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Anticoagulants in atrial fibrillation patients with chronic kidney disease Journal Articles
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Anticoagulation Control with Daily Low‐Dose Vitamin K to Reduce Clinically Adverse Outcomes and International Normalized Ratio Variability: A Systematic Review and Meta‐Analysis Journal Articles
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Anticoagulation and in vitro fertilization and ovarian stimulation Journal Articles
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Anticoagulation for Atrial Fibrillation: State of the Art and Recommendations for a Quickly Moving Target Journal Articles
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Anticoagulation in patients with cerebral amyloid angiopathy Journal Articles
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Anticoagulation therapy in neonates, children and adolescents Journal Articles
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Anticoagulation therapy patterns for acute treatment of venous thromboembolism in GARFIELD‐VTE patients Journal Articles
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Anticoagulation with osocimab in patients with kidney failure undergoing hemodialysis: a randomized phase 2 trial Journal Articles
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Antidotes for Novel Oral Anticoagulants Journal Articles
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Antiphospholipid Syndrome During Septic Shock: Hyper- or Hypocoagulability?: A Case Report Journal Articles
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Antiphospholipid antibodies and recurrent thrombosis after a first unprovoked venous thromboembolism Journal Articles
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Antiplatelet Therapy versus Anticoagulation after Surgical Bioprosthetic Aortic Valve Replacement: A Systematic Review and Meta-Analysis Journal Articles
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Antithrombin alfa in hereditary antithrombin deficient patients: A phase 3 study of prophylactic intravenous administration in high risk situations Journal Articles
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Antithrombin-Independent Anticoagulation by Hypersulfated Low-Molecular-Weight Heparin Journal Articles
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Antithrombin-heparin covalent complex reduces microemboli during cardiopulmonary bypass in a pig model Journal Articles
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Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention Journal Articles
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Antithrombotic therapy in deep vein thrombosis and pulmonary embolism Journal Articles
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Antithrombotic therapy in deep vein thrombosis and pulmonary embolism. Journal Articles
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Are Ticks the Answer to Medical Device-Associated Clotting? Journal Articles
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Argatroban Anticoagulant Therapy in Patients With Heparin-Induced Thrombocytopenia Journal Articles
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Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein Journal Articles
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Aspirin Journal Articles
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Assays for Measuring Rivaroxaban: Their Suitability and Limitations Journal Articles
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Assessment of Anticoagulation Intensity and Management of Bleeding With Old and New Oral Anticoagulants Journal Articles
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Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis Journal Articles
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Autoimmune heparin‐induced thrombocytopenia Journal Articles
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Autologous transfusion of mediastinal drainage blood Journal Articles
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Basic coagulation tests as surrogates of dabigatran levels in a pre-operative setting: Analysis of five activated partial thromboplastin time reagents and thrombin time Journal Articles
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Betrixaban (PRT054021): pharmacology, Dose Selection and Clinical Studies Journal Articles
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Beyond heparin and warfarin: the new generation of anticoagulants Journal Articles
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Biologic rationale for the therapeutic role of specific antithrombins Journal Articles
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Bioregulatory roles for fibrin(ogen) on blood coagulation Journal Articles
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Bivalent Binding to γA/γ′-Fibrin Engages Both Exosites of Thrombin and Protects It from Inhibition by the Antithrombin-Heparin Complex Journal Articles
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Bivalirudin Journal Articles
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Bivalirudin, thrombin and platelets: clinical implications and future directions. Journal Articles
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Bleeding risk in randomized controlled trials comparing warfarin and aspirin: a systematic review and meta‐analysis Journal Articles
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Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in Atrial Fibrillation (BRAIN-AF): Methods and Design Journal Articles
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BloodSurf 2017: News from the blood-biomaterial frontier Journal Articles
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By Increasing the Affinity of Heparin for Fibrin, Zn2+ Promotes the Formation of a Ternary Heparin–Thrombin–Fibrin Complex That Protects Thrombin from Inhibition by Antithrombin Journal Articles
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C-reactive protein is a mediator of cardiovascular disease Journal Articles
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Cell-Free DNA Modulates Clot Structure and Impairs Fibrinolysis in Sepsis Journal Articles
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Challenges with heparin-based anticoagulation during cardiopulmonary bypass in children: Impact of low antithrombin activity Journal Articles
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Characterization of a Mouse Model for Thrombomodulin Deficiency Journal Articles
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Chemistry, Measurement, and Clinical Significance of Platelet Specific Proteins Journal Articles
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Chemotherapeutic agents doxorubicin and epirubicin induce a procoagulant phenotype on endothelial cells and blood monocytes Conferences
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Clopidogrel does not suppress blood markers of coagulation activation in aspirin-treated patients with non-ST-elevation acute coronary syndromes Journal Articles
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Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors. Journal Articles
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Coagulation Assays Journal Articles
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Coagulation Disorders and Blood Product Use in Patients Undergoing Thoracoabdominal Aortic Aneurysm Repair Journal Articles
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Coagulation and Fibrinolytic Profile of Paediatric Patients Undergoing Cardiopulmonary Bypass Journal Articles
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Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-Remitting Multiple Sclerosis Journal Articles
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Coagulopathy in a patient with nephrotic syndrome Journal Articles
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Comparison of the Proinflammatory and Procoagulant Properties of Nuclear, Mitochondrial, and Bacterial DNA Journal Articles
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Comparison of the anticoagulant intensities of fondaparinux and enoxaparin in the organization to assess strategies in acute ischemic syndromes (OASIS)‐5 trial Journal Articles
