Disease Progression Concept

subject area of

• <p>Cost-Effectiveness Of Once-Daily Single-Inhaler Triple Therapy In COPD: The IMPACT Trial</p>  Academic Article
• <p>Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review</p>  Academic Article
• <p>Long-term cost and utility consequences of short-term clinically important deterioration in patients with chronic obstructive pulmonary disease: results from the TORCH study</p>  Academic Article
• 2016 Addendum to the Canadian Guidelines for the Management of Plaque Psoriasis 2009  Academic Article
• 45-Years Between Skin Lesions and CNS Symptoms in a Patient with Scleroderma  Academic Article
• BRAF-KIAA1549 Fusion Predicts Better Clinical Outcome in Pediatric Low-Grade Astrocytoma  Academic Article
• AMPK β1 reduces tumor progression and improves survival in p53 null mice  Academic Article
• HIVvirological rebounds but not blips predict liver fibrosis progression in antiretroviral‐treatedHIV/hepatitisCvirus‐coinfected patients  Academic Article
• A Clinical Prediction Model to Stratify Retinopathy of Prematurity Risk Using Postnatal Weight Gain  Academic Article
• A Clinical Study of Migraine Evolution  Academic Article
• A Comparison of the Health Utilities Indices Mark 2 and Mark 3 in Type 2 Diabetes  Academic Article
• A Longitudinal, Population-Based, Cohort Study of Childhood Asthma Followed to Adulthood  Academic Article
• A Multicenter Open-Label Study to Assess the Safety of a New Formulation of BLP25 Liposome Vaccine in Patients With Unresectable Stage III Non–Small-Cell Lung Cancer  Academic Article
• A Multidimensional Approach to the Management of Severe Asthma: Inflammometry, Molecular Microbiology and Bronchial Thermoplasty  Academic Article
• A Nurse-coordinated Model of Care versus Usual Care for Stage 3/4 Chronic Kidney Disease in the Community  Academic Article
• A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration-resistant Prostate Cancer: Canadian Cancer Trials Group Study IND205  Academic Article
• A Phase II Study of Pazopanib in Patients with Recurrent or Metastatic Invasive Breast Carcinoma: A Trial of the Princess Margaret Hospital Phase II Consortium  Academic Article
• A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer  Academic Article
• A Phase II Trial with Pharmacodynamic Endpoints of the Proteasome Inhibitor Bortezomib in Patients with Metastatic Colorectal Cancer  Academic Article
• A Phase II study of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) and gemcitabine in advanced pancreatic carcinoma. A trial of the Princess Margaret Hospital Phase II consortium  Academic Article
• A Practical Guide for Treatment of Rapidly Progressive ADPKD with Tolvaptan  Academic Article
• A Protocol for a Pan-Canadian Prospective Observational Study on Active Surveillance or Surgery for Very Low Risk Papillary Thyroid Cancer  Academic Article
• A Randomized Controlled Trial of Caries Prevention in Dental Practice  Academic Article
• A Review of Physical Activity and Circulating miRNA Expression: Implications in Cancer Risk and Progression  Academic Article
• A cluster-based analysis evaluating the impact of comorbidities in fibrotic interstitial lung disease  Academic Article
• A community randomized controlled clinical trial of mixed carotenoids and micronutrient supplementation of patients with acquired immunodeficiency syndrome  Academic Article
• A double-blind, randomized controlled trial to compare the effect of biannual peripheral magnetic resonance imaging, radiography and standard of care disease progression monitoring on pharmacotherapeutic escalation in rheumatoid and undifferentiated inflammatory arthritis: study protocol for a randomized controlled trial  Academic Article
• A longitudinal study of the pathophysiological changes in single human thenar motor units in amyotrophic lateral sclerosis  Academic Article
• A meta-analysis and systematic review of thalidomide for patients with previously untreated multiple myeloma  Academic Article
• A multicentric phase II clinical trial on intra-arterial hepatic radiotherapy with 90yttrium SIR-spheres in unresectable, colorectal liver metastases refractory to i.v. chemotherapy: preliminary results on toxicity and response rates.  Academic Article
• A new era in idiopathic pulmonary fibrosis: considerations for future clinical trials  Academic Article
• A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease  Academic Article
• A novel homozygous GALC mutation: Very early onset and rapidly progressive Krabbe disease  Academic Article
