Journal article
Real‐world variability in dabigatran levels in patients with atrial fibrillation
Abstract
BACKGROUND: In clinical practice, physicians are given the choice of selecting one of two dabigatran doses based on patient characteristics, with the lower dose typically used in patients at a higher risk of bleeding.
OBJECTIVES: The objectives of the study were to (i) estimate the inter- and intra-patient variability in dabigatran levels with 110 mg (DE110) and 150 mg (DE150) doses, (ii) examine the effect of physicians' dose selection on …
Authors
Chan NC; Coppens M; Hirsh J; Ginsberg JS; Weitz JI; Vanassche T; Douketis JD; Schulman S; Eikelboom JW
Journal
Journal of Thrombosis and Haemostasis, Vol. 13, No. 3, pp. 353–359
Publisher
Elsevier
Publication Date
3 2015
DOI
10.1111/jth.12823
ISSN
1538-7933