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Comparison of the effect of coagulation and platelet function
impairments on various mouse bleeding models Journal Articles
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Comparison of the effects of apixaban and rivaroxaban on prothrombin and activated partial thromboplastin times using various reagents Journal Articles
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Congenital Thrombophilic States Associated with Venous Thrombosis: A Qualitative Overview and Proposed Classification System Journal Articles
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Contribution of Red Blood Cells to the Saturable Mechanism of Heparin Clearance Journal Articles
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Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo Journal Articles
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Cost-effectiveness of Dabigatran and Rivaroxaban Compared with Warfarin for Stroke Prevention in Patients with Atrial Fibrillation Journal Articles
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Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va Journal Articles
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Covalent antithrombin–heparin complexes Journal Articles
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Covalently linking heparin to antithrombin enhances prothrombinase inhibition on activated platelets Journal Articles
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Critical Values in the Coagulation Laboratory Results of a Survey of the North American Specialized Coagulation Laboratory Association Journal Articles
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Current use of biologicals in thrombosis and haemostasis Journal Articles
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DAMP and DIC: The role of extracellular DNA and DNA-binding proteins in the pathogenesis of DIC Journal Articles
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Dabigatran Etexilate: Future Directions in Anticoagulant Treatment Journal Articles
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Dabigatran Reversal With Idarucizumab in Patients Requiring Urgent Surgery Journal Articles
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Dabigatran Reversal With Idarucizumab in Patients With Renal Impairment Journal Articles
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Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function Journal Articles
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Dabigatran efficacy‐safety assessment for stroke prevention in patients with atrial fibrillation Journal Articles
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Dabigatran etexilate and reduction in serum apolipoprotein B Journal Articles
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Dabigatran monitoring made simple? Journal Articles
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Ddavp-induced correction of prolonged bleeding time in patients with congenital platelet function defects Journal Articles
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Decreased Thrombin Activity of Fibrin Clots Prepared in Cord Plasma Compared with Adult Plasma Journal Articles
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Decreased platelet thrombogenecity in association with increased platelet turnover and vascular damage Journal Articles
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Definition of haemostatic effectiveness in interventions used to treat major bleeding: Communication from the ISTH SSC Subcommittee on Control of Anticoagulation Journal Articles
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Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran Journal Articles
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Development of the human coagulation system in the full-term infant Journal Articles
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Development of the human coagulation system in the healthy premature infant Journal Articles
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Diagnosis and management of sepsis‐induced coagulopathy and disseminated intravascular coagulation Journal Articles
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Diannexin, an annexin A5 homodimer, binds phosphatidylserine with high affinity and is a potent inhibitor of platelet‐mediated events during thrombus formation Journal Articles
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Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation Journal Articles
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Differential Expression of PCSK9 Modulates Infection, Inflammation, and Coagulation in a Murine Model of Sepsis Journal Articles
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Direct Oral Anticoagulants Journal Articles
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Direct oral anticoagulant dose selection: Challenging cases Journal Articles
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Direct thrombin inhibitors in cardiovascular disease Journal Articles
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Dual surface modification of polydimethylsiloxane (PDMS) with antithrombin-heparin complex (ATH) and tissue plasminogen activator (t-PA) for enhanced antithrombotic activity. Journal Articles
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EPIDEMIOLOGY AND PATHOGENESIS OF VENOUS THROMBOSIS Journal Articles
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EVALUATION OF SUBCUTANEOUS CALCIUM HEPARIN THERAPY IN THE TREATMENT OF THROMBO‐EMBOLIC DISEASE Journal Articles
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EXPERIMENTAL PRODUCTION OF MICROANGIOPATHIC HÆMOLYTIC ANÆMIA IN VIVO Journal Articles
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Edoxaban for the Prevention of Thromboembolism in Patients With Atrial Fibrillation and Bioprosthetic Valves Journal Articles
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Effect of Dermatan Sulphate on Activated Partial Thromboplastin Time Determined with Different Reagents Journal Articles
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Effect of Drugs on Platelets and Complications of Vascular Disease Other
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Effect of RA233 on Platelet Function In Vitro Journal Articles
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Effect of Reversal of Neuromuscular Blockade with Sugammadex versus Usual Care on Bleeding Risk in a Randomized Study of Surgical Patients Journal Articles
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Effect of Streptokinase on Hemostasis Journal Articles
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Effect of Warfarin on Activated Partial Thromboplastin Time in Patients Receiving Heparin Journal Articles
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Effect of a simple two‐step warfarin dosing algorithm on anticoagulant control as measured by time in therapeutic range: a pilot study Journal Articles
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Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex. Journal Articles
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Effect of gaboon viper (Bitis gabonica) venom on blood coagulation, platelets, and the fibrinolytic enzyme system Journal Articles
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Effect of standardized perioperative dabigatran interruption on the residual anticoagulation effect at the time of surgery or procedure Journal Articles
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Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography Journal Articles
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Effectin vitroon platelet function of two compounds developed from the pyrimido-pyrimidines Journal Articles
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Effects of Continuous Plasma-Derived Subcutaneous C1-Esterase Inhibitor on Coagulation and Fibrinolytic Parameters Journal Articles
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Effects of genetic fusion of factor IX to albumin on in vivo clearance in mice and rabbits Conferences
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Effects of heparin fractions of different affinities to antithrombin III and thrombin on the inactivation of thrombin and factor Xa by antithrombin III Journal Articles
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Effects of the chemotherapeutic agent doxorubicin on the protein C anticoagulant pathway Journal Articles
