Journal article
Clopidogrel does not suppress blood markers of coagulation activation in aspirin-treated patients with non-ST-elevation acute coronary syndromes
Abstract
AIMS: The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) Study demonstrated that clopidogrel plus aspirin was superior to aspirin alone for prevention of recurrent vascular events in patients with acute coronary syndromes. The aim of this study was to compare the effect of these two regimens on biochemical markers of platelet and coagulation activation.
METHODS AND RESULTS: We studied 485 patients with non-ST-elevation acute …
Authors
Eikelboom JW; Weitz JI; Budaj A; Zhao F; Copland I; Maciejewski P; Johnston M; Yusuf S
Journal
European Heart Journal, Vol. 23, No. 22, pp. 1771–1779
Publisher
Oxford University Press (OUP)
Publication Date
November 15, 2002
DOI
10.1053/euhj.2000.3234
ISSN
0195-668X
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AntigensAspirinBiomarkersBlood CoagulationBlood Coagulation FactorsClopidogrelCohort StudiesCoronary DiseaseDrug Therapy, CombinationFemaleFibrin Fibrinogen Degradation ProductsHumansMaleMiddle AgedP-SelectinPlatelet Activating FactorPlatelet ActivationPlatelet Aggregation InhibitorsTiclopidineTreatment Outcomevon Willebrand Factor