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The effect of low-dose oral vitamin K...
Journal article

The effect of low-dose oral vitamin K supplementation on INR stability in patients receiving warfarin

Abstract

The anticoagulant effect of warfarin is influenced by variations in vitamin K intake. Concomitant use of daily low-dose oral vitamin K (LDVK) and warfarin may improve INR stability. We hypothesise that administration of LDVK improves INR control. To test this hypothesis we performed a multi-centre, placebo-controlled, randomised trial conducted at four university-affiliated hospitals in Canada. Patients on chronic warfarin therapy received oral …

Authors

Boonyawat K; Wang L; Lazo-Langner A; Kovacs MJ; Yeo E; Schnurr T; Schulman S; Crowther MA

Journal

Thrombosis and Haemostasis, Vol. 116, No. 03, pp. 480–485

Publisher

Thieme

Publication Date

2016

DOI

10.1160/th16-04-0320

ISSN

0340-6245