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Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran-induced anticoagulation Journal Articles
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Emerging anticoagulant strategies Journal Articles
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Epidemiology and pathogenesis of venous thrombosis Journal Articles
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EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis Journal Articles
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Estimating and interpreting the pharmacokinetic profiles of individual patients with hemophilia A or B using a population pharmacokinetic approach: communication from the SSC of the ISTH Journal Articles
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Evaluating coagulation tests in patients with atrial fibrillation using direct oral anticoagulants Journal Articles
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Evolution of Thrombosis Journal Articles
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Examining therapeutic equivalence between branded and generic warfarin in Brazil: The WARFA crossover randomized controlled trial Journal Articles
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Exosites 1 and 2 Are Essential for Protection of Fibrin-bound Thrombin from Heparin-catalyzed Inhibition by Antithrombin and Heparin Cofactor II Journal Articles
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Extended treatment with edoxaban in cancer patients with venous thromboembolism: A post‐hoc analysis of the Hokusai‐VTE Cancer study Journal Articles
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Extending the pre-processing holding time of whole blood beyond 48 h reduces coagulation FVIII activity and immunoglobulin G content of recovered plasma Journal Articles
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Extracellular DNA and histones: double‐edged swords in immunothrombosis Journal Articles
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Extracellular Histones Increase Tissue Factor Activity and Enhance Thrombin Generation by Human Blood Monocytes Journal Articles
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Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis Journal Articles
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Factor XI Inhibition to Uncouple Thrombosis From Hemostasis Journal Articles
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Factor XI and factor XII as targets for new anticoagulants Journal Articles
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Factor XI inhibitors: cardiovascular perspectives Journal Articles
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Factors and inhibitors of blood coagulation and fibrinolysis in acute nonlymphoblastic leukaemia Journal Articles
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Failure of Aspirin to Prevent Atherothrombosis Journal Articles
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Failure to correct International Normalized Ratio and mortality among patients with warfarin‐related major bleeding: an analysis of electronic health records Journal Articles
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Feasibility of blood conservation strategies in pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension Journal Articles
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Fibrinolytic System in Adolescents: Response to Venous Occlusion Stress Tests Journal Articles
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Fibrinolytic response to venous occlusion is decreased in patients after Kawasaki disease Journal Articles
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Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT) – Bridging the River Coumarin Journal Articles
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Gastrointestinal Bleeding With Edoxaban Versus Warfarin Journal Articles
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General mechanisms of coagulation and targets of anticoagulants (Section I) Journal Articles
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Genetics of Coagulation: What the Cardiologist Needs to Know Journal Articles
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Genotype-guided versus standard vitamin K antagonist dosing algorithms in patients initiating anticoagulation Journal Articles
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Guide to Anticoagulant Therapy: Heparin Journal Articles
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HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions Journal Articles
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HEPARIN-BINDING PROTEINS - CONTRIBUTION TO HEPARIN REBOUND AFTER CARDIOPULMONARY BYPASS Journal Articles
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Healthcare resource use in XALIA: A subgroup analysis of a non-interventional study of rivaroxaban versus standard anticoagulation for deep vein thrombosis Journal Articles
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Healthcare resource utilization in patients receiving idarucizumab for reversal of dabigatran anticoagulation due to major bleeding, urgent surgery, or procedural interventions: interim results from the RE-VERSE AD™ study Journal Articles
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Hemodialysis for the treatment of dabigatran‐associated bleeding: a case report and systematic review Journal Articles
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Hemostatic alterations in cancer patients Journal Articles
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Hemostatic efficacy of pathogen-inactivated vs untreated platelets: a randomized controlled trial Journal Articles
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Heparin binding proteins. Contribution to heparin rebound after cardiopulmonary bypass. Journal Articles
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Heparin induced thrombocytopenia Journal Articles
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Heparin sensitivity and resistance in the neonate: An explanation Journal Articles
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Heparin with low affinity to antithrombin III inhibits the activation of prothrombin in normal plasma Journal Articles
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Heparin, DDAVP and the Bleeding Time Journal Articles
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Heparin-induced Thrombocytopenia Journal Articles
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Heparin: Mechanism of Action, Pharmacokinetics, Dosing Considerations, Monitoring, Efficacy, and Safety Journal Articles
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Heparin: mechanism of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety. Journal Articles
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Hirudin causes more bleeding than heparin in a rabbit ear bleeding model Journal Articles
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Histidine-Rich Glycoprotein Modulates the Toxic Effects of High-Dose Polyphosphate in Mice Journal Articles
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Histidine-rich glycoprotein attenuates catheter thrombosis Journal Articles
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Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic coagulation pathway Journal Articles
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Histidine-rich glycoprotein binds factor XIIa with high affinity and inhibits contact-initiated coagulation Journal Articles
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Homocyst(e)ine and Cardiovascular Disease Journal Articles
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Homocysteine-Lowering Treatment With Folic Acid, Cobalamin, and Pyridoxine Does Not Reduce Blood Markers of Inflammation, Endothelial Dysfunction, or Hypercoagulability in Patients With Previous Transient Ischemic Attack or Stroke Journal Articles
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How I treat recurrent venous thromboembolism in patients receiving anticoagulant therapy Journal Articles
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How do we approach thrombocytopenia in critically ill patients? Journal Articles
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Hypercoagulability after trauma: Hemostatic changes and relationship to venous thromboembolism Journal Articles
