Hemostatic efficacy of pathogen-inactivated vs untreated platelets: a randomized controlled trial Journal Articles

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abstract

Key PointsPathogen-inactivated platelets were noninferior in preventing bleeding only in intention-to-treat analysis. In contrast to animal models, alloimmunization could not be prevented when using pathogen-inactivated platelets.

authors

van der Meer, Pieter F
Ypma, Paula F
van Geloven, Nan
van Hilten, Joost A
van Wordragen-Vlaswinkel, Rinie J
Eissen, Okke
Zwaginga, Jaap J
Trus, Michael
Beckers, Erik AM
te Boekhorst, Peter
Tinmouth, Alan
Lin, Yulia
Hsia, Cyrus
Lee, David
Norris, Philip J
Goodrich, Raymond P
Brand, Anneke
Hervig, Tor
Heddle, Nancy
van der Bom, Johanna G
Kerkhoffs, Jean-Louis H

status

published

publication date

July 12, 2018

has subject area

1102 Cardiorespiratory Medicine and Haematology (FoR)
1103 Clinical Sciences (FoR)
1114 Paediatrics and Reproductive Medicine (FoR)
Blood Coagulation (MeSH)
Blood Platelets (MeSH)
Female (MeSH)
Hemostasis (MeSH)
Humans (MeSH)
Immunology (Science Metrix)
Kaplan-Meier Estimate (MeSH)
Male (MeSH)
Multicenter Studies as Topic (MeSH)
Patient Outcome Assessment (MeSH)
Platelet Function Tests (MeSH)
Platelet Transfusion (MeSH)
Randomized Controlled Trials as Topic (MeSH)

published in

Blood Journal