Disease Progression Concept

subject area of

• 2016 Addendum to the Canadian Guidelines for the Management of Plaque Psoriasis 2009  Journal Articles
• 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases  Journal Articles
• 45-Years Between Skin Lesions and CNS Symptoms in a Patient with Scleroderma  Journal Articles
• AMPK β1 reduces tumor progression and improves survival in p53 null mice  Journal Articles
• HIV virological rebounds but not blips predict liver fibrosis progression in antiretroviral‐treated HIV/hepatitis C virus‐coinfected patients  Journal Articles
• A 12-month follow-up study of discharged patients with acute pancreatitis: An acute condition with prolonged sequela.  Journal Articles
• A Clinical Prediction Model to Stratify Retinopathy of Prematurity Risk Using Postnatal Weight Gain  Journal Articles
• A Clinical Study of Migraine Evolution  Journal Articles
• A Comparison of the Health Utilities Indices Mark 2 and Mark 3 in Type 2 Diabetes  Journal Articles
• A Longitudinal, Population-Based, Cohort Study of Childhood Asthma Followed to Adulthood  Journal Articles
• A Multicenter Open-Label Study to Assess the Safety of a New Formulation of BLP25 Liposome Vaccine in Patients With Unresectable Stage III Non–Small-Cell Lung Cancer  Journal Articles
• A Multidimensional Approach to the Management of Severe Asthma: Inflammometry, Molecular Microbiology and Bronchial Thermoplasty  Journal Articles
• A Nurse-coordinated Model of Care versus Usual Care for Stage 3/4 Chronic Kidney Disease in the Community  Journal Articles
• A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration-resistant Prostate Cancer: Canadian Cancer Trials Group Study IND205  Journal Articles
• A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer  Journal Articles
• A Phase II Trial with Pharmacodynamic Endpoints of the Proteasome Inhibitor Bortezomib in Patients with Metastatic Colorectal Cancer  Journal Articles
• A Phase II study of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) and gemcitabine in advanced pancreatic carcinoma. A trial of the Princess Margaret Hospital Phase II consortium  Journal Articles
• A Practical Guide for Treatment of Rapidly Progressive ADPKD with Tolvaptan  Journal Articles
• A Protocol for a Pan-Canadian Prospective Observational Study on Active Surveillance or Surgery for Very Low Risk Papillary Thyroid Cancer  Journal Articles
• A Randomized Controlled Trial of Caries Prevention in Dental Practice  Journal Articles
• A Review of Physical Activity and Circulating miRNA Expression: Implications in Cancer Risk and Progression  Journal Articles
• A cluster-based analysis evaluating the impact of comorbidities in fibrotic interstitial lung disease  Journal Articles
• A community randomized controlled clinical trial of mixed carotenoids and micronutrient supplementation of patients with acquired immunodeficiency syndrome  Journal Articles
• A double-blind, randomized controlled trial to compare the effect of biannual peripheral magnetic resonance imaging, radiography and standard of care disease progression monitoring on pharmacotherapeutic escalation in rheumatoid and undifferentiated inflammatory arthritis: study protocol for a randomized controlled trial  Journal Articles
• A longitudinal study of the pathophysiological changes in single human thenar motor units in amyotrophic lateral sclerosis  Journal Articles
• A meta-analysis and systematic review of thalidomide for patients with previously untreated multiple myeloma  Journal Articles
• A multicentric phase II clinical trial on intra-arterial hepatic radiotherapy with 90yttrium SIR-spheres in unresectable, colorectal liver metastases refractory to i.v. chemotherapy: preliminary results on toxicity and response rates.  Journal Articles
• A new era in idiopathic pulmonary fibrosis: considerations for future clinical trials  Journal Articles
• A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease  Journal Articles
• A novel homozygous GALC mutation: Very early onset and rapidly progressive Krabbe disease  Journal Articles
• A novel take on idiopathic pulmonary fibrosis disease progression: localised autoimmunity  Journal Articles
• A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: a study of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG IND.168)  Journal Articles
• A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas  Conferences
• A phase II study of PS-341 (Bortezomib) in advanced or metastatic urothelial cancer. A trial of the Princess Margaret Hospital and University of Chicago phase II consortia  Journal Articles
• A phase II study of SB939, a novel pan-histone deacetylase inhibitor, in patients with translocation-associated recurrent/metastatic sarcomas—NCIC-CTG IND 200  Journal Articles
• A phase II study of cediranib (AZD 2171) in treatment naive patients with progressive unresectable recurrent or metastatic renal cell carcinoma. A trial of the PMH phase 2 consortium  Journal Articles
• A phase II study of doxorubicin/paclitaxel plus G-CSF for metastatic breast cancer.  Journal Articles
• A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial  Journal Articles
• A phase II study of obatoclax mesylate, a Bcl-2 antagonist, plus topotecan in relapsed small cell lung cancer  Journal Articles
• A phase II study of perifosine (D-21226) in patients with previously untreated metastatic or locally advanced soft tissue sarcoma: A National Cancer Institute of Canada Clinical Trials Group trial  Journal Articles
• A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer  Journal Articles
• A phase II study of sunitinib in patients with recurrent epithelial ovarian and primary peritoneal carcinoma: an NCIC Clinical Trials Group Study  Journal Articles
• A phase II trial of dovitinib in previously-treated advanced pleural mesothelioma: The Ontario Clinical Oncology Group  Journal Articles
• A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis  Journal Articles
• A pragmatic single-blind randomised controlled trial and economic evaluation of the use of leukotriene receptor antagonists in primary care at steps 2 and 3 of the national asthma guidelines (ELEVATE study).  Journal Articles
• A radiation-induced adaptive response prolongs the survival of prion-infected mice  Journal Articles
• A randomized placebo-controlled study of tamoxifen after adjuvant chemotherapy in premenopausal women with early breast cancer (National Cancer Institute of Canada—Clinical Trials Group Trial, MA.12)  Journal Articles
• A realist review to understand the efficacy and outcomes of interventions designed to minimise, reverse or prevent the progression of frailty  Journal Articles
• A role for sensory nerves in the late asthmatic response  Journal Articles
• A role for the TGFβ-Par6 polarity pathway in breast cancer progression  Journal Articles
• A stochastic approach to risk management for prostate cancer patients on active surveillance  Journal Articles
• A stochastic model for survival of early prostate cancer with adjustments for leadtime, length bias, and over‐detection  Journal Articles
• A systematic review on how patients value chronic obstructive pulmonary disease outcomes  Journal Articles
• A viscerally driven cachexia syndrome in patients with advanced colorectal cancer: contributions of organ and tumor mass to whole-body energy demands  Journal Articles
• ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer  Journal Articles
• AGA Technical Review on Gastric Intestinal Metaplasia—Natural History and Clinical Outcomes  Journal Articles
• APOL1 Genotype and Renal Function of Black Living Donors  Journal Articles
• ARDS in patients with thermal injury  Journal Articles
• Abiraterone acetate for patients with metastatic castration-resistant prostate cancer progressing after chemotherapy: final analysis of a multicentre, open-label, early-access protocol trial  Journal Articles
• Absence of renal sequelae after childhood Escherichia coli O157:H7 gastroenteritis  Journal Articles
• Accumulated Delivered Dose Response of Stereotactic Body Radiation Therapy for Liver Metastases  Journal Articles
• Activin mRNA induced during amygdala kindling shows a spatiotemporal progression that tracks the spread of seizures  Journal Articles
• Acute Precipitants of Congestive Heart Failure Exacerbations  Journal Articles
• Acute change in glomerular filtration rate with inhibition of the renin-angiotensin system does not predict subsequent renal and cardiovascular outcomes  Journal Articles
• Acute exacerbation of idiopathic pulmonary fibrosis: international survey and call for harmonisation  Journal Articles
• Acute exacerbations of progressive-fibrosing interstitial lung diseases  Journal Articles
• Adding ultrasound to treat-to-target shows no benefit in achieving clinical remission nor in slowing radiographic progression in rheumatoid arthritis: results from a multicenter prospective cohort  Journal Articles
• Advanced Chronic Kidney Disease in Lupus Nephritis: Is Dialysis Inevitable?  Journal Articles
• Akt isoform specific effects in ovarian cancer progression  Journal Articles
• Aldehyde dehydrogenase 3A1 associates with prostate tumorigenesis  Journal Articles
• All-cause hospitalizations in systemic lupus erythematosus from a large Canadian referral centre  Journal Articles
• Altered neuroendocrine status at the onset of CNS lupus-like disease  Journal Articles
• Amplification of MUC1 in prostate cancer metastasis and CRPC development  Journal Articles
• Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer  Journal Articles
• An Optimized Clinical Regimen for the Oncolytic Virus PV701  Journal Articles
• An Updated Systematic Review and Commentary Examining the Effectiveness of Radioactive Iodine Remnant Ablation in Well-Differentiated Thyroid Cancer  Journal Articles