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Hypercoagulability. Journal Articles
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Hypersulfated Low Molecular Weight Heparin with Reduced Affinity for Antithrombin Acts as an Anticoagulant by Inhibiting Intrinsic Tenase and Prothrombinase Journal Articles
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INVIVO EFFECTS OF LOW-MOLECULAR-WEIGHT HEPARINS ON EXPERIMENTAL THROMBOSIS AND BLEEDING Journal Articles
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ISTH DIC subcommittee communication on anticoagulation in COVID‐19 Journal Articles
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Idarucizumab for Dabigatran Reversal Journal Articles
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Idarucizumab for Dabigatran Reversal — Full Cohort Analysis Journal Articles
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Idarucizumab for dabigatran overdose Journal Articles
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Idiopathic gangrene in African children. Journal Articles
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Immobilization of an antithrombin–heparin complex on gold: Anticoagulant properties and platelet interactions Journal Articles
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Impact of Arterial Procedures on Coagulation and Fibrinolysis – A Pilot Study Journal Articles
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Impact of Spontaneous Extracranial Bleeding Events on Health State Utility in Patients with Atrial Fibrillation: Results from the ENGAGE AF‐TIMI 48 Trial Journal Articles
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Impact of Switching From a Vitamin K Antagonist to Rivaroxaban on Satisfaction With Anticoagulation Therapy: The XANTUS‐ACTS Substudy Journal Articles
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Impact of sample processing delays on plasma markers of inflammation, chemotaxis, cell death, and blood coagulation. Journal Articles
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Impaired Fibrinolytic Activity Is Present in Children with Dyslipidemias Journal Articles
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Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries Journal Articles
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In vitro comparison of the effect of heparin, enoxaparin and fondaparinux on tests of coagulation Journal Articles
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In vivo Effects of Low Molecular Weight Heparins on Experimental Thrombosis and Bleeding Journal Articles
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In vivo rabbit acute model tests of polyurethane catheters coated with a novel antithrombin-heparin covalent complex Journal Articles
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Incident Atrial Fibrillation, Dementia and the Role of Anticoagulation: A Population-Based Cohort Study Journal Articles
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Incorporation of Fragment X into Fibrin Clots Renders Them More Susceptible to Lysis by Plasmin Journal Articles
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Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa Journal Articles
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Infection-Induced Thrombocytopenia Journal Articles
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Inherited Thrombophilia and the Risk of Arterial Ischemic Stroke: A Systematic Review and Meta‐Analysis Journal Articles
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Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of α-thrombin Journal Articles
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Inhibition of the prothrombinase complex on red blood cells by heparin and covalent antithrombin-heparin complex Journal Articles
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Intensified antiplatelet therapy in patients after percutaneous coronary intervention with high on‐treatment platelet reactivity: the OPTImal Management of Antithrombotic Agents (OPTIMA)‐2 Trial Journal Articles
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Interactions of fibrinolytic system proteins with lysine‐containing surfaces Journal Articles
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International Normalized Ratio Targets for Left-Sided Mechanical Valve Replacement Journal Articles
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Investigation of the Anticoagulant Mechanisms of a Covalent Antithrombin-Heparin Complex Journal Articles
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Kinetic Analysis of a Unique Direct Prothrombinase, fgl2, and Identification of a Serine Residue Critical for the Prothrombinase Activity Journal Articles
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Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants Journal Articles
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Laboratory Monitoring of Oral Vitamin K Anticoagulation Journal Articles
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Laboratory assessment of the anticoagulant effects of the next generation of oral anticoagulants Journal Articles
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Laboratory measurement of the direct oral anticoagulants Journal Articles
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Latest medical treatment strategies for venous thromboembolism Journal Articles
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Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development Journal Articles
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Long-Term Risk of Major Bleeding after Discontinuing Anticoagulation for Unprovoked Venous Thromboembolism: A Systematic Review and Meta-analysis Journal Articles
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Low molecular weight heparin Journal Articles
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Low-dose oral vitamin K is safe and effective for outpatient management of patients with an INR>10 Journal Articles
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Low-dose oral vitamin K therapy for the management of asymptomatic patients with elevated international normalized ratios: a brief review Journal Articles
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Low-dose oral vitamin K to normalize the international normalized ratio prior to surgery in patients who require temporary interruption of warfarin Journal Articles
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Lupus Anticoagulant Testing Journal Articles
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Lysine-PEG-modified polyurethane as a fibrinolytic surface: Effect of PEG chain length on protein interactions, platelet interactions and clot lysis Journal Articles
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MAA868 locks factor XIa in a zymogen-like state Journal Articles
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Magnesium interrelationships in ischemic heart disease: a review Journal Articles
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Magnetic resonance venography to assess thrombus resolution with edoxaban monotherapy versus parenteral anticoagulation/warfarin for symptomatic deep vein thrombosis: A multicenter feasibility study Journal Articles
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Management of Excessive Anticoagulant Effect Due to Vitamin K Antagonists Journal Articles
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Massive transfusion Journal Articles
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Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13 Journal Articles
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Measurement of Markers of Activated Coagulation in Antithrombin III Deficient Subjects Journal Articles
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Mechanism of catheter thrombosis: comparison of the antithrombotic activities of fondaparinux, enoxaparin, and heparin in vitro and in vivo Journal Articles
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Medical device‐induced thrombosis: what causes it and how can we prevent it? Journal Articles
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Mice with deleted multimerin 1 and α-synuclein genes have impaired platelet adhesion and impaired thrombus formation that is corrected by multimerin 1 Journal Articles
