Journal article
Mice with deleted multimerin 1 and α-synuclein genes have impaired platelet adhesion and impaired thrombus formation that is corrected by multimerin 1
Abstract
BACKGROUND: Multimerin 1 is a stored platelet and endothelial cell adhesive protein that shows significant conservation. In vitro, multimerin 1 supports platelet adhesion and it also binds to collagen and enhances von Willebrand factor-dependent platelet adhesion to collagen. As selective, multimerin 1 deficient mice have not been generated, we investigated multimerin 1 effects on platelet adhesion using a subpopulation of C57BL/6J mice with …
Authors
Reheman A; Tasneem S; Ni H; Hayward CPM
Journal
Thrombosis Research, Vol. 125, No. 5, pp. e177–e183
Publisher
Elsevier
Publication Date
May 2010
DOI
10.1016/j.thromres.2010.01.009
ISSN
0049-3848