• An atypical presentation of giant cell arteritis  Journal Articles
• Analysis of the Contribution of Salmonella Pathogenicity Islands 1 and 2 to Enteric Disease Progression Using a Novel Bovine Ileal Loop Model and a Murine Model of Infectious Enterocolitis  Journal Articles
• Androgen therapy in inherited bone marrow failure syndromes: analysis from the Canadian Inherited Marrow Failure Registry  Journal Articles
• Angiographic Disease Progression and Residual Risk of Cardiovascular Events While on Optimal Medical Therapy  Journal Articles
• Angiotensin Blockade Does Not Affect Fibrosis Progression in Recurrent Hepatitis C After Liver Transplantation  Journal Articles
• Animal models of COPD: What do they tell us?  Journal Articles
• Animal models of pulmonary fibrosis: how far from effective reality?  Journal Articles
• Antacid Therapy and Disease Progression in Patients with Idiopathic Pulmonary Fibrosis Who Received Pirfenidone  Journal Articles
• Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis  Journal Articles
• Antacid therapy in idiopathic pulmonary fibrosis: more questions than answers?  Journal Articles
• Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for people with asthma  Journal Articles
• Antiretroviral effects on HIV‐1 RNA, CD4 cell count and progression to AIDS or death: a meta‐regression analysis  Journal Articles
• Antiretroviral resistance testing in HIV-positive people  Journal Articles
• Anxiety in youth at clinical high risk for psychosis: A case study and conceptual model  Journal Articles
• ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis  Journal Articles
• Application of new acute kidney injury biomarkers in human randomized controlled trials  Journal Articles
• Applying contemporary antithrombotic therapy in the secondary prevention of chronic atherosclerotic cardiovascular disease  Journal Articles
• Approach to the detection and management of chronic kidney disease: What primary care providers need to know.  Journal Articles
• Areas of controversy in neuroprogression in bipolar disorder  Journal Articles
• Assessing sensitivity to change: choosing the appropriate change coefficient  Journal Articles
• Assessing the Educational Needs of Canadian Gastroenterologists and Gastroenterology Nurses: Challenges to Optimal Care in Crohn’s Disease  Journal Articles
• Assessing the Measurement Properties of the Self-Administered Amyotrophic Lateral Sclerosis Functional Rating Scale–Revised (ALSFRS-R): A Rasch Analysis  Journal Articles
• Assessing the Reliability of a Semiautomated Segmentation Algorithm for Quantifying Erosions in the Metacarpophalangeal Joints of Patients with Rheumatoid Arthritis  Journal Articles
• Assessment of biochemical recurrence of prostate cancer (Review)  Journal Articles
• Assessment on the Prevention of Progression by Rosiglitazone on Atherosclerosis in diabetes patients with Cardiovascular History (APPROACH): Study design and baseline characteristics  Journal Articles
• Association Between RECIST Changes and Survival in Patients with Metastatic Castration-resistant Prostate Cancer Receiving Docetaxel  Journal Articles
• Association between older age and adverse outcomes on antiretroviral therapy  Journal Articles
• Association between progression-free survival and health-related quality of life in oncology: a systematic review protocol  Journal Articles
• Association of Clonal Hematopoiesis of Indeterminate Potential with Worse Kidney Function and Anemia in Two Cohorts of Patients with Advanced Chronic Kidney Disease  Journal Articles
• Association of Delirium With Cognitive Decline in Late Life  Journal Articles
• Association of Gastroesophageal Factors and Worsening of Forced Vital Capacity in Systemic Sclerosis  Journal Articles
• Association of Intermittent and Constant Knee Pain Patterns With Knee Pain Severity and With Radiographic Knee Osteoarthritis Duration and Severity  Journal Articles
• Association of Low-Dose Colchicine With Incidence of Knee and Hip Replacements  Journal Articles
• Association of Multiple Cellular Stress Pathways With Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-Deficient Mice  Journal Articles
• Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals  Journal Articles
• Association of Patient Age With Progression of Low-risk Papillary Thyroid Carcinoma Under Active Surveillance  Journal Articles
• Association of Proteinuria and Incident Atrial Fibrillation in Patients With Intact and Reduced Kidney Function  Journal Articles
• Association of dose escalation of octreotide long‐acting release on clinical symptoms and tumor markers and response among patients with neuroendocrine tumors  Journal Articles
• Association of interleukin-10 levels with age of onset and duration of illness in patients with major depressive disorder  Journal Articles
• Association of renin–angiotensin and endothelial nitric oxide synthase gene polymorphisms with blood pressure progression and incident hypertension: prospective cohort study  Journal Articles
• Associations Between Childhood Cognition and Cardiovascular Events in Adulthood: A Systematic Review and Meta-analysis  Journal Articles
• Asthma Worsenings: Approaches to Prevention and Management from the Asthma Worsenings Working Group  Journal Articles
• Asthma progression and mortality: the role of inhaled corticosteroids  Journal Articles
• Atopic March: Collegium Internationale Allergologicum Update 2020  Journal Articles
• Atypical Polycystic Kidney Disease as defined by Imaging  Journal Articles
• Atypical clinical course in juvenile metachromatic leukodystrophy involving novel arylsulfatase A gene mutations  Journal Articles
• Autoantibodies and immune complexes to oxidation-specific epitopes and progression of aortic stenosis: Results from the ASTRONOMER trial  Journal Articles
• Autobiographical Memory and Patterns of Brain Atrophy in Fronto-temporal Lobar Degeneration  Journal Articles
• Autoimmune heparin‐induced thrombocytopenia and venous limb gangrene after aortic dissection repair: in vitro and in vivo effects of intravenous immunoglobulin  Journal Articles
• B Vitamins and Magnetic Resonance Imaging–Detected Ischemic Brain Lesions in Patients With Recent Transient Ischemic Attack or Stroke  Journal Articles
• Bacteria Challenge in Smoke-exposed Mice Exacerbates Inflammation and Skews the Inflammatory Profile  Journal Articles
• Balance Measures Over 12 Months in Individuals With Chronic Obstructive Pulmonary Disease  Journal Articles
• Barrett's Oesophagus Surveillance versus endoscopy at need Study (BOSS): protocol and analysis plan for a multicentre randomized controlled trial  Journal Articles
• Being careful: A grounded theory of emergent chronic knee problems  Journal Articles
• Beneficial effect of ginseng root in SOD-1 (G93A) transgenic mice  Journal Articles
• Benralizumab for Prednisone-Dependent Eosinophilic Asthma Associated With Novel STAT3 Loss of Function Mutation  Journal Articles
• Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial  Journal Articles
• Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways  Journal Articles
• Beyond the year 2000 in CHD research: current understanding of the cellular mechanism of atherosclerosis.  Journal Articles
• Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2  Journal Articles
• Biomarkers Predict Progression of Acute Kidney Injury after Cardiac Surgery  Journal Articles
• Biomarkers of inflammation and repair in kidney disease progression  Journal Articles
• Biomarkers of neuroprogression and late staging in bipolar disorder: A systematic review  Journal Articles
• Biotinidase is a Novel Marker for Papillary Thyroid Cancer Aggressiveness  Journal Articles
• Blood eosinophil count, a marker of inhaled corticosteroid effectiveness in preventing COPD exacerbations in post-hoc RCT and observational studies: systematic review and meta-analysis  Journal Articles
• Body mass index and chronic kidney disease outcomes after acute kidney injury: a prospective matched cohort study  Journal Articles
• Bone markers and their prognostic value in metastatic bone disease: Clinical evidence and future directions  Journal Articles
• Brain‐derived neurotrophic factor, impaired glucose metabolism, and bipolar disorder course  Journal Articles
• Burden of carotid artery atherosclerosis in Chinese adults: Implications for future risk of cardiovascular diseases  Journal Articles
• COPD exacerbations in the emergency department: Epidemiology and related costs. A retrospective cohort multicentre study from the Italian Society of Emergency Medicine (SIMEU)  Journal Articles
• COPD profiles and treatable traits using minimal resources: identification, decision tree and stability over time  Journal Articles
• CT Angiography “Spot Sign” Predicts Hematoma Expansion in Acute Intracerebral Hemorrhage  Journal Articles
• Cabozantinib for Progressive Metastatic Castration-resistant Prostate Cancer Following Docetaxel: Combined Analysis of Two Phase 3 Trials  Journal Articles
• Can Vitamin D Supplementation Improve the Severity of Congestive Heart Failure?  Journal Articles
• Can We Predict Exacerbations of Asthma?  Journal Articles
• Canadian Consensus: Oligoprogressive, Pseudoprogressive, and Oligometastatic Non-Small-Cell Lung Cancer  Journal Articles
• Canadian Helicobacter Study Group Consensus Conference: Update on the Management ofHelicobacter pylori- An Evidence-Based Evaluation of Six Topics Relevant to Clinical Outcomes in Patients Evaluated forH pyloriInfection  Journal Articles
• Canadian Ophthalmological Society evidence-based clinical practice guidelines for the periodic eye examination in adults in Canada.  Journal Articles
