Journal article
Effect of Warfarin on Activated Partial Thromboplastin Time in Patients Receiving Heparin
Abstract
BACKGROUND: The activated partial thromboplastin time (APTT) is used to adjust heparin sodium dosage. However, warfarin sodium is often administered concomitantly with heparin and may also affect the APTT and, therefore, heparin dose. We performed a prospective cohort study to quantify the effect of warfarin on the APTT in patients who are being treated with heparin.
METHODS: Serial assays of APTT, international normalized ratio, heparin …
Authors
Kearon C; Johnston M; Moffat K; McGinnis J; Ginsberg JS
Journal
JAMA Internal Medicine, Vol. 158, No. 10, pp. 1140–1143
Publisher
American Medical Association (AMA)
Publication Date
May 25, 1998
DOI
10.1001/archinte.158.10.1140
ISSN
2168-6106