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Leukocyte-versus microparticle-mediated tissue...
Journal article

Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development

Abstract

Circulating tissue factor accumulates in the developing thrombus and contributes to fibrin clot formation. To determine whether tissue factor derived from hematopoietic cells is delivered to the thrombus via tissue factor-bearing microparticles or circulating leukocytes expressing tissue factor on the plasma membrane, we compared the kinetics of tissue factor accumulation in the developing arteriolar thrombus with the time course of …

Authors

Gross PL; Furie BC; Merrill-Skoloff G; Chou J; Furie B

Journal

Journal of Leukocyte Biology, Vol. 78, No. 6, pp. 1318–1326

Publisher

Oxford University Press (OUP)

Publication Date

October 4, 2005

DOI

10.1189/jlb.0405193

ISSN

0741-5400