• Canadian expert consensus: optimal treatment of neovascular age-related macular degeneration  Journal Articles
• Cancer-Induced Oxidative Stress and Pain  Journal Articles
• Cardiovascular Safety Of Nintedanib In Subgroups By Cardiovascular Risk At Baseline In The Tomorrow And Inpulsis Trials  Conferences
• Case 216: Hypertrophic Spinal Pachymeningitis  Journal Articles
• Cerebral Microbleeds and the Effect of Intensive Blood Pressure Reduction on Hematoma Expansion and Functional Outcomes  Journal Articles
• Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function  Journal Articles
• Challenges and developments in research of the early stages of bipolar disorder  Journal Articles
• Change in bone mineral density as a function of age in women and men and association with the use of antiresorptive agents  Journal Articles
• Changes in skin score in early diffuse cutaneous systemic sclerosis are associated with changes in global disease severity  Journal Articles
• Changes in the aortic endothelium and plasma von Willebrand factor levels during the onset and progression of insulin-dependent diabetes in BB rats  Journal Articles
• Changing the bipolar illness trajectory  Journal Articles
• Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study  Journal Articles
• Characterization of human embryonic stem cells with features of neoplastic progression  Journal Articles
• Chiari malformation and tuberculous meningitis: aetiology and management  Journal Articles
• Childhood primary angiitis of the central nervous system: Identifying disease trajectories and early risk factors for persistently higher disease activity  Journal Articles
• Chronic obstructive pulmonary disease exacerbation purulence status and its association with pulmonary embolism: protocol for a systematic review with meta-analysis  Journal Articles
• Circulating Angiopoietin-2 as a Biomarker in ANCA-Associated Vasculitis  Journal Articles
• Circulating Levels of Matrix Gla Protein and Progression of Aortic Stenosis: A Substudy of the Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) Trial  Journal Articles
• Classifying kidney problems: can we avoid framing risks as diseases?  Journal Articles
• Clinical Decision-Making Tool for Safe and Effective Prescription of Exercise in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Results From an Interdisciplinary Delphi Survey and Focus Groups  Journal Articles
• Clinical Impact of Residual Extraretroperitoneal Masses in Patients With Advanced Nonseminomatous Germ Cell Testicular Cancer  Journal Articles
• Clinical Insights into Pulmonary Exacerbations in Cystic Fibrosis from the Microbiome. What Are We Missing?  Journal Articles
• Clinical Manifestations Associated With the N-Terminal-Acetyltransferase NAA10 Gene Mutation in a Girl: Ogden Syndrome  Journal Articles
• Clinical Staging in Bipolar Disorder  Journal Articles
• Clinical Trial Considerations in Developing Treatments for Early Stages of Common, Chronic Kidney Diseases: A Scientific Workshop Cosponsored by the National Kidney Foundation and the US Food and Drug Administration  Conferences
• Clinical Utility of Biochemical Markers of Bone Metabolism for Improving the Management of Patients with Advanced Multiple Myeloma  Journal Articles
• Clinical and biological implications of driver mutations in myelodysplastic syndromes  Journal Articles
• Clinical and pathological findings of SARS-CoV-2 infection and concurrent IgA nephropathy: a case report  Journal Articles
• Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer  Journal Articles
• Clinical course and treatment of incidentally detected splanchnic vein thrombosis: an individual patient data meta-analysis  Journal Articles
• Clinical implications and characterization of Group A Streptoccoccus infections in adults with cystic fibrosis  Journal Articles
• Clinical implications of a staging model for bipolar disorders  Journal Articles
• Clinical outcome following post‐chemotherapy retroperitoneal lymph node dissection in men with intermediate‐ and poor‐risk nonseminomatous germ cell tumour  Journal Articles
• Clinical outcomes in patients with systolic heart failure. Are atrial high rate episodes a common marker of disease progression?  Journal Articles
• Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value  Journal Articles
• Clonal Hematopoiesis of Indeterminate Potential and Kidney Function Decline in the General Population  Journal Articles
• Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas  Journal Articles
• Cocaine/crack use is not associated with fibrosis progression measured by AST-to-Platelet Ratio Index in HIV-HCV co-infected patients: a cohort study  Journal Articles
• Cohort Profile: The Canadian HIV-Hepatitis C Co-infection Cohort Study  Journal Articles
• Colchicine and aspirin in community patients with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial  Journal Articles
• Colchicine and the combination of rivaroxaban and aspirin in patients hospitalised with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial  Journal Articles
• Colds as predictors of the onset and severity of COPD exacerbations  Journal Articles
• Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer  Journal Articles
• Combining Gemcitabine and Capecitabine in Patients With Advanced Biliary Cancer: A Phase II Trial  Conferences
• Comparative diagnostic accuracy of knee adduction moments in knee osteoarthritis: A case for not normalizing to body size  Journal Articles
• Comparing the Health Utilities Index Mark 3 (HUI3) with the Short Form-36 Preference-Based SF-6D in Chronic Kidney Disease  Journal Articles
• Comparing virtual with conventional microscopy for the consensus diagnosis of Barrett’s neoplasia in the AspECT Barrett’s chemoprevention trial pathology audit  Journal Articles
• Comparison between conventional and "clinical" assessment of experimental lung fibrosis  Journal Articles
• Comparison of Echocardiographic and Cardiac Magnetic Resonance Imaging for Assessing Right Ventricular Function in Adults With Repaired Tetralogy of Fallot  Journal Articles
• Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism  Journal Articles
• Comparison of the effects of secondary prevention in schoolchildren between hospitals with and without mobile dental services in Southern Thailand  Journal Articles
• Comprehensive Care Management in Conjunction with Sputum Cytometry-Guided Pharmacotherapy in a Post-Discharge Clinic for Patients with COPD  Journal Articles
• Comprehensive Plasma Metabolomic Analyses of Atherosclerotic Progression Reveal Alterations in Glycerophospholipid and Sphingolipid Metabolism in Apolipoprotein E-deficient Mice  Journal Articles
• Concerning: “The sad plight of multiple sclerosis research (low on fact, high on fiction): critical data to support it being a neurocristopathy” by Peter O. Behan and Abhijit Chaudhuri  Journal Articles
• Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression.  Journal Articles
• Concurrent use of multiple low dose chemotherapy agents with differing mechanisms of action as a strategy vs passive resistance: A pilot study.  Journal Articles
• Consensus Statements for Management of Barrett's Dysplasia and Early-Stage Esophageal Adenocarcinoma, Based on a Delphi Process  Journal Articles
• Consensus on nomenclature for clinical staging models in bipolar disorder: A narrative review from the International Society for Bipolar Disorders (ISBD) Staging Task Force  Journal Articles
• Construct validity of the RAND-12 and Health Utilities Index Mark 2 and 3 in type 2 diabetes  Journal Articles
• Contactin-1 Reduces E-Cadherin Expression Via Activating AKT in Lung Cancer  Journal Articles
• Correlates of decline in gross motor capacity in adolescents with cerebral palsy in Gross Motor Function Classification System levels III to V: an exploratory study  Journal Articles
• Correlation of hypointensities in susceptibility-weighted images to tissue histology in dementia patients with cerebral amyloid angiopathy: a postmortem MRI study  Journal Articles
• Correlations between plasma homocysteine and folate concentrations and carotid atherosclerosis in high-risk individuals: baseline data from the Homocysteine and Atherosclerosis Reduction Trial (HART)  Journal Articles
• Cost effectiveness of highly active antiretroviral therapy in HIV-infected patients  Journal Articles
• Cost implications of the use of basal insulin glargine in people with early dysglycemia: The ORIGIN trial  Journal Articles
• Cost-Effectiveness Analysis of a Randomized Trial Comparing Care Models for Chronic Kidney Disease  Journal Articles
• Cost-Effectiveness of the Aerobika® Oscillating Positive Expiratory Pressure Device in the Management of Chronic Obstructive Pulmonary Disease Exacerbations in Canada  Journal Articles
• Critically Ill Patients With Severe Acute Respiratory Syndrome  Journal Articles
• Crosstalk between the Unfolded Protein Response and NF-κB-Mediated Inflammation in the Progression of Chronic Kidney Disease  Journal Articles
• Current management of advanced and castration resistant prostate cancer.  Journal Articles
• Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial  Journal Articles
• DO IT Trial: vitamin D Outcomes and Interventions in Toddlers –a TARGet Kids! randomized controlled trial  Journal Articles
• Decision Regret Following the Choice of Surgery or Active Surveillance for Small, Low-Risk Papillary Thyroid Cancer: A Prospective Cohort Study  Journal Articles
• Deep vein thrombosis: update on diagnosis and management  Journal Articles
• Defining Endoscopic Remission in Crohn’s Disease: MM-SES-CD and SES-CD Thresholds Associated With Low Risk of Disease Progression  Journal Articles
• Derivation and External Validation of Prediction Models for Advanced Chronic Kidney Disease Following Acute Kidney Injury  Journal Articles
