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EXPERIMENTAL PRODUCTION OF MICROANGIOPATHIC...
Journal article

EXPERIMENTAL PRODUCTION OF MICROANGIOPATHIC HÆMOLYTIC ANÆMIA IN VIVO

Abstract

Prolonged hæmolysis with red-cell fragmentation followed the production of acute defibrination in rabbits in which the fibrinolytic system had been inhibited. Red blood-cells adhered to fibrin strands within the blood and attached to the bloodvessels of these rabbits. It is suggested that hæmolysis and red-blood-cell fragmentation are brought about by the continuing interaction of red blood-cells and fibrin within the circulation, and that a …

Authors

Rubenberg ML; Bull BS; Regoeczi E; Dacie JV; Brain MC

Journal

The Lancet, Vol. 290, No. 7526, pp. 1121–1123

Publisher

Elsevier

Publication Date

November 1967

DOI

10.1016/s0140-6736(67)90622-8

ISSN

0140-6736