Journal article
Respective role of antithrombin III and heparin cofactor II in the in vitro anticoagulant effect of heparin and of various sulphated polysaccharides
Abstract
The in vitro anticoagulant effects of standard heparin (SH) and of seven other sulphated polysaccharides (SPS) were investigated by measuring activated partial thromboplastin time (APTT) prolongation of normal plasma and of plasmas selectively depleted of antithrombin III (AT III), of heparin cofactor II (HC II) and of both heparin cofactors. This allowed the determination of the relative contribution of each of the two heparin cofactors to the …
Authors
Sie P; Ofosu F; Fernandez F; Buchanan MR; Petitou M; Boneu B
Journal
British Journal of Haematology, Vol. 64, No. 4, pp. 707–714
Publisher
Wiley
Publication Date
December 1986
DOI
10.1111/j.1365-2141.1986.tb02232.x
ISSN
0007-1048