• Design of the INPULSIS™ trials: Two phase 3 trials of nintedanib in patients with idiopathic pulmonary fibrosis  Journal Articles
• Detecting prodromal Alzheimer's disease in mild cognitive impairment: utility of the CAMCOG and other neuropsychological predictors  Journal Articles
• Detection and Early Referral of Patients With Interstitial Lung Abnormalities  Journal Articles
• Detection of COPD Exacerbations and Compliance With Patient-Reported Daily Symptom Diaries Using a Smartphone-Based Information System  Journal Articles
• Detection of subtle left ventricular systolic dysfunction in patients with significant aortic regurgitation and preserved left ventricular ejection fraction: speckle tracking echocardiographic analysis  Journal Articles
• Deterministic evolution and stringent selection during preneoplasia  Journal Articles
• Development and validation of a novel risk score for asthma exacerbations: The risk score for exacerbations  Journal Articles
• Development of Renal Disease in People at High Cardiovascular Risk  Journal Articles
• Development of System Performance Indicators for Adolescent and Young Adult Cancer Care and Control in Canada  Journal Articles
• Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD  Journal Articles
• Development of a depressed left ventricular ejection fraction in patients with left ventricular hypertrophy and a normal ejection fraction  Journal Articles
• Development of end stage renal disease following an acute cardiac event  Journal Articles
• Development of research capability in Ethiopia: the Ethio-Netherlands AIDS research project (ENARP): 1994-2002, achievements, scientific findings and project goals.  Journal Articles
• Development of social functioning and communication in school-aged (5–9years) children with cerebral palsy  Journal Articles
• Diabetic Myopathy: current molecular understanding of this novel neuromuscular disorder  Journal Articles
• Diet and Kidney Disease in High-Risk Individuals With Type 2 Diabetes Mellitus  Journal Articles
• Dietary interventions for multiple sclerosis-related outcomes  Journal Articles
• Dietary risk factors for incidence or progression of chronic kidney disease in individuals with type 2 diabetes in the European Union  Journal Articles
• Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease  Journal Articles
• Differential expression of sputum and serum autoantibodies in patients with chronic obstructive pulmonary disease  Journal Articles
• Digitalis for treatment of heart failure in patients in sinus rhythm  Journal Articles
• Disability in Systemic Sclerosis — A Longitudinal Observational Study  Journal Articles
• Disability progression in aggressive multiple sclerosis  Journal Articles
• Discussing the potential for progression with patients newly diagnosed with multiple sclerosis: When, how, and why?  Journal Articles
• Disease course patterns in systemic lupus erythematosus  Journal Articles
• Disease-modifying therapies should be stopped in NMOSD patients in remission – Yes  Journal Articles
• Do Major Cardiovascular Outcomes in Patients With Stable Ischemic Heart Disease in the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation Trial Differ by Healthcare System?  Journal Articles
• Do We Know the Minimal Clinically Important Difference (MCID) for COPD Exacerbations?  Journal Articles
• Does Femoroacetabular Impingement Contribute to the Development of Hip Osteoarthritis? A Systematic Review  Journal Articles
• Dry Eye Disease in University-based Clinics in Canada: A Retrospective Chart Review  Journal Articles
• EAACI position statement on asthma exacerbations and severe asthma  Journal Articles
• Early intervention, relapse prevention, and neuroprogression in bipolar disorder: The evidence matters  Journal Articles
• Early-immune development in asthma: A review of the literature  Journal Articles
• Economic Evaluation of Bevacizumab for the First-Line Treatment of Newly Diagnosed Glioblastoma Multiforme  Journal Articles
• Editorial Perspective: Longitudinal research in autism – introducing the concept of ‘chronogeneity’  Journal Articles
• Editorial: Extracellular Matrix: The Common Thread of Disease Progression in Fibrosis?  Journal Articles
• Effect of Candesartan on Cause-Specific Mortality in Heart Failure Patients  Journal Articles
• Effect of Coaching to Increase Water Intake on Kidney Function Decline in Adults With Chronic Kidney Disease  Journal Articles
• Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients  Journal Articles
• Effect of Lipid Lowering With Rosuvastatin on Progression of Aortic Stenosis  Journal Articles
• Effect of Nintedanib in Patients with Progressive Pulmonary Fibrosis in Subgroups with Differing Baseline Characteristics  Journal Articles
• Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β₂-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE²SPOND). A Randomized Clinical Trial  Journal Articles
• Effect of Rosiglitazone on Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease  Journal Articles
• Effect of Systemic Hypertension With Versus Without Left Ventricular Hypertrophy on the Progression of Atrial Fibrillation (from the Euro Heart Survey)  Journal Articles
• Effect of Telmisartan on Renal Outcomes  Journal Articles
• Effect of Visit-to-Visit Blood Pressure Variability on Cognitive and Functional Decline in Mild to Moderate Alzheimer’s Disease  Journal Articles
• Effect of continued antifibrotic therapy after forced vital capacity decline in patients with idiopathic pulmonary fibrosis; a real world multicenter cohort study  Journal Articles
• Effect of delayed diagnosis on disease course and management of Churg–Strauss syndrome: a retrospective study  Journal Articles
• Effect of nintedanib in patients with progressive pulmonary fibrosis associated with rheumatoid arthritis: data from the INBUILD trial  Journal Articles
• Effect of precautionary statements on the purchasing practices of Canadians directly and indirectly affected by food allergies  Journal Articles
• Effect of rosuvastatin on C-reactive protein and progression of aortic stenosis  Journal Articles
• Effect of statins on disease-related outcomes in patients with idiopathic pulmonary fibrosis  Journal Articles
• Effectiveness of Adding Everolimus to the First-line Treatment of Advanced Breast Cancer in Premenopausal Women Who Experienced Disease Progression While Receiving Selective Estrogen Receptor Modulators  Journal Articles
• Effectiveness of interventions to prevent pre-frailty and frailty progression in older adults: a systematic review  Journal Articles
• Effectiveness of the interventions in preventing the progression of pre-frailty and frailty in older adults: a systematic review protocol.  Journal Articles
• Effects of Medical Therapies on Retinopathy Progression in Type 2 Diabetes  Journal Articles
• Effects of Ramipril and Vitamin E on Atherosclerosis  Journal Articles
• Effects of Traditional Chinese Patent Medicine on Essential Hypertension  Journal Articles
• Effects of basal insulin glargine and omega‐3 on lower limb arterial disease outcome in patients with dysglycaemia: An analysis of the Outcome Reduction with an Initial Glargine INtervention (ORIGIN) trial  Journal Articles
• Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β₂-agonist fixed-dose combination: RE²SPOND rationale and study design  Journal Articles
• Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis  Journal Articles
• Efficacy and safety of a CXCR2 antagonist, AZD5069, in patients with uncontrolled persistent asthma: a randomised, double-blind, placebo-controlled trial  Journal Articles
• Efficacy and safety of nintedanib in patients with advanced idiopathic pulmonary fibrosis  Journal Articles
• Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial  Journal Articles
• Efficacy of Desloratadine in Persistent Allergic Rhinitis – A GA²LEN Study  Journal Articles
• Efficacy of Huoxiang Zhengqi dropping pills and Lianhua Qingwen granules in treatment of COVID-19: A randomized controlled trial  Journal Articles
• Efficacy of gene-therapy based on adenovirus encoding granulocyte-macrophage colony-stimulating factor in drug-sensitive and drug-resistant experimental pulmonary tuberculosis  Journal Articles
• Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trial  Journal Articles
• Elevated serum thiobarbituric acid reactive substances in clinically symptomatic schizophrenic males  Journal Articles
• Elevation of SIPL1 (SHARPIN) Increases Breast Cancer Risk  Journal Articles
• Eligibility criteria from pharmaceutical randomised controlled trials of idiopathic pulmonary fibrosis: a registry-based study  Journal Articles
• Emerging therapeutic targets for idiopathic pulmonary fibrosis: preclinical progress and therapeutic implications  Journal Articles
• Endoplasmic reticulum stress inhibition limits the progression of chronic kidney disease in the Dahl salt-sensitive rat  Journal Articles
• Endoscopic screening and surveillance for Barrett's esophagus--clinical implications.  Journal Articles
• Endoscopic screening and surveillance for Barrett's esophagus--clinical implications.  Journal Articles
• Eosinophilic, Solid, and Cystic Renal Cell Carcinoma  Journal Articles
• Epidemiological effects of seasonal oscillations in birth rates  Journal Articles
• Epidemiology and Prognostic Significance of Cough in Fibrotic Interstitial Lung Disease  Journal Articles
• Epidemiology of Chronic Pain with Psychological Comorbidity: Prevalence, Risk, Course, and Prognosis  Journal Articles
• Epidermal growth factor receptor-dependent activation of Gab1 is involved in ErbB-2-mediated mammary tumor progression  Journal Articles