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Microangiopathic Haemolytic Anaemia (MHA) Journal Articles
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Microangiopathic Haemolytic Anaemia: Mechanisms of Red‐Cell Fragmentation: in Vitro Studies Journal Articles
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Microangiopathic haemolytic anaemia: experimental production of fragmented erythrocytes in vitro. Journal Articles
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Microvesicles: ubiquitous contributors to infection and immunity Journal Articles
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Mimicking the fibrinolytic system on material surfaces Journal Articles
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Modification of Polyurethane with Polyethylene Glycol–Corn Trypsin Inhibitor for Inhibition of Factor Xlla in Blood Contact Journal Articles
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Modification of platelet function Other
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Modulation of Monocyte Function by Activated Protein C, a Natural Anticoagulant Journal Articles
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Monitoring patients with the lupus anticoagulant while treated with vitamin K antagonists: communication from the SSC of the ISTH Journal Articles
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Monitoring the anticoagulant effect after a massive rivaroxaban overdose Journal Articles
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More Effective Suppression of Hemostatic System Activation in Patients Undergoing Cardiac Surgery by Heparin Dosing Based on Heparin Blood Concentrations rather than ACT Journal Articles
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Morphological and Biochemical Features Affecting the Antithrombotic Properties of the Aorta in Adult Rabbits and Rabbit Pups Journal Articles
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Mortality in vitamin K antagonist-related intracerebral bleeding treated with plasma or 4-factor prothrombin complex concentrate Journal Articles
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NXY‐059 Does Not Affect Bleeding Time in Healthy Volunteers: A Randomized, Double‐Blind, Placebo‐Controlled, 3‐Period Crossover Phase I Study Journal Articles
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Neonatal and childhood right atrial thrombosis Journal Articles
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Neutrophil Extracellular Traps Promote Thrombin Generation Through Platelet-Dependent and Platelet-Independent Mechanisms Journal Articles
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New Anti-thrombotic Agents: Emphasis on Hemorrhagic Complications and Their Management Conferences
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New Anticoagulant Drugs Journal Articles
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New Anticoagulants Journal Articles
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New Concepts in Coagulation Journal Articles
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New Therapeutic Targets for the Prevention and Treatment of Venous Thromboembolism With a Focus on Factor XI Inhibitors Journal Articles
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New anticoagulants Conferences
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New anticoagulants Conferences
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New anticoagulants. Journal Articles
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New anticoagulants: Moving beyond the direct oral anticoagulants Journal Articles
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New anticoagulants: an update. Journal Articles
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New artificial intelligence prediction model using serial prothrombin time international normalized ratio measurements in atrial fibrillation patients on vitamin K antagonists: GARFIELD-AF Journal Articles
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New oral anticoagulants in atrial fibrillation Journal Articles
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New oral anticoagulants in development Journal Articles
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No Association Between Protein C Levels and Bacteremia in Children With Febrile Neutropenia Journal Articles
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Nonvitamin K antagonist oral anticoagulant use in patients with renal impairment Journal Articles
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Novel anticoagulant agents: introduction Journal Articles
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Optimizing the safety of treatment for venous thromboembolism in the era of the direct oral anticoagulants Journal Articles
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Oral Anticoagulant Initiation: Rationale for the Use of Warfarin Dosing Nomograms Journal Articles
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Oral Anticoagulation Treatment in the Elderly Journal Articles
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Oral, Direct Factor Xa Inhibitors in Development for the Prevention and Treatment of Thromboembolic Diseases Journal Articles
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Orally Active Direct Thrombin Inhibitors Journal Articles
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Outcomes and predictors of very stable INR control during chronic anticoagulation therapy Journal Articles
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Outcomes of Patients with a Mechanical Heart Valve and Poor Anticoagulation Control on Warfarin Journal Articles
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Overexpression of the 78-kDa Glucose-regulated Protein/Immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity Journal Articles
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PROTEOLYTIC DEGRADATION OF HIGH MOLECULAR WEIGHT KININOGEN IN ACUTE THROMBOTIC THROMBOCYTOPENIC PURPURA Journal Articles
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Parenteral anticoagulants in heart disease: Current status and perspectives (Section II) Journal Articles
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Pathogen reduction of whole blood: Supplementing fibrinogen partly corrects clot formation in a massive transfusion model Journal Articles
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Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial Journal Articles
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Perioperative Management of Anticoagulation Journal Articles
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Perioperative cardiovascular complications rate and activity of coagulation and fibrinolysis among patients undergoing vascular surgery for peripheral artery disease and abdominal aortic aneurysm Journal Articles
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Periprocedural Management of Oral Anticoagulation in Patients With Atrial Fibrillation: Approach in the Era of New Oral Anticoagulants Journal Articles
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Periprocedural interruption of anticoagulation in patients with cancer‐associated venous thromboembolism: An analysis of thrombotic and bleeding outcomes Journal Articles
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Periprocedural management of direct oral anticoagulants in patients with atrial fibrillation and active cancer Journal Articles
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Pharmacokinetics of High‐Dose Abetimus Sodium in Normal Subjects With Specific Assessment of Effect on Coagulation Journal Articles
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Pharmacological Actions of Sulodexide Journal Articles
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Phosphatidylinositol 4,5-bisphosphate is selectively retained by platelet-fibrin clots formed by thrombin Journal Articles
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Phosphatidylserine externalization and procoagulant activation of erythrocytes induced by Pseudomonas aeruginosa virulence factor pyocyanin Journal Articles
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Plasma Anticoagulant Mechanisms of Heparin, Heparan Sulfate, and Dermatan Sulfatea Journal Articles
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Plasma fibronectin supports hemostasis and regulates thrombosis Journal Articles