• A novel take on idiopathic pulmonary fibrosis disease progression: localised autoimmunity  Academic Article
• A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: a study of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG IND.168)  Academic Article
• A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas  Conference Paper
• A phase II study of PS-341 (Bortezomib) in advanced or metastatic urothelial cancer. A trial of the Princess Margaret Hospital and University of Chicago phase II consortia  Academic Article
• A phase II study of SB939, a novel pan-histone deacetylase inhibitor, in patients with translocation-associated recurrent/metastatic sarcomas—NCIC-CTG IND 200  Academic Article
• A phase II study of cediranib (AZD 2171) in treatment naive patients with progressive unresectable recurrent or metastatic renal cell carcinoma. A trial of the PMH phase 2 consortium  Academic Article
• A phase II study of doxorubicin/paclitaxel plus G-CSF for metastatic breast cancer.  Academic Article
• A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial  Academic Article
• A phase II study of obatoclax mesylate, a Bcl-2 antagonist, plus topotecan in relapsed small cell lung cancer  Academic Article
• A phase II study of perifosine (D-21226) in patients with previously untreated metastatic or locally advanced soft tissue sarcoma: A National Cancer Institute of Canada Clinical Trials Group trial  Academic Article
• A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer  Academic Article
• A phase II trial of dovitinib in previously-treated advanced pleural mesothelioma: The Ontario Clinical Oncology Group  Academic Article
• A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis  Academic Article
• A pragmatic single-blind randomised controlled trial and economic evaluation of the use of leukotriene receptor antagonists in primary care at steps 2 and 3 of the national asthma guidelines (ELEVATE study).  Academic Article
• A radiation-induced adaptive response prolongs the survival of prion-infected mice  Academic Article
• A randomized placebo-controlled study of tamoxifen after adjuvant chemotherapy in premenopausal women with early breast cancer (National Cancer Institute of Canada—Clinical Trials Group Trial, MA.12)  Academic Article
• A realist review to understand the efficacy and outcomes of interventions designed to minimise, reverse or prevent the progression of frailty  Academic Article
• A role for sensory nerves in the late asthmatic response  Academic Article
• A role for the TGFβ-Par6 polarity pathway in breast cancer progression  Academic Article
• A stochastic approach to risk management for prostate cancer patients on active surveillance  Academic Article
• A stochastic model for survival of early prostate cancer with adjustments for leadtime, length bias, and over‐detection  Academic Article
• A systematic review on how patients value chronic obstructive pulmonary disease outcomes  Academic Article
• A viscerally driven cachexia syndrome in patients with advanced colorectal cancer: contributions of organ and tumor mass to whole-body energy demands  Academic Article
• ABC 1 (1st International consensus guidelines for advanced breast cancer): A positive step  Academic Article
• ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer  Academic Article
• ADAMTS-13 may not predict disease or outcome in patients with Thrombotic Thrombocytopenic Purpura  Academic Article
• AGA Technical Review on Gastric Intestinal Metaplasia—Natural History and Clinical Outcomes  Academic Article
• APOL1 Genotype and Renal Function of Black Living Donors  Academic Article
• ARDS in patients with thermal injury  Academic Article
• Abiraterone acetate for patients with metastatic castration-resistant prostate cancer progressing after chemotherapy: final analysis of a multicentre, open-label, early-access protocol trial  Academic Article
• Absence of renal sequelae after childhood Escherichia coli O157:H7 gastroenteritis  Academic Article
• Accumulated Delivered Dose Response of Stereotactic Body Radiation Therapy for Liver Metastases  Academic Article
• Activin mRNA induced during amygdala kindling shows a spatiotemporal progression that tracks the spread of seizures  Academic Article
• Activity of fulvestrant in HER2-overexpressing advanced breast cancer  Academic Article
• Acute Precipitants of Congestive Heart Failure Exacerbations  Academic Article