• Establishing a Core Outcome Set for Autosomal Dominant Polycystic Kidney Disease: Report of the Standardized Outcomes in Nephrology–Polycystic Kidney Disease (SONG-PKD) Consensus Workshop  Journal Articles
• Establishment in Severe Combined Immunodeficiency Mice of Subrenal Capsule Xenografts and Transplantable Tumor Lines from a Variety of Primary Human Lung Cancers: Potential Models for Studying Tumor Progression–Related Changes  Journal Articles
• Estimates of the lifetime costs of breast cancer treatment in Canada  Journal Articles
• Estimating the cost of lung cancer diagnosis and treatment in Canada: the POHEM model.  Journal Articles
• Estimation of fibrosis progression rates for chronic hepatitis C: a systematic review and meta-analysis update  Journal Articles
• European Respiratory Society guidelines on long-term home non-invasive ventilation for management of COPD  Journal Articles
• Evaluating the effectiveness of rosuvastatin in preventing the progression of diastolic dysfunction in aortic stenosis: A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study  Journal Articles
• Evaluation of ¹⁸F-FDG PET and MRI Associations in Pediatric Diffuse Intrinsic Brain Stem Glioma: A Report from the Pediatric Brain Tumor Consortium  Journal Articles
• Evidence Informing the Intersection of HIV, Aging and Health: A Scoping Review  Journal Articles
• Evolution of Computed Tomography Angiography Spot Sign Is Consistent With a Site of Active Hemorrhage in Acute Intracerebral Hemorrhage  Journal Articles
• Exacerbation frequency and clinical outcomes in adult patients with cystic fibrosis  Journal Articles
• Exacerbations of Severe Asthma While on Anti–IL-5 Biologics  Journal Articles
• Exercise Reporting Template for Long COVID Patients: A Rehabilitation Practitioner Guide  Journal Articles
• Exercise prescription for hospitalized people with chronic obstructive pulmonary disease and comorbidities: a synthesis of systematic reviews  Journal Articles
• Expectant management versus immediate treatment for low‐grade cervical intraepithelial neoplasia  Journal Articles
• Exploring PI3Kδ Molecular Pathways in Stable COPD and Following an Acute Exacerbation, Two Randomized Controlled Trials  Journal Articles
• Exploring the Cystic Fibrosis Lung Microbiome: Making the Most of a Sticky Situation  Journal Articles
• Extracellular Heat Shock Proteins as Therapeutic Targets and Biomarkers in Fibrosing Interstitial Lung Diseases  Journal Articles
• Extracellular matrix microenvironment contributes actively to pulmonary fibrosis  Journal Articles
• Factors Associated With Rapid Progression to Endstage Kidney Disease in Lupus Nephritis  Journal Articles
• Factors associated with response to treatment of pulmonary exacerbations in cystic fibrosis patients  Journal Articles
• Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study  Journal Articles
• Fibrotic extracellular matrix induces release of extracellular vesicles with pro-fibrotic miRNA from fibrocytes  Journal Articles
• First Data on Efficacy and Safety of Nintedanib in Patients with Idiopathic Pulmonary Fibrosis and Forced Vital Capacity of ≤50 % of Predicted Value  Journal Articles
• First-Episode Psychosis: A Comparative Review of Diagnostic Evolution and Predictive Variables in Adolescents versus Adults  Journal Articles
• Five new pedigrees with inherited RUNX1 mutations causing familial platelet disorder with propensity to myeloid malignancy  Journal Articles
• Five-Day Telithromycin Once Daily Is as Effective as 10-Day Clarithromycin Twice Daily for the Treatment of Acute Exacerbations of Chronic Bronchitis and Is Associated With Reduced Health-Care Resource Utilization  Journal Articles
• Flavopiridol in Untreated or Relapsed Mantle-Cell Lymphoma: Results of a Phase II Study of the National Cancer Institute of Canada Clinical Trials Group  Journal Articles
• Focal therapy for oligometastatic and oligoprogressive renal cell carcinoma: a narrative review.  Journal Articles
• For Which Glaucoma Suspects Is It Appropriate to Initiate Treatment?  Journal Articles
• From neuroprogression to neuroprotection: implications for clinical care.  Journal Articles
• GFI1 is required for RUNX1/ETO positive acute myeloid leukemia  Journal Articles
• Gemcitabine Plus Carboplatin Compared With Carboplatin in Patients With Platinum-Sensitive Recurrent Ovarian Cancer: An Intergroup Trial of the AGO-OVAR, the NCIC CTG, and the EORTC GCG  Journal Articles
• Gemcitabine concurrent with continuous infusional 5-fluorouracil in advanced biliary cancers: a review of the Princess Margaret Hospital experience  Journal Articles
• Gender Differences in Fears Related to Low-Risk Papillary Thyroid Cancer and Its Treatment  Journal Articles
• Gene Transfer of Matrix Metalloproteinase-9 Induces Tumor Regression of Breast CancerIn vivo  Journal Articles
• Genetic drivers of heterogeneity in type 2 diabetes pathophysiology  Journal Articles
• Genomic Classifier Performance in Intermediate-Risk Prostate Cancer: Results From NRG Oncology/RTOG 0126 Randomized Phase 3 Trial  Journal Articles
• Global trends in myopia management attitudes and strategies in clinical practice  Journal Articles
• Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021  Journal Articles
• Growth inhibition of prostate cancer xenografts by halofuginone*†  Journal Articles
• HDL Cholesterol, LDL Cholesterol, and Triglycerides as Risk Factors for CKD: A Mendelian Randomization Study  Journal Articles
• Hanshiyi Formula, a medicine for Sars-CoV2 infection in China, reduced the proportion of mild and moderate COVID-19 patients turning to severe status: A cohort study  Journal Articles
• Health care costs associated with hepatitis C virus infection in First Nations populations in Ontario: a retrospective matched cohort study  Journal Articles
• Health-Related Quality of Life in Men With Metastatic Prostate Cancer Treated With Prednisone Alone or Mitoxantrone and Prednisone  Journal Articles
• Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema  Journal Articles
• Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function  Journal Articles
• Hemosiderin in sputum macrophages may predict infective exacerbations of chronic obstructive pulmonary disease: a retrospective observational study  Journal Articles
• Heritable pathologic cardiac hypertrophy in adulthood is preceded by neonatal cardiac growth restriction  Journal Articles
• High Kellgren-Lawrence Grade and Bone Marrow Lesions Predict Worsening Rates of Radiographic Joint Space Narrowing; The SEKOIA Study  Journal Articles
• High Versus Ultra-high Purity Factor VIII Concentrate Therapy: Prospective Evaluation of Immunological and Clinical Parameters in HIV Seronegative and Seropositive Hemophiliacs  Journal Articles
• High salt diet exacerbates colitis in mice by decreasing Lactobacillus levels and butyrate production  Journal Articles
• High-intensity Focused Ultrasound (HIFU) as salvage therapy for radio-recurrent prostate cancer: predictors of disease response.  Conferences
• Higher Body Mass Index Is Associated with Iron Deficiency in Children 1 to 3 Years of Age  Journal Articles
• Hippocampal volume and verbal memory performance in late-stage bipolar disorder  Journal Articles
• Home Respiratory Strategies in Patients With COPD With Chronic Hypercapnic Respiratory Failure  Journal Articles
• How can we define low disease activity in systemic lupus erythematosus?  Journal Articles
• How much is too much? The treatment of mild asthma  Journal Articles
• How to define responders in osteoarthritis  Journal Articles
• Hsp72 preserves muscle function and slows progression of severe muscular dystrophy  Journal Articles
• Human Adipose Tissue Macrophages Display Activation of Cancer-related Pathways  Journal Articles
• Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients  Journal Articles
• Hydroxychloroquine-Induced Cardiomyopathy in Systemic Lupus Erythematosus  Journal Articles
• Hyperprogressive disease in early-phase immunotherapy trials: Clinical predictors and association with immune-related toxicities.  Journal Articles
• Hypertension as an Underlying Factor in Heart Failure With Preserved Ejection Fraction  Journal Articles
• Hypothalamic-Pituitary-Adrenal Axis Dysfunction and Illness Progression in Bipolar Disorder  Journal Articles
• Hypoxia factors suffocate leukemic stem cell initiation  Journal Articles
• IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis  Journal Articles
• IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke–induced Lymphoid Neogenesis  Journal Articles
• IMI – Clinical Myopia Control Trials and Instrumentation Report  Journal Articles
• IMI – Myopia Control Reports Overview and Introduction  Journal Articles
• INHIBITION OF WILMS TUMOR XENOGRAFT PROGRESSION BY HALOFUGINONE IS ACCOMPANIED BY ACTIVATION OF WT-1 GENE EXPRESSION  Conferences
• Identifying Trajectories of Borderline Personality Features in Adolescence  Journal Articles
• Idiopathic pulmonary fibrosis: state of the art for 2023  Journal Articles
• Illness duration and total brain gray matter in bipolar disorder: Evidence for neurodegeneration?  Journal Articles
• Immune Responses to the Mycobacterium tuberculosis -Specific Antigen ESAT-6 Signal Subclinical Infection among Contacts of Tuberculosis Patients  Journal Articles
• Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis  Journal Articles
• Impact of Acarbose on Incident Diabetes and Regression to Normoglycemia in People With Coronary Heart Disease and Impaired Glucose Tolerance: Insights From the ACE Trial  Journal Articles
• Impact of Habitual Exercise on the Strength of Individuals with Myotonic Dystrophy Type 1  Journal Articles
• Impact of baseline BMI and weight change in CCTG adjuvant breast cancer trials  Journal Articles