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Platelet PECAM-1 inhibits thrombus formation in vivo Journal Articles
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Platelet polyphosphate: the long and the short of it Journal Articles
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Pleiotropic actions of factor Xa inhibition in cardiovascular prevention: mechanistic insights and implications for anti-thrombotic treatment Journal Articles
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Polyphosphate-induced thrombosis in mice is factor XII dependent and is attenuated by histidine-rich glycoprotein Journal Articles
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Polyurethanes bearing pendant amino acids: Fibrinogen adsorption and coagulant properties Journal Articles
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Postoperative atrial fibrillation in non‐cardiac and cardiac surgery: an overview Journal Articles
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Practical guidance for using rivaroxaban in patients with atrial fibrillation: balancing benefit and risk Journal Articles
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Probable regulation of factor VIIa–tissue factor and prothrombinase by factor Xa–TFPI and TFPI in vivo Journal Articles
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Profile of patients diagnosed with acute venous thromboembolism in routine practice according to age and renal function: RE-COVERY DVT/PE study Journal Articles
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Prolonged Expression of Procoagulant Activity of Human Platelets Degranulated by Thrombin Journal Articles
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Prolonged hemorrhagic shock does not impair regeneration of plasma coagulant masses in the rabbit Journal Articles
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Prophylactically Effective Doses of Enoxaparin and Heparin Inhibit Prothrombin Activation Journal Articles
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Proposal of a two‐step process for the diagnosis of sepsis‐induced disseminated intravascular coagulation Journal Articles
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Protein C Assay Performance Journal Articles
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Protein adsorption on polyurethane catheters modified with a novel antithrombin‐heparin covalent complex Journal Articles
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Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Journal Articles
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Purification of silica‐free DNA and characterization of its role in coagulation Journal Articles
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Quantitation of human megakaryocyte progenitors (CFU-M) in plasma clot culture by an indirect immunoperoxidase method. Journal Articles
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RE-COVERY DVT/PE: Rationale and design of a prospective observational study of acute venous thromboembolism with a focus on dabigatran etexilate Journal Articles
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Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation Journal Articles
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Randomized phase 2 trial comparing JNJ‐9375, a thrombin‐directed antibody, with apixaban for prevention of venous thrombosis Journal Articles
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Rapid diagnosis of coagulopathies from vitamin K deficiency in a consecutive case cohort evaluated by comparative assessment of factor II by one stage assays with prothrombin time versus Ecarin reagents Journal Articles
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Rationale Behind the Development of Low Molecular Weight Heparin Derivatives Journal Articles
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Reactivation of coagulation after stopping infusions of recombinant hirudin and unfractionated heparin in unstable angina and myocardial infarction without ST elevation: results of a randomized trial Journal Articles
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Real-life treatment of venous thromboembolism with direct oral anticoagulants: The influence of recommended dosing and regimens Journal Articles
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Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse Journal Articles
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Real-world variability in dabigatran levels in patients with atrial fibrillation: reply Journal Articles
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Real‐world variability in dabigatran levels in patients with atrial fibrillation Journal Articles
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Reasons for resistance to aspirin in cardiovascular disease. Journal Articles
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Recent Advances in Thrombosis and Hemostasis – Part I Journal Articles
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Recommendation on the nomenclature for anticoagulants: updated communication from the International Society on Thrombosis and Haemostasis Scientific and Standardization Commitee on the Control of Anticoagulation Journal Articles
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Recommendations for the development of new anticoagulant drugs for pediatric use: communication from the SSC of the ISTH Journal Articles
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Reduced Dose Bolus Alteplase vs Conventional Alteplase Infusion for Pulmonary Embolism Thrombolysis Journal Articles
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Reduced Plasminogen Binding and Delayed Activation Render γ′-Fibrin More Resistant to Lysis than γA-Fibrin Journal Articles
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Reduced‐dose direct oral anticoagulants in the extended treatment of venous thromboembolism: a systematic review and meta‐analysis Journal Articles
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Relation Between Bleeding Time and Platelet Connective Tissue Reaction After Aspirin Journal Articles
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Relationship Between Dose, Anticoagulant Effect and the Clinical Efficacy and Safety of Heparin Conferences
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Relationship between the anticoagulant and antithrombotic effects of heparin in experimental venous thrombosis Journal Articles
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Report of the Subcommittee of Control of Anticoagulation on the determination of the anticoagulant effects of rivaroxaban Journal Articles
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Residual vein obstruction as a predictor for recurrent thromboembolic events after a first unprovoked episode: data from the REVERSE cohort study Journal Articles
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Respective role of antithrombin III and heparin cofactor II in the in vitro anticoagulant effect of heparin and of various sulphated polysaccharides Journal Articles
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Reversal agents for non-vitamin K antagonist oral anticoagulants Journal Articles
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Reversal of dabigatran-associated major bleeding with activated prothrombin concentrate: A prospective cohort study Journal Articles
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Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH Journal Articles
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Reversible endotension associated with excessive warfarin anticoagulation Journal Articles
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Risk of post‐thrombotic syndrome after subtherapeutic warfarin anticoagulation for a first unprovoked deep vein thrombosis: results from the REVERSE study Journal Articles
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Rivaroxaban and dabigatran did not affect clotting profiles in plasma reconstituted with varying levels of autologous platelets to the same degree as heparin when evaluated using thromboelastography Journal Articles
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Rivaroxaban for Preventing Venous Thromboembolism in High-Risk Ambulatory Patients with Cancer: Rationale and Design of the CASSINI Trial Journal Articles
