Journal article
Dabigatran etexilate and reduction in serum apolipoprotein B
Abstract
OBJECTIVE: Carboxylesterases, which convert dabigatran etexilate to its active form, dabigatran, have also been shown to influence lipoprotein metabolism, although any pleotropic effects of the drug based on this possible mechanism has not been evaluated. We examined the effects of dabigatran etexilate on serum lipoprotein markers in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) study.
METHODS: 2513 participants from …
Authors
Joseph P; Pare G; Wallentin L; Connolly S; Yusuf S; Wang J; Ezekowitz M; Eikelboom J; Siegbahn A; Reilly P
Journal
Heart, Vol. 102, No. 1,
Publisher
BMJ
Publication Date
January 1, 2016
DOI
10.1136/heartjnl-2015-307586
ISSN
1355-6037