• Acute change in glomerular filtration rate with inhibition of the renin-angiotensin system does not predict subsequent renal and cardiovascular outcomes  Academic Article
• Acute exacerbation of idiopathic pulmonary fibrosis: international survey and call for harmonisation  Academic Article
• Acute exacerbations of progressive-fibrosing interstitial lung diseases  Academic Article
• Advanced Chronic Kidney Disease in Lupus Nephritis: Is Dialysis Inevitable?  Academic Article
• Akt isoform specific effects in ovarian cancer progression  Academic Article
• Aldehyde dehydrogenase 3A1 associates with prostate tumorigenesis  Academic Article
• All-cause hospitalizations in systemic lupus erythematosus from a large Canadian referral centre  Academic Article
• Altered neuroendocrine status at the onset of CNS lupus-like disease  Academic Article
• American Society of Clinical Oncology/American Society of Hematology Clinical Practice Guideline Update on the Use of Epoetin and Darbepoetin in Adult Patients With Cancer  Academic Article
• American Society of Hematology/American Society of Clinical Oncology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer  Academic Article
• Amoxicillin for acute lower respiratory tract infection in primary care: subgroup analysis by bacterial and viral aetiology  Academic Article
• Amoxicillin for acute lower respiratory tract infection in primary care: subgroup analysis of potential high-risk groups  Academic Article
• Amplification of MUC1 in prostate cancer metastasis and CRPC development  Academic Article
• Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer  Academic Article
• An Optimized Clinical Regimen for the Oncolytic Virus PV701  Academic Article
• An Updated Systematic Review and Commentary Examining the Effectiveness of Radioactive Iodine Remnant Ablation in Well-Differentiated Thyroid Cancer  Academic Article
• An atypical presentation of giant cell arteritis  Academic Article
• Analysis of the Contribution of Salmonella Pathogenicity Islands 1 and 2 to Enteric Disease Progression Using a Novel Bovine Ileal Loop Model and a Murine Model of Infectious Enterocolitis  Academic Article
• Androgen therapy in inherited bone marrow failure syndromes: analysis from the Canadian Inherited Marrow Failure Registry  Academic Article
• Angiographic Disease Progression and Residual Risk of Cardiovascular Events While on Optimal Medical Therapy  Academic Article
• Angiotensin Blockade Does Not Affect Fibrosis Progression in Recurrent Hepatitis C After Liver Transplantation  Academic Article
• Animal models of COPD: What do they tell us?  Academic Article
• Animal models of pulmonary fibrosis: how far from effective reality?  Academic Article
• Antacid Therapy and Disease Progression in Patients with Idiopathic Pulmonary Fibrosis Who Received Pirfenidone  Academic Article
• Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis  Academic Article
• Antacid therapy in idiopathic pulmonary fibrosis: more questions than answers?  Academic Article
• Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for people with asthma  Academic Article
• Antiretroviral effects on HIV-1 RNA, CD4 cell count and progression to AIDS or death: a meta-regression analysis  Academic Article
• Antiretroviral resistance testing in HIV-positive people  Academic Article
• Anxiety in youth at clinical high risk for psychosis: A case study and conceptual model  Academic Article
• ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis  Academic Article
• Application of new acute kidney injury biomarkers in human randomized controlled trials  Academic Article
• Applying contemporary antithrombotic therapy in the secondary prevention of chronic atherosclerotic cardiovascular disease  Academic Article
• Approach to the detection and management of chronic kidney disease: What primary care providers need to know.  Academic Article
• Areas of controversy in neuroprogression in bipolar disorder  Academic Article
• Assessing sensitivity to change: choosing the appropriate change coefficient  Academic Article
• Assessing the Educational Needs of Canadian Gastroenterologists and Gastroenterology Nurses: Challenges to Optimal Care in Crohn’s Disease  Academic Article
• Assessing the Reliability of a Semiautomated Segmentation Algorithm for Quantifying Erosions in the Metacarpophalangeal Joints of Patients with Rheumatoid Arthritis  Academic Article
• Assessment of biochemical recurrence of prostate cancer (Review)  Academic Article
