Journal article
The effect of aspirin inhibition of PGI2 production on platelet adherence to normal and damaged rabbit aortae
Abstract
These experiments were designed to investigate whether or not PGI2 production by vessel walls is responsible for their non-thrombogenic property. Adherence of rabbit platelets to the endothelium and sub-endothelium of the rabbit aorta was studied in vitro and in vivo when PGI2 production by the vessel wall was inhibited by aspirin. For in vitro studies, everted segments of rabbit aorta were mounted on a probe and rotated in a suspension of …
Authors
Dejana E; Cazenave J-P; Groves HM; Kinlough-Rathbone RL; Richardson M; Packham MA; Mustard JF
Journal
Thrombosis Research, Vol. 17, No. 3-4, pp. 453–464
Publisher
Elsevier
Publication Date
February 1980
DOI
10.1016/0049-3848(80)90080-8
ISSN
0049-3848