Journal article
Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran-induced anticoagulation
Abstract
Dabigatran is effective in decreasing the risk of ischaemic stroke in patients with atrial fibrillation. However, like all anticoagulants, it is associated with a risk of bleeding. In cases of trauma or emergency surgery, emergency reversal of dabigatran-induced anticoagulation may be required. A specific reversal agent for dabigatran, idarucizumab, has been approved by the US Food and Drug Administration. Alternative reversal agents are …
Authors
Grottke O; Aisenberg J; Bernstein R; Goldstein P; Huisman MV; Jamieson DG; Levy JH; Pollack CV; Spyropoulos AC; Steiner T
Journal
Critical Care, Vol. 20, No. 1,
Publisher
Springer Nature
Publication Date
12 2016
DOI
10.1186/s13054-016-1275-8
ISSN
1364-8535