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Rivaroxaban for Prevention and Treatment of Venous Thromboembolism Journal Articles
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Rivaroxaban for treatment of pediatric venous thromboembolism. An Einstein‐Jr phase 3 dose‐exposure‐response evaluation Journal Articles
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Rivaroxaban reversal with prothrombin complex concentrate or tranexamic acid in healthy volunteers Journal Articles
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Rivaroxaban with or without aspirin for prevention of cardiovascular disease Journal Articles
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Role of new anticoagulants for the prevention of venous thromboembolism after major orthopaedic surgery and in hospitalised acutely ill medical patients Journal Articles
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Selection and assessment of patients treated with the novel oral anticoagulant drugs: a recommendation from the Subcommittee on Control of Anticoagulation of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis Journal Articles
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Setting a standard for venous thromboembolism prophylaxis Journal Articles
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Shock, acute disseminated intravascular coagulation, and microvascular thrombosis: is ‘shock liver’ the unrecognized provocateur of ischemic limb necrosis? Journal Articles
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Shortening of the Bleeding Time in Rabbits by Hydrocortisone Caused by Inhibition of Prostacyclin Generation by the Vessel Wall Journal Articles
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Should vitamin K antagonist therapy be started simultaneously with parenteral anticoagulation Journal Articles
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Small Molecules Targeting GRP78 Mitigate Anti- GRP78 Autoantibody-Mediated Tissue Factor Procoagulant Activity in Cultured Endothelial Cells Journal Articles
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Special series on challenging anticoagulation cases: Experience counts when guidelines fall short Journal Articles
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Spotlight on animal models of acute traumatic coagulopathy: an update Journal Articles
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Stirred, shaken, or stagnant: What goes on at the blood–biomaterial interface Journal Articles
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Storage of thawed plasma for a liquid plasma bank: impact of temperature and methylene blue pathogen inactivation Journal Articles
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Stroke Prevention in Atrial Fibrillation Patients With Chronic Kidney Disease Journal Articles
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Studies on East African Snakes Journal Articles
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Subtle differences in commercial heparins can have serious consequences for cardiopulmonary bypass patients: A randomized controlled trial Journal Articles
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Supplemental patient education for patients taking oral anticoagulants: systematic review and meta-analysis Journal Articles
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Surface modification of polydimethylsiloxane with a covalent antithrombin–heparin complex to prevent thrombosis Journal Articles
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Surface modification with an antithrombin–heparin complex for anticoagulation: Studies on a model surface with gold as substrate Journal Articles
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Targeting Tumor Vasculature With an Oncolytic Virus Journal Articles
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The APTT Response of Pregnant Plasma to Unfractionated Heparin Journal Articles
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The Basic Principles of Pathophysiology of Venous Thrombosis. Journal Articles
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The Coagulation System in Humans Journal Articles
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The Effects of Low-intensity Warfarin on Coagulation Activation in Patients with Antiphospholipid Antibodies and Systemic Lupus Erythematosus Journal Articles
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The Effects of Steroids on Coagulation Dysfunction Induced by Cardiopulmonary Bypass: A Steroids in Cardiac Surgery (SIRS) Trial Substudy Journal Articles
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The Influence of Perioperative Coagulation Status on Postoperative Blood Loss in Complex Cardiac Surgery Journal Articles
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The M358R variant of α 1 -proteinase inhibitor inhibits coagulation factor VIIa Journal Articles
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The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations Journal Articles
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The Structural Integrity of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII Journal Articles
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The accuracy of the International Normalized Ratio and the American College of Chest Physicians recommendations on the use of vitamin K to reverse over-anticoagulation: a rebuttal Journal Articles
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The activation of coagulation by extracts of mucus: a possible pathway of intravascular coagulation accompanying adenocarcinomas. Journal Articles
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The appended tail region of heparin cofactor II and additional reactive centre loop mutations combine to increase the reactivity and specificity of α1-proteinase inhibitor M358R for thrombin Journal Articles
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The association of anticoagulation, ischemic stroke, and hemorrhage in elderly adults with chronic kidney disease and atrial fibrillation Journal Articles
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The blood compatibility challenge. Part 1: Blood-contacting medical devices: The scope of the problem Journal Articles
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The blood compatibility challenge. Part 2: Protein adsorption phenomena governing blood reactivity Journal Articles
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The blood platelet as a model for regulating blood coagulation on cell surfaces and its consequences. Journal Articles
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The conundrum of resuming anticoagulant therapy after intracerebral bleeding: In whom, when, and how? Journal Articles
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The direct binding of human factor VII in plasma to recombinant human tissue factor Journal Articles
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The direct thrombin inhibitor hirudin Journal Articles
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The effect of aspirin inhibition of PGI2 production on platelet adherence to normal and damaged rabbit aortae Journal Articles
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The effect of chemical structure and surface properties of synthetic polymers on the coagulation of blood. II. Protein and platelet interaction with polymer surfaces. Journal Articles
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The effect of low-dose oral vitamin K supplementation on INR stability in patients receiving warfarin Journal Articles
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The effects of high-dose heparin on inflammatory and coagulation parameters following cardiopulmonary bypass Journal Articles
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The effects of timing of prophylaxis, type of anesthesia, and use of mechanical methods on outcome in major orthopedic surgery - subgroup analyses from 17,701 patients in the XAMOS study Journal Articles
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The evolving treatment of peripheral arterial disease: preventing ischaemic events in the post-COMPASS era Journal Articles
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The haemorrhagic and antithrombotic effects of dermatan sulphate Journal Articles
