Journal article
The APTT Response of Pregnant Plasma to Unfractionated Heparin1
Abstract
Pregnancy is associated with a physiological increase in coagulation factors and heparin binding proteins; both can affect the activated partial thromboplastin time (APTT) in response to unfractionated heparin (UFH) invalidating the use of a non-pregnant APTT therapeutic range. We compared the anticoagulant response of UFH added in vitro to the plasma of 13 pregnant (third trimester) and 15 nonpregnant women to determine whether the measured …
Authors
Chunilal SD; Young E; Johnston MA; Robertson C; Naguit I; Stevens P; Galashan D; Oskamp ML; Brennan B; Ginsberg JS
Journal
Thrombosis and Haemostasis, Vol. 87, No. 01, pp. 92–97
Publisher
Thieme
Publication Date
2002
DOI
10.1055/s-0037-1612949
ISSN
0340-6245