• Assessment on the Prevention of Progression by Rosiglitazone on Atherosclerosis in diabetes patients with Cardiovascular History (APPROACH): Study design and baseline characteristics  Academic Article
• Association Between RECIST Changes and Survival in Patients with Metastatic Castration-resistant Prostate Cancer Receiving Docetaxel  Academic Article
• Association between older age and adverse outcomes on antiretroviral therapy  Academic Article
• Association between progression-free survival and health-related quality of life in oncology: a systematic review protocol  Academic Article
• Association of Clonal Hematopoiesis of Indeterminate Potential with Worse Kidney Function and Anemia in Two Cohorts of Patients with Advanced Chronic Kidney Disease  Academic Article
• Association of Delirium With Cognitive Decline in Late Life  Academic Article
• Association of Gastroesophageal Factors and Worsening of Forced Vital Capacity in Systemic Sclerosis  Academic Article
• Association of Intermittent and Constant Knee Pain Patterns With Knee Pain Severity and With Radiographic Knee Osteoarthritis Duration and Severity  Academic Article
• Association of Low-Dose Colchicine With Incidence of Knee and Hip Replacements  Academic Article
• Association of Multiple Cellular Stress Pathways With Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-Deficient Mice  Academic Article
• Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals  Academic Article
• Association of Patient Age With Progression of Low-risk Papillary Thyroid Carcinoma Under Active Surveillance  Academic Article
• Association of Proteinuria and Incident Atrial Fibrillation in Patients With Intact and Reduced Kidney Function  Academic Article
• Association of dose escalation of octreotide long‐acting release on clinical symptoms and tumor markers and response among patients with neuroendocrine tumors  Academic Article
• Association of interleukin-10 levels with age of onset and duration of illness in patients with major depressive disorder  Academic Article
• Association of renin–angiotensin and endothelial nitric oxide synthase gene polymorphisms with blood pressure progression and incident hypertension: prospective cohort study  Academic Article
• Associations Between Childhood Cognition and Cardiovascular Events in Adulthood: A Systematic Review and Meta-analysis  Academic Article
• Associations with Post-Consultation Health-Status in Primary Care Managed Acute Exacerbation of COPD  Academic Article
• Asthma Worsenings: Approaches to Prevention and Management from the Asthma Worsenings Working Group  Academic Article
• Asthma progression and mortality: the role of inhaled corticosteroids  Academic Article
• Atopic March: Collegium Internationale Allergologicum Update 2020  Academic Article
• Atypical Polycystic Kidney Disease as defined by Imaging  Academic Article
• Atypical clinical course in juvenile metachromatic leukodystrophy involving novel arylsulfatase A gene mutations  Academic Article
• Autoantibodies and immune complexes to oxidation-specific epitopes and progression of aortic stenosis: Results from the ASTRONOMER trial  Academic Article
• Autobiographical Memory and Patterns of Brain Atrophy in Fronto-temporal Lobar Degeneration  Academic Article
• Autoimmune heparin‐induced thrombocytopenia and venous limb gangrene after aortic dissection repair: in vitro and in vivo effects of intravenous immunoglobulin  Academic Article
• B Vitamins and Magnetic Resonance Imaging–Detected Ischemic Brain Lesions in Patients With Recent Transient Ischemic Attack or Stroke  Academic Article
• Bacteria Challenge in Smoke-exposed Mice Exacerbates Inflammation and Skews the Inflammatory Profile  Academic Article
• Balance Measures Over 12 Months in Individuals With Chronic Obstructive Pulmonary Disease  Academic Article
• Barrett's Oesophagus Surveillance versus endoscopy at need Study (BOSS): protocol and analysis plan for a multicentre randomized controlled trial  Academic Article
• Being careful: A grounded theory of emergent chronic knee problems  Academic Article
• Beneficial effect of ginseng root in SOD-1 (G93A) transgenic mice  Academic Article
• Benralizumab for Prednisone-Dependent Eosinophilic Asthma Associated With Novel STAT3 Loss of Function Mutation  Academic Article
• Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial  Academic Article
• Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways  Academic Article
• Beyond the year 2000 in CHD research: current understanding of the cellular mechanism of atherosclerosis.  Academic Article
• Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2  Academic Article
• Biomarkers Predict Progression of Acute Kidney Injury after Cardiac Surgery  Academic Article
• Biomarkers of neuroprogression and late staging in bipolar disorder: A systematic review  Academic Article
• Biotinidase is a Novel Marker for Papillary Thyroid Cancer Aggressiveness  Academic Article
• Blood eosinophil count, a marker of inhaled corticosteroid effectiveness in preventing COPD exacerbations in post-hoc RCT and observational studies: systematic review and meta-analysis  Academic Article
• Body mass index and chronic kidney disease outcomes after acute kidney injury: a prospective matched cohort study  Academic Article
• Bone markers and their prognostic value in metastatic bone disease: Clinical evidence and future directions  Academic Article
• Brain-derived neurotrophic factor, impaired glucose metabolism, and bipolar disorder course  Academic Article
• Burden of Disease in Patients with Mild or Mild-to-Moderate Chronic Obstructive Pulmonary Disease (Global Initiative for Chronic Obstructive Lung Disease Group A or B): A Systematic Literature Review  Academic Article
• Burden of carotid artery atherosclerosis in Chinese adults: Implications for future risk of cardiovascular diseases  Academic Article
• C-Reactive Protein for Antibiotic Use in COPD Exacerbations  Academic Article
• COPD exacerbations in the emergency department: Epidemiology and related costs. A retrospective cohort multicentre study from the Italian Society of Emergency Medicine (SIMEU)  Academic Article
• COPD profiles and treatable traits using minimal resources: identification, decision tree and stability over time  Academic Article
• CT Angiography “Spot Sign” Predicts Hematoma Expansion in Acute Intracerebral Hemorrhage  Academic Article
• Cabozantinib for Progressive Metastatic Castration-resistant Prostate Cancer Following Docetaxel: Combined Analysis of Two Phase 3 Trials  Academic Article
• Can We Predict Exacerbations of Asthma?  Academic Article
• Canadian Consensus: Oligoprogressive, Pseudoprogressive, and Oligometastatic Non-Small-Cell Lung Cancer  Academic Article
• Canadian Helicobacter Study Group Consensus Conference: Update on the Management ofHelicobacter pylori- An Evidence-Based Evaluation of Six Topics Relevant to Clinical Outcomes in Patients Evaluated forH pyloriInfection  Academic Article
• Canadian Ophthalmological Society evidence-based clinical practice guidelines for the periodic eye examination in adults in Canada.  Academic Article
• Canadian expert consensus: optimal treatment of neovascular age-related macular degeneration  Academic Article
• Cancer-Induced Oxidative Stress and Pain  Academic Article
• Cardiovascular Safety Of Nintedanib In Subgroups By Cardiovascular Risk At Baseline In The Tomorrow And Inpulsis Trials  Conference Paper
• Case 216: Hypertrophic Spinal Pachymeningitis  Academic Article
• Cerebral Microbleeds and the Effect of Intensive Blood Pressure Reduction on Hematoma Expansion and Functional Outcomes  Academic Article
• Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function  Academic Article
• Challenges and developments in research of the early stages of bipolar disorder  Academic Article
• Change in bone mineral density as a function of age in women and men and association with the use of antiresorptive agents  Academic Article
• Changes in skin score in early diffuse cutaneous systemic sclerosis are associated with changes in global disease severity  Academic Article
• Changes in the aortic endothelium and plasma von Willebrand factor levels during the onset and progression of insulin-dependent diabetes in BB rats  Academic Article
• Changing the bipolar illness trajectory  Academic Article
• Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study  Academic Article
• Characterization of human embryonic stem cells with features of neoplastic progression  Academic Article
• Chiari malformation and tuberculous meningitis: aetiology and management  Academic Article
• Childhood primary angiitis of the central nervous system: Identifying disease trajectories and early risk factors for persistently higher disease activity  Academic Article
• Circulating Angiopoietin-2 as a Biomarker in ANCA-Associated Vasculitis  Academic Article
• Circulating Levels of Matrix Gla Protein and Progression of Aortic Stenosis: A Substudy of the Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) Trial  Academic Article