• Impact of hepatitis C viral replication on CD4+ T-lymphocyte progression in HIV–HCV coinfection before and after antiretroviral therapy  Journal Articles
• Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression  Journal Articles
• Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis  Journal Articles
• Implications of Microbiota and Immune System in Development and Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease  Journal Articles
• Improving the management of chronic kidney disease in primary care by enhancing laboratory reports with additional information and follow-up procedures.  Journal Articles
• In patients with severe sepsis, hydrocortisone did not prevent progression to septic shock  Journal Articles
• Incidence and Predictors of Atrial Fibrillation Progression  Journal Articles
• Incidence and predictors of atrial fibrillation progression: A systematic review and meta-analysis  Journal Articles
• Incident Atrial Fibrillation and the Risk of Congestive Heart Failure, Myocardial Infarction, End-Stage Kidney Disease, and Mortality Among Patients With a Decreased Estimated GFR  Journal Articles
• Increased rates of obesity in first-presentation adults with mood disorders over the course of four-year follow-up  Journal Articles
• Increased susceptibility of asymmetrically prominent cortical veins correlates with misery perfusion in patients with occlusion of the middle cerebral artery  Journal Articles
• Infiltration or sealing of noncavitated proximal carious lesions is probably effective in preventing their progression compared with noninvasive strategies  Journal Articles
• Inflammatory Cerebrospinal Fluid in Sporadic Creutzfeldt-Jakob Disease  Journal Articles
• Inflammatory Mechanisms Are a Minor Component of the Pathogenesis of Idiopathic Pulmonary Fibrosis  Journal Articles
• Influence of Nonfatal Hospitalization for Heart Failure on Subsequent Mortality in Patients With Chronic Heart Failure  Journal Articles
• Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood  Journal Articles
• Insulin Resistance and LVH Progression in Patients With Calcific Aortic Stenosis  Journal Articles
• Insulin-like growth factor-binding protein 7 and risk of congestive heart failure hospitalization in patients with atrial fibrillation  Conferences
• Integration of Bone and Computed Tomography Scans to Assess Bone Metastasis in Metastatic Castration-Resistant Prostate Cancer  Journal Articles
• Interactions of cumulative load with biomarkers of cartilage turnover predict knee cartilage change over 2 years: data from the osteoarthritis initiative  Journal Articles
• Interim PET-results for prognosis in adults with Hodgkin lymphoma: a systematic review and meta-analysis of prognostic factor studies  Journal Articles
• Interim PET-results for prognosis in adults with Hodgkin lymphoma: a systematic review and meta-analysis of prognostic factor studies  Journal Articles
• Intestinal epithelial barrier dysfunction and dendritic cell redistribution during early stages of inflammation in the rat: Role for TLR-2 and -4 blockage  Journal Articles
• Intra-articular hyaluronate in experimental rabbit osteoarthritis can prevent changes in cartilage proteoglycan content11Supported by the Department of Trade and Industry (UK), the Scottish Home and Health Department, the Wellcome Trust and the University of Edinburgh.  Journal Articles
• Intracerebral hemorrhage in a patient with SLE and catastrophic antiphospholipid syndrome (CAPS): report of a case  Journal Articles
• Intracerebral rhabdoid and papillary meningioma with leptomeningeal spread and rapid clinical progression.  Journal Articles
• Intraluminal Administration of Poly I:C Causes an Enteropathy That Is Exacerbated by Administration of Oral Dietary Antigen  Journal Articles
• Intraocular pressure control and visual field changes in primary angle closure disease: the CUHK PACG Longitudinal (CUPAL) study  Journal Articles
• Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis  Journal Articles
• Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma  Journal Articles
• Intravenous Immunoglobulin Does Not Improve Outcome in Toxic Epidermal Necrolysis  Journal Articles
• Introducing the COPD Foundation Guide for Diagnosis and Management of COPD, Recommendations of the COPD Foundation  Journal Articles
• Is SABR Cost-Effective in Oligometastatic Cancer? An Economic Analysis of the SABR-COMET Randomized Trial  Conferences
• Is bipolar disorder associated with premature aging?  Journal Articles
• Is ventilation heterogeneity related to asthma control?  Journal Articles
• Joint Modeling of Clinical and Biomarker Data in Acute Kidney Injury Defines Unique Subphenotypes with Differing Outcomes  Journal Articles
• Joint trajectories of depression and perfectionism across adolescence and childhood risk factors  Journal Articles
• Juvenile Dermatomyositis  Journal Articles
• Lack of Effect of Methylene Blue in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis  Journal Articles
• Lactoferrin Reduces Necrotizing Enterocolitis Severity by Upregulating Intestinal Epithelial Proliferation  Journal Articles
• Late effects care for childhood brain Tumor Survivors: A Quality-Improvement Initiative  Journal Articles
• Late effects care for childhood brain Tumor Survivors: A Quality-Improvement Initiative.  Journal Articles
• Left Atrial Dysfunction in the Pathogenesis of Cryptogenic Stroke: Novel Insights from Speckle-Tracking Echocardiography  Journal Articles
• Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development  Journal Articles
• Lifetime Pattern of Atrial Fibrillation and the Risks of Stroke and Death in a Population-based Cohort of Men (from The Manitoba Follow-Up Study)  Journal Articles
• Lifetime cocaine use is a potential predictor for conversion from major depressive disorder to bipolar disorder: A prospective study  Journal Articles
• Limitation to muscular activity in chronic obstructive pulmonary disease  Journal Articles
• Limited Protective Effect of the CCR5Δ32/CCR5Δ32 Genotype on Human Immunodeficiency Virus Infection Incidence in a Cohort of Patients with Hemophilia and Selection for Genotypic X4 Virus  Journal Articles
• Links Between Anxiety and Allergies: Psychobiological Reality or Possible Methodological Bias?  Journal Articles
• Lipid Lowering on Progression of Mild to Moderate Aortic Stenosis: Meta-analysis of the Randomized Placebo-Controlled Clinical Trials on 2344 Patients  Journal Articles
• Lipoprotein(a) and Calcific Aortic Valve Stenosis Progression  Journal Articles
• Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis  Journal Articles
• Long-term Survival After Heart Failure  Journal Articles
• Long-term deterioration of quality of life in adult patients with celiac disease is associated with treatment noncompliance  Journal Articles
• Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials  Journal Articles
• Longitudinal Association Between BMI at Diagnosis and HIV Disease Progression  Journal Articles
• Longitudinal Invariance of Measurement and Structure of Global Self-Concept: A Population-Based Study Examining Trajectories Among Adolescents With and Without Chronic Illness  Journal Articles
• Longitudinal analysis of disability outcomes among young people with MS  Journal Articles
• Longitudinal changes in intermuscular fat volume and quadriceps muscle volume in the thighs of women with knee osteoarthritis  Journal Articles
• Longitudinal examination of lipid profiles in pediatric systemic lupus erythematosus  Journal Articles
• Loss of SR-BI Expression Leads to the Early Onset of Occlusive Atherosclerotic Coronary Artery Disease, Spontaneous Myocardial Infarctions, Severe Cardiac Dysfunction, and Premature Death in Apolipoprotein E–Deficient Mice  Journal Articles
• Loss of adipose tissue and plasma phospholipids: Relationship to survival in advanced cancer patients  Journal Articles
• Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells  Journal Articles
• Low CD4 T Cell Counts before HIV‐1 Seroconversion Do Not Affect Disease Progression in Ethiopian Factory Workers  Journal Articles
• Low CD4+ T-cell count and high HIV viral load precede the development of tuberculosis disease in a cohort of HIV-positive Ethiopians.  Journal Articles
• Low CD4+ T-cell count and high HIV viral load precede the development of tuberculosis disease in a cohort of HIV-positive ethiopians.  Journal Articles
• Low absolute CD4 counts in Ethiopians.  Journal Articles
• Low-density Lipoprotein Receptor Activities, Lipids, Apolipoprotein, and Clinical Course of Patients with Steroid-resistant Nephrotic Syndrome Treated with Low-density Lipoprotein Apheresis: A Case Series  Journal Articles
• Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts  Journal Articles
• Lumbar Spine Bone Mineral Density at Diagnosis and During Follow-Up in Children With IBD  Journal Articles
• Lung Volume Reduction Surgery vs Medical Treatment^*  Journal Articles
• Lung function decline in asthma  Journal Articles
• Lung imaging patterns in connective tissue disease–associated interstitial lung disease impact prognosis and immunosuppression response  Journal Articles
• Lupus myocarditis: a single center experience and a comparative analysis of observational cohort studies  Journal Articles
• Ly6C^hiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis  Journal Articles
• MRI ventilation abnormalities predict quality-of-life and lung function changes in mild-to-moderate COPD: longitudinal TINCan study  Journal Articles
• Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension  Journal Articles
• Major surgery seems not to influence HIV disease progression in haemophilia patients  Journal Articles
• Making the case for causality: what role do lung microbiota play in idiopathic pulmonary fibrosis?  Journal Articles
