The influence of drugs upon the anticoagulant activity of heparin. Journal Articles

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abstract

Although physical incompatibility between heparin and a number of drugs has been reported we did not discover any evidence of such incompatibility when heparin was mixed with 11 commonly used drugs in therapeutic concentrations.Furthermore, there was no detectable change in the anticoagulant activity in the presence of any of these drugs, nor was there any change in the biological activity of the antibiotics tested.

authors

Hodby, ED
Hirsh, Jack
Adeniyi-Jones, C

status

published

publication date

March 4, 1972

has subject area

11 Medical and Health Sciences (FoR)
Ampicillin (MeSH)
Anti-Bacterial Agents (MeSH)
Ascorbic Acid (MeSH)
Blood Coagulation (MeSH)
Blood Coagulation Tests (MeSH)
Cephalothin (MeSH)
Cloxacillin (MeSH)
Drug Interactions (MeSH)
General & Internal Medicine (Science Metrix)
Heparin (MeSH)
Humans (MeSH)
Hydrocortisone (MeSH)
Hydrogen-Ion Concentration (MeSH)
In Vitro Techniques (MeSH)
Isoproterenol (MeSH)
Lidocaine (MeSH)
Microbial Sensitivity Tests (MeSH)
Penicillin G (MeSH)
Potassium Chloride (MeSH)
Succinates (MeSH)
Tetracycline (MeSH)
Vitamin B Complex (MeSH)

published in

CANADIAN MEDICAL ASSOCIATION JOURNAL Journal