• Classifying kidney problems: can we avoid framing risks as diseases?  Academic Article
• Clinical Decision-Making Tool for Safe and Effective Prescription of Exercise in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Results From an Interdisciplinary Delphi Survey and Focus Groups  Academic Article
• Clinical Impact of Residual Extraretroperitoneal Masses in Patients With Advanced Nonseminomatous Germ Cell Testicular Cancer  Academic Article
• Clinical Insights into Pulmonary Exacerbations in Cystic Fibrosis from the Microbiome. What Are We Missing?  Academic Article
• Clinical Manifestations Associated With the N-Terminal-Acetyltransferase NAA10 Gene Mutation in a Girl: Ogden Syndrome  Academic Article
• Clinical Staging in Bipolar Disorder  Academic Article
• Clinical Trial Considerations in Developing Treatments for Early Stages of Common, Chronic Kidney Diseases: A Scientific Workshop Cosponsored by the National Kidney Foundation and the US Food and Drug Administration  Conference Paper
• Clinical Utility of Biochemical Markers of Bone Metabolism for Improving the Management of Patients with Advanced Multiple Myeloma  Academic Article
• Clinical and biological implications of driver mutations in myelodysplastic syndromes  Academic Article
• Clinical and pathological findings of SARS-CoV-2 infection and concurrent IgA nephropathy: a case report  Academic Article
• Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer  Academic Article
• Clinical course and treatment of incidentally detected splanchnic vein thrombosis: an individual patient data meta-analysis  Academic Article
• Clinical implications and characterization of Group A Streptoccoccus infections in adults with cystic fibrosis  Academic Article
• Clinical implications of a staging model for bipolar disorders  Academic Article
• Clinical outcome following post-chemotherapy retroperitoneal lymph node dissection in men with intermediate- and poor-risk nonseminomatous germ cell tumour  Academic Article
• Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value  Academic Article
• Clonal Hematopoiesis of Indeterminate Potential and Kidney Function Decline in the General Population  Academic Article
• Clusters in Short-term Disease Course in Participants With Primary Dupuytren Disease  Academic Article
• Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas  Academic Article
• Cocaine/crack use is not associated with fibrosis progression measured by AST-to-Platelet Ratio Index in HIV-HCV co-infected patients: a cohort study  Academic Article
• Cohort Profile: The Canadian HIV-Hepatitis C Co-infection Cohort Study  Academic Article
• Colchicine and aspirin in community patients with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial  Academic Article
• Colchicine and the combination of rivaroxaban and aspirin in patients hospitalised with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial  Academic Article
• Colds as predictors of the onset and severity of COPD exacerbations  Academic Article
• Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer  Academic Article
• Combining Gemcitabine and Capecitabine in Patients With Advanced Biliary Cancer: A Phase II Trial  Conference Paper
• Comparative diagnostic accuracy of knee adduction moments in knee osteoarthritis: A case for not normalizing to body size  Academic Article
• Comparing the Health Utilities Index Mark 3 (HUI3) with the Short Form-36 Preference-Based SF-6D in Chronic Kidney Disease  Academic Article
• Comparing virtual with conventional microscopy for the consensus diagnosis of Barrett’s neoplasia in the AspECT Barrett’s chemoprevention trial pathology audit  Academic Article
• Comparison between conventional and "clinical" assessment of experimental lung fibrosis  Academic Article
• Comparison of Echocardiographic and Cardiac Magnetic Resonance Imaging for Assessing Right Ventricular Function in Adults With Repaired Tetralogy of Fallot  Academic Article
• Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism  Academic Article
• Comparison of the effects of secondary prevention in schoolchildren between hospitals with and without mobile dental services in Southern Thailand  Academic Article
• Comprehensive Care Management in Conjunction with Sputum Cytometry-Guided Pharmacotherapy in a Post-Discharge Clinic for Patients with COPD  Academic Article
• Comprehensive Plasma Metabolomic Analyses of Atherosclerotic Progression Reveal Alterations in Glycerophospholipid and Sphingolipid Metabolism in Apolipoprotein E-deficient Mice  Academic Article