• Management Strategies for a Better Outcome in Unstable Coronary Artery Disease  Journal Articles
• Management Strategies to Improve Outcomes of Patients With Inflammatory Bowel Diseases  Journal Articles
• Markers of Bone Metabolism and Survival in Men with Hormone-Refractory Metastatic Prostate Cancer  Journal Articles
• Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer.  Journal Articles
• Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis  Conferences
• Mediators of allostasis and systemic toxicity in bipolar disorder  Journal Articles
• Metabolic acidosis is associated with increased risk of adverse kidney outcomes and mortality in patients with non-dialysis dependent chronic kidney disease: an observational cohort study  Journal Articles
• Metabolomic profiling of asthma and chronic obstructive pulmonary disease: A pilot study differentiating diseases  Journal Articles
• Metformin in adults with type 1 diabetes: Design and methods of REducing with MetfOrmin Vascular Adverse Lesions (REMOVAL): An international multicentre trial  Journal Articles
• Microglial cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plaque degradation  Journal Articles
• Micronutrient Deficiency and Treatment Adherence in a Randomized Controlled Trial of Micronutrient Supplementation in ART-Naïve Persons with HIV  Journal Articles
• Mild Cognitive Impairment Status and Mobility Performance: An Analysis From the Boston RISE Study  Journal Articles
• Mild cognitive decline. A position statement of the Cognitive Decline Group of the European Innovation Partnership for Active and Healthy Ageing (EIPAHA)  Journal Articles
• Mineralocorticoid receptor antagonists in patients with chronic kidney disease  Journal Articles
• Modeling the Initiation and Progression of Human Acute Leukemia in Mice  Journal Articles
• Modeling the Population-Level Effects of Male Circumcision as an HIV-Preventive Measure: A Gendered Perspective  Journal Articles
• Modifiable Lifestyle Factors for Primary Prevention of CKD: A Systematic Review and Meta-Analysis  Journal Articles
• Modifiable lifestyle and social factors affect chronic kidney disease in high-risk individuals with type 2 diabetes mellitus  Journal Articles
• Molecular Mechanisms Linking Diabetes to the Accelerated Development of Atherosclerosis  Journal Articles
• Molecular and Histological Analysis of a New Rat Model of Experimental Knee Osteoarthritis  Conferences
• Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts  Journal Articles
• Monophasic Disease Course in Systemic Lupus Erythematosus  Journal Articles
• Mortality after admission with pneumonia is higher than after admission with an exacerbation of COPD  Journal Articles
• Multicenter, Randomized Phase II Trial of Oral CI-1033 for Previously Treated Advanced Ovarian Cancer  Journal Articles
• Multicentre validation of the bedside paediatric early warning system score: a severity of illness score to detect evolving critical illness in hospitalised children  Journal Articles
• Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure  Journal Articles
• Multiple CT Scans Extend Lifespan by Delaying Cancer Progression in Cancer-Prone Mice  Journal Articles
• Multiple-Breath Washout as a Lung Function Test in Cystic Fibrosis. A Cystic Fibrosis Foundation Workshop Report  Journal Articles
• Multistate Analysis of Interval-Censored Longitudinal Data: Application to a Cohort Study on Performance Status Among Patients Diagnosed With Cancer  Journal Articles
• Myeloid GSK3α Deficiency Reduces Lesional Inflammation and Neovascularization during Atherosclerotic Progression.  Journal Articles
• National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. Design of Clinical Trials Working Group Report  Journal Articles
• Natural Progression of Symptom Change and Recovery From Concussion in a Pediatric Population  Journal Articles
• Natural history of cervical squamous intraepithelial lesions: a meta-analysis*1  Journal Articles
• Ndel1 oligopeptidase activity as a potential biomarker of early stages of schizophrenia  Journal Articles
• Negative Regulation of β4 Integrin Transcription by Homeodomain-Interacting Protein Kinase 2 and p53 Impairs Tumor Progression  Journal Articles
• Neighborhood-Level Disadvantage Impacts on Patients with Fibrotic Interstitial Lung Disease  Journal Articles
• Nephrology comanagement and the quality of antibiotic prescribing in primary care for patients with chronic kidney disease: a retrospective cross-sectional study  Journal Articles
• Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer  Journal Articles
• Neurobiological correlates of illness progression in the recurrent affective disorders  Journal Articles
• Neurohumoral variability in left ventricular dysfunction  Journal Articles
• Neuroprogression and Cognitive Functioning in Bipolar Disorder: A Systematic Review  Journal Articles
• Neuroprogression and illness trajectories in bipolar disorder  Journal Articles
• Neuroprogression and staging in psychiatry: historical considerations  Journal Articles
• Neurotrophins, cytokines, oxidative parameters and funcionality in Progressive Muscular Dystrophies  Journal Articles
• New Features of Disease After Diagnosis in 6 Forms of Systemic Vasculitis  Journal Articles
• New treatment paradigms for ADPKD: moving towards precision medicine  Journal Articles
• Newly diagnosed type 2 diabetes may serve as a potential marker for pancreatic cancer  Journal Articles
• Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial  Journal Articles
• Nintedanib and immunomodulatory therapies in progressive fibrosing interstitial lung diseases  Journal Articles
• Nintedanib in Asian patients with progressive fibrosing interstitial lung diseases: Results from the INBUILD trial  Journal Articles
• Nintedanib in Progressive Fibrosing Interstitial Lung Diseases  Journal Articles
• Nintedanib in patients with progressive fibrosing interstitial lung diseases—subgroup analyses by interstitial lung disease diagnosis in the INBUILD trial: a randomised, double-blind, placebo-controlled, parallel-group trial  Journal Articles
• Nintedanib in progressive interstitial lung diseases: data from the whole INBUILD trial  Journal Articles
• No Association Linking Short-Term Proton Pump Inhibitor Use to Dementia: Systematic Review and Meta-analysis of Observational Studies  Journal Articles
• Novel Approach to Estimate Osteoarthritis Progression: Use of the Reliable Change Index in the Evaluation of Joint Space Loss  Journal Articles
• Novel Biomarkers for Change in Renal Function in People With Dysglycemia  Journal Articles
• Numerical study of the effect of head and eye movement on progression of retinal detachment  Journal Articles
• Obesity and renal cell carcinoma: epidemiology, underlying mechanisms and management considerations  Journal Articles
• Occupational exposures and exacerbations of asthma and COPD—A general population study  Journal Articles
• Once daily long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease  Journal Articles
• Opposing Functions of Akt Isoforms in Lung Tumor Initiation and Progression  Journal Articles
• Optimizing nonpharmacological management following an acute exacerbation of chronic obstructive pulmonary disease  Journal Articles
• Oral Chronic Graft-vs.-Host Disease Characterization Using the NIH Scale  Journal Articles
• Osteoarthritis, cerebrovascular dysfunction and the common denominator of inflammation: a narrative review  Journal Articles
• Osteoporotic fractures and obesity affect frailty progression: a longitudinal analysis of the Canadian multicentre osteoporosis study  Journal Articles
• Outcomes and Findings of the International Rheumatoid Arthritis (RA) BIODAM Cohort for Validation of Soluble Biomarkers in RA  Journal Articles
• Outcomes and Resource Utilization Among Patients Admitted to the Intensive Care Unit Following Acute Exacerbation of Chronic Obstructive Pulmonary Disease  Journal Articles
• Outcomes in Patients With Clinical Stage III NSGCT Who Achieve Complete Clinical Response to Chemotherapy at Extraretroperitoneal Disease Site  Journal Articles
• Outcomes of sustained low efficiency dialysis versus continuous renal replacement therapy in critically ill adults with acute kidney injury: a cohort study  Journal Articles
• Overexpression of MUC1 and Genomic Alterations in Its Network Associate with Prostate Cancer Progression  Journal Articles
• Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis  Journal Articles
• PILOTING A RENAL DRUG ALERT SYSTEM FOR PRESCRIBING TO RESIDENTS IN LONG‐TERM CARE  Journal Articles
• Paclitaxel and bevacizumab with or without capecitabine as first-line treatment for HER2-negative locally recurrent or metastatic breast cancer: A multicentre, open-label, randomised phase 2 trial  Journal Articles
• Palliative care in interstitial lung disease: living well  Journal Articles
• Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors  Journal Articles
• Patients With Coronary Artery Disease Unsuitable for Revascularization: Definition, General Principles, and a Classification  Journal Articles
• Patterns of Care During the Terminal Hospital Admission for Patients With Advanced Heart Failure: A Retrospective Cohort Study  Journal Articles
• Patterns of clinical presentation in Takayasu's arteritis  Journal Articles
• Patterns of disease progression and outcomes in a randomized trial testing ABVD alone for patients with limited-stage Hodgkin lymphoma  Journal Articles
• Patterns of joint involvement in juvenile idiopathic arthritis and prediction of disease course: A prospective study with multilayer non-negative matrix factorization  Journal Articles