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The haemorrhagic and antithrombotic effects of dermatan sulphate. Journal Articles
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The historical origins of modern international normalized ratio targets Journal Articles
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The impact of the endothelial protein C receptor on thrombin generation and clot lysis Journal Articles
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The influence of drugs upon the anticoagulant activity of heparin. Journal Articles
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The inhibition by heparin of the intrinsic pathway activation of factor X in the absence of antithrombin-III Journal Articles
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The inhibition of the anticoagulant activity of heparin by platelets, brain phospholipids, and tissue factor Journal Articles
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The interaction of platelets with polymer surfaces. I. Uncharged hydrophobic polymer surfaces. Journal Articles
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The mechanism of action of thrombin inhibitors. Journal Articles
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The multiple faces of the partial thromboplastin time APTT Journal Articles
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The need for accurate D‐dimer reporting in COVID‐19: Communication from the ISTH SSC on fibrinolysis Journal Articles
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The onerous task of comparing treatments in inhibitor patients Journal Articles
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The paradox of heparin‐induced thrombocytopenia Journal Articles
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The relationship between the hemorrhagic and antithrombotic properties of low molecular weight heparin in rabbits Journal Articles
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The relative kinetics of clotting and lysis provide a biochemical rationale for the correlation between elevated fibrinogen and cardiovascular disease Journal Articles
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The role of microRNAs in prethrombotic status associated with coronary artery disease Journal Articles
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The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression Journal Articles
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The serological profile of early-onset and persisting post-cardiac surgery thrombocytopenia complicated by “true” heparin-induced thrombocytopenia Journal Articles
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The status of new anticoagulants Journal Articles
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The temporal changes of hemostatic activity in hospitalized patients with COVID-19: a prospective observational study Journal Articles
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The thrombogenicity of C1 esterase inhibitor (human): Review of the evidence Journal Articles
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Thrombin Generation Journal Articles
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Thrombin and Antithrombotics Journal Articles
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Thrombin generation abnormalities in commonly encountered platelet function disorders Journal Articles
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Thrombin generation and bleeding in cardiac surgery: a clinical narrative review Journal Articles
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Thrombin generation, bleeding and hemostasis in humans: Protocol for a scoping review of the literature Journal Articles
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Thrombin structure and function Journal Articles
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Thrombogenic Effect of High-Dose Aspirin in Rabbits Journal Articles
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Thrombosis in children with malignancy Journal Articles
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Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndrome Journal Articles
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Thrombus stability explains the factor V Leiden paradox: a mouse model Journal Articles
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Tissue Factor and Thrombosis Models Journal Articles
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Tissue plasminogen activator-containing polyurethane surfaces for fibrinolytic activity Journal Articles
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Toll-like receptors 2 and 7 mediate coagulation activation and coagulopathy in murine sepsis. Journal Articles
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Treatment Challenges in Venous Thromboembolism: An Appraisal of Rivaroxaban Studies Journal Articles
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Treatment of warfarin-associated coagulopathy with oral vitamin K: a randomised controlled trial Journal Articles
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Twelve‐month outcomes and predictors of very stable INR control in prevalent warfarin users Journal Articles
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Type 1 Plasminogen Activator Inhibitor Binds to Fibrin via Vitronectin Journal Articles
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Understanding Thrombin and Hemostasis Journal Articles
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Unfavourable effects of medically indicated oral anticoagulants on survival in idiopathic pulmonary fibrosis Journal Articles
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Unfractionated heparin dosing in young infants: clinical outcomes in a cohort monitored with anti‐factor Xa levels Journal Articles
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Update on the Treatment of Venous Thromboembolism Journal Articles
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Urokinase Therapy: Dosage Schedules and Coagulant Side Effects Journal Articles
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Urokinase has direct catalytic activity against fibrinogen and renders it less clottable by thrombin. Journal Articles
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Venous and arterial thrombosis – pathogenesis and the rationale for anticoagulation Journal Articles
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Very severe thrombocytopenia and fragmentation hemolysis mimicking thrombotic thrombocytopenic purpura associated with a giant intracardiac vegetation infected with Staphylococcus epidermidis: Role of monocyte procoagulant activity induced by bacterial supernatant Journal Articles
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Vitamin K antagonists in heart disease: Current status and perspectives (Section III) Journal Articles
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Vitamin K to reverse the anticoagulant effect of vitamin K antagonists: can you teach an old dog new tricks? Journal Articles
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Volutrauma activates the clotting cascade in the newborn but not adult rat Journal Articles
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What can ex vivo experiments contribute to clinical haemostasis management? Journal Articles
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When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH Journal Articles
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Which Patients With Atrial Fibrillation and Chronic Kidney Disease Should Receive Anticoagulation—And With Which Anticoagulant? Journal Articles
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Why Did Your Mother Reject You? Immunogenetic Determinants of the Response to Environmental Selective Pressure Expressed at the Uterine Level Journal Articles
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Zinc promotes clot stability by accelerating clot formation and modifying fibrin structure Journal Articles
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Zinc: An important cofactor in haemostasis and thrombosis Journal Articles
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c.1058C>T variant in the SERPINC1 gene is pathogenic for antithrombin deficiency Journal Articles
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γT‐S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo Journal Articles