• Concerning: “The sad plight of multiple sclerosis research (low on fact, high on fiction): critical data to support it being a neurocristopathy” by Peter O. Behan and Abhijit Chaudhuri  Academic Article
• Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression.  Academic Article
• Consensus Statements for Management of Barrett's Dysplasia and Early-Stage Esophageal Adenocarcinoma, Based on a Delphi Process  Academic Article
• Consensus on nomenclature for clinical staging models in bipolar disorder: A narrative review from the International Society for Bipolar Disorders (ISBD) Staging Task Force  Academic Article
• Construct validity of the RAND-12 and Health Utilities Index Mark 2 and 3 in type 2 diabetes  Academic Article
• Contactin-1 Reduces E-Cadherin Expression Via Activating AKT in Lung Cancer  Academic Article
• Correlates of decline in gross motor capacity in adolescents with cerebral palsy in Gross Motor Function Classification System levels III to V: an exploratory study  Academic Article
• Correlation of hypointensities in susceptibility-weighted images to tissue histology in dementia patients with cerebral amyloid angiopathy: a postmortem MRI study  Academic Article
• Correlations between plasma homocysteine and folate concentrations and carotid atherosclerosis in high-risk individuals: baseline data from the Homocysteine and Atherosclerosis Reduction Trial (HART)  Academic Article
• Cost effectiveness of highly active antiretroviral therapy in HIV-infected patients  Academic Article
• Cost implications of the use of basal insulin glargine in people with early dysglycemia: The ORIGIN trial  Academic Article
• Cost-Effectiveness Analysis of a Randomized Trial Comparing Care Models for Chronic Kidney Disease  Academic Article
• Cost-Effectiveness of the Aerobika® Oscillating Positive Expiratory Pressure Device in the Management of Chronic Obstructive Pulmonary Disease Exacerbations in Canada  Academic Article
• Cost-effectiveness of umeclidinium as add-on to ICS/LABA therapy in COPD: A UK perspective  Academic Article
• Critically Ill Patients With Severe Acute Respiratory Syndrome  Academic Article
• Crosstalk between the Unfolded Protein Response and NF-κB-Mediated Inflammation in the Progression of Chronic Kidney Disease  Academic Article
• Current management of advanced and castration resistant prostate cancer.  Academic Article
• Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial  Academic Article
• DElaying Disease Progression In COPD with Early Initiation of Dual Bronchodilator or Triple Inhaled PharmacoTherapy (DEPICT): A Predictive Modelling Approach  Academic Article
• DO IT Trial: vitamin D Outcomes and Interventions in Toddlers –a TARGet Kids! randomized controlled trial  Academic Article
• Deep vein thrombosis: update on diagnosis and management  Academic Article
• Derivation and External Validation of Prediction Models for Advanced Chronic Kidney Disease Following Acute Kidney Injury  Academic Article
• Design of the INPULSIS™ trials: Two phase 3 trials of nintedanib in patients with idiopathic pulmonary fibrosis  Academic Article
• Designing a Rational Follow-Up Schedule for Patients with Extremity Soft Tissue Sarcoma  Academic Article
• Detecting prodromal Alzheimer's disease in mild cognitive impairment: utility of the CAMCOG and other neuropsychological predictors  Academic Article
• Detection and Early Referral of Patients With Interstitial Lung Abnormalities  Academic Article
• Detection of COPD Exacerbations and Compliance With Patient-Reported Daily Symptom Diaries Using a Smartphone-Based Information System  Academic Article
• Detection of subtle left ventricular systolic dysfunction in patients with significant aortic regurgitation and preserved left ventricular ejection fraction: speckle tracking echocardiographic analysis  Academic Article
• Development and validation of a novel risk score for asthma exacerbations: The risk score for exacerbations  Academic Article
• Development of Renal Disease in People at High Cardiovascular Risk  Academic Article
• Development of System Performance Indicators for Adolescent and Young Adult Cancer Care and Control in Canada  Academic Article
• Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD  Academic Article
• Development of a depressed left ventricular ejection fraction in patients with left ventricular hypertrophy and a normal ejection fraction  Academic Article
• Development of end stage renal disease following an acute cardiac event  Academic Article
• Development of social functioning and communication in school-aged (5–9years) children with cerebral palsy  Academic Article
• Development of the Galaxy Chronic Obstructive Pulmonary Disease (COPD) Model Using Data from ECLIPSE: Internal Validation of a Linked-Equations Cohort Model  Academic Article
• Diabetic Myopathy: current molecular understanding of this novel neuromuscular disorder  Academic Article
• Diet and Kidney Disease in High-Risk Individuals With Type 2 Diabetes Mellitus  Academic Article
• Dietary interventions for multiple sclerosis-related outcomes  Academic Article
• Dietary risk factors for incidence or progression of chronic kidney disease in individuals with type 2 diabetes in the European Union  Academic Article
• Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease  Academic Article
• Differential expression of sputum and serum autoantibodies in patients with chronic obstructive pulmonary disease  Academic Article
• Digitalis for treatment of heart failure in patients in sinus rhythm  Academic Article
• Disability in Systemic Sclerosis — A Longitudinal Observational Study  Academic Article
• Disability progression in aggressive multiple sclerosis  Academic Article
• Discussing the potential for progression with patients newly diagnosed with multiple sclerosis: When, how, and why?  Academic Article
• Disease Course of Lower Respiratory Tract Infection With a Bacterial Cause  Academic Article
• Disease course patterns in systemic lupus erythematosus  Academic Article
• Disease-modifying therapies should be stopped in NMOSD patients in remission – Yes  Academic Article
• Do Major Cardiovascular Outcomes in Patients With Stable Ischemic Heart Disease in the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation Trial Differ by Healthcare System?  Academic Article
• Do We Know the Minimal Clinically Important Difference (MCID) for COPD Exacerbations?  Academic Article
• Does Femoroacetabular Impingement Contribute to the Development of Hip Osteoarthritis? A Systematic Review  Academic Article
• Dry Eye Disease in University-based Clinics in Canada: A Retrospective Chart Review  Academic Article
• Dual LABA/LAMA Therapy versus LABA or LAMA Monotherapy for Chronic Obstructive Pulmonary Disease. A Systematic Review and Meta-analysis in Support of the American Thoracic Society Clinical Practice Guideline  Academic Article
• EAACI position statement on asthma exacerbations and severe asthma  Academic Article
• Early dietary protein restriction slows disease progression and lengthens survival in mice with polycystic kidney disease.  Academic Article
• Economic Evaluation of Bevacizumab for the First-Line Treatment of Newly Diagnosed Glioblastoma Multiforme  Academic Article
• Editorial Perspective: Longitudinal research in autism - introducing the concept of ‘chronogeneity’  Academic Article
• Editorial: Extracellular Matrix: The Common Thread of Disease Progression in Fibrosis?  Academic Article
• Effect of Candesartan on Cause-Specific Mortality in Heart Failure Patients  Academic Article
• Effect of Coaching to Increase Water Intake on Kidney Function Decline in Adults With Chronic Kidney Disease  Academic Article
• Effect of Everolimus on Bone Marker Levels and Progressive Disease in Bone in BOLERO-2  Academic Article
• Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients  Academic Article
• Effect of Lipid Lowering With Rosuvastatin on Progression of Aortic Stenosis  Academic Article
• Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β₂-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE²SPOND). A Randomized Clinical Trial  Academic Article
• Effect of Rosiglitazone on Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease  Academic Article
• Effect of Telmisartan on Renal Outcomes  Academic Article
• Effect of Visit-to-Visit Blood Pressure Variability on Cognitive and Functional Decline in Mild to Moderate Alzheimer’s Disease  Academic Article
• Effect of continued antifibrotic therapy after forced vital capacity decline in patients with idiopathic pulmonary fibrosis; a real world multicenter cohort study  Academic Article
• Effect of delayed diagnosis on disease course and management of Churg–Strauss syndrome: a retrospective study  Academic Article
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• Hypothalamic-Pituitary-Adrenal Axis Dysfunction and Illness Progression in Bipolar Disorder  Academic Article
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