• Pediatric modification of the Montreal classification for inflammatory bowel disease  Journal Articles
• Perspectives that Influence Action Plans for Chronic Obstructive Pulmonary Disease  Journal Articles
• Pharmacological treatment of dementia.  Journal Articles
• Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas  Journal Articles
• Phase II Stopping Rules That Employ Response Rates and Early Progression  Journal Articles
• Phase II Study of Temsirolimus in Women With Recurrent or Metastatic Endometrial Cancer: A Trial of the NCIC Clinical Trials Group  Journal Articles
• Phase II Study of the Efficacy and Tolerability of Two Dosing Regimens of the Farnesyl Transferase Inhibitor, R115777, in Advanced Breast Cancer  Journal Articles
• Phase II Trial of Sorafenib in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck or Nasopharyngeal Carcinoma  Conferences
• Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer  Journal Articles
• Phase II study of ispinesib in recurrent or metastatic squamous cell carcinoma of the head and neck  Conferences
• Phosphodiesterase 4B inhibition: a potential novel strategy for treating pulmonary fibrosis  Journal Articles
• Phosphoinositide‐3 kinase activity in severe eosinophilic asthma with recurrent airway infections and neutrophilic exacerbations  Journal Articles
• Physical Therapy Practice Patterns in Acute Exacerbations of Chronic Obstructive Pulmonary Disease  Journal Articles
• Plant-based diets to manage the risks and complications of chronic kidney disease  Journal Articles
• Plasma Exchange for Renal Vasculitis and Idiopathic Rapidly Progressive Glomerulonephritis: A Meta-analysis  Journal Articles
• Plasma cell proliferative index is an independent predictor of progression in smoldering multiple myeloma  Journal Articles
• Plasma exchange with albumin replacement and disease progression in amyotrophic lateral sclerosis: a pilot study  Journal Articles
• Plasma pro-surfactant protein B and lung function decline in smokers  Journal Articles
• Plasma tocopherols and risk of cognitive impairment in an elderly Italian cohort  Journal Articles
• Pleomorphic xanthoastrocytoma  Conferences
• Pluripotent human stem cell lines: what we can learn about cancer initiation  Journal Articles
• Polo-Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice  Journal Articles
• Population pharmacokinetics of subcutaneous C1‐inhibitor for prevention of attacks in patients with hereditary angioedema  Journal Articles
• Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA‐ARIA‐EPOS‐AIRWAYS ICP statement  Journal Articles
• Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial  Journal Articles
• Potential Masking Effects of Salmeterol on Airway Inflammation in Asthma  Journal Articles
• Potential importance of residual confounding in systematic reviews of observational studies: Answer to Mathur and Vanderweele  Journal Articles
• Potential of nintedanib in treatment of progressive fibrosing interstitial lung diseases  Journal Articles
• Pre-operative bevacizumab, capecitabine, oxaliplatin and radiation among patients with locally advanced or low rectal cancer: A phase II trial  Journal Articles
• Precursor form of brain‐derived neurotrophic factor and mature brain‐derived neurotrophic factor are decreased in the pre‐clinical stages of Alzheimer's disease  Journal Articles
• Predicting Intracerebral Hemorrhage Growth With the Spot Sign  Journal Articles
• Predicting Low Disease State and Remission in Early Rheumatoid Arthritis in the First Six Months, Comparing the Simplified Disease Activity Index and European League Against Rheumatism Response Measures: Results From an Early Arthritis Cohort  Journal Articles
• Predicting New-onset Exertional and Resting Hypoxemia in Fibrotic Interstitial Lung Disease  Journal Articles
• Predicting Risk of Chronic Kidney Disease in Infants and Young Children at Diagnosis of Posterior Urethral Valves: Initial Ultrasound Kidney Characteristics and Validation of Parenchymal Area as Forecasters of Renal Reserve  Journal Articles
• Predicting asthma outcomes  Journal Articles
• Predictive value of European Scleroderma Group Activity Index in an early scleroderma cohort  Journal Articles
• Predictors of aging out of heavy episodic drinking in emerging adults: a systematic review protocol  Journal Articles
• Predictors of progression to chronic dialysis in survivors of severe acute kidney injury: a competing risk study  Journal Articles
• Presentation and Disease Course of Childhood‐Onset Versus Adult‐Onset Takayasu Arteritis  Journal Articles
• Prevalence and Progression of Incidental Terminal Ileitis on Non-diagnostic Colonoscopy: A Systematic Review and Meta-analysis  Journal Articles
• Prevalence and characteristics of progressive fibrosing interstitial lung disease in a prospective registry  Journal Articles
• Prevalence and outcomes of heart failure phenotypes in patients with atrial fibrillation  Journal Articles
• Prevalence and progression of internal carotid artery stenosis in patients with peripheral arterial occlusive disease  Journal Articles
• Prevalence, Persistence, and Sociodemographic Correlates of DSM-IV Disorders in the National Comorbidity Survey Replication Adolescent Supplement  Journal Articles
• Preventing Alzheimer's disease and cognitive decline.  Journal Articles
• Preventing disability from work-related low-back pain. New evidence gives new hope--if we can just get all the players onside.  Journal Articles
• Prevention of Chronic Kidney Disease and Subsequent Effect on Mortality: A Systematic Review and Meta-Analysis  Journal Articles
• Prognosis, disease progression, and treatment of atrial fibrillation patients during 1 year: follow-up of the Euro Heart Survey on Atrial Fibrillation  Journal Articles
• Prognostic Impact of the Neutrophil-to-Lymphocyte Ratio in Men With Metastatic Castration-Resistant Prostate Cancer  Journal Articles
• Prognostic Performance and Reproducibility of the 1973 and 2004/2016 World Health Organization Grading Classification Systems in Non–muscle-invasive Bladder Cancer: A European Association of Urology Non-muscle Invasive Bladder Cancer Guidelines Panel Systematic Review  Journal Articles
• Prognostic factors associated with mortality in acute exacerbations of idiopathic pulmonary fibrosis: A systematic review and meta-analysis  Journal Articles
• Prognostic implications of active discoid lupus erythematosus and malar rash at the time of diagnosis of systemic lupus erythematosus: Results from a prospective cohort study  Journal Articles
• Progression From Paroxysmal to Persistent Atrial Fibrillation  Journal Articles
• Progression and Management of Duodenal Neoplasia in Familial Adenomatous Polyposis  Journal Articles
• Progression of Device-Detected Subclinical Atrial Fibrillation and the Risk of Heart Failure  Journal Articles
• Progression of Liver Fibrosis and Modern Combination Antiretroviral Therapy Regimens in HIV-Hepatitis C–Coinfected Persons  Journal Articles
• Progression of Lung Disease in Preschool Patients with Cystic Fibrosis  Journal Articles
• Progression of atypical extraventricular neurocytoma to anaplastic ganglioglioma  Journal Articles
• Progression of internal carotid artery stenosis in patients with peripheral arterial occlusive disease  Journal Articles
• Progression of renal insufficiency in type 2 diabetes with and without microalbuminuria: results of the Heart Outcomes and Prevention Evaluation (HOPE) randomized study  Journal Articles
• Progression through diabetes therapies among new elderly users of metformin: a population‐based study  Journal Articles
• Progression to chronic atrial fibrillation after pacing: the Canadian Trial of Physiologic Pacing  Journal Articles
• Progressive Loss of Retinal Ganglion Cells in Activating Protein-2β Neural Crest Cell Knockout Mice  Journal Articles
• Progressive fibrosing interstitial lung disease: treatable traits and therapeutic strategies  Journal Articles
• Progressive muscle weakness: More there than meets the eye  Journal Articles
• Progressive pulmonary fibrosis: an expert group consensus statement  Journal Articles
• Progressive thrombocytopenia after cardiac surgery in a 67-year-old man  Journal Articles
• Prospective Associations of Vitamin D With β-Cell Function and Glycemia  Journal Articles
• Prospective Cohort Study of Renin-Angiotensin System Blocker Usage after Hospitalized Acute Kidney Injury  Journal Articles
• Prospective Study of Tricuspid Regurgitation Associated With Permanent Leads After Cardiac Rhythm Device Implantation  Conferences
• Prospective evaluation of the morbidity and mortality of wild-type and V122I mutant transthyretin amyloid cardiomyopathy: The Transthyretin Amyloidosis Cardiac Study (TRACS)  Journal Articles
• Prostate Cancer Lymphangitic Pulmonary Carcinomatosis  Journal Articles
• Protein Misfolding and Endoplasmic Reticulum Stress in Chronic Lung Disease  Journal Articles
• Protein Misfolding and Endoplasmic Reticulum Stress in Chronic Lung Disease  Journal Articles
• Protein Z in Ischemic Stroke and its Etiologic Subtypes  Journal Articles
• Quality of life in pediatric-onset multiple sclerosis: Different disease course, different impact, different measurement approach needed  Journal Articles
• Quality-of-Life Assessments and Chronic Liver Disease  Journal Articles
• Quantitative ⁶⁸Ga-DOTATATE PET/CT Parameters for the Prediction of Therapy Response in Patients with Progressive Metastatic Neuroendocrine Tumors Treated with ¹⁷⁷Lu-DOTATATE  Journal Articles
• Quantitative analysis of subchondral sclerosis of the tibia by bone texture parameters in knee radiographs: site-specific relationships with joint space width  Journal Articles
• Quantitative muscle analysis in facioscapulohumeral muscular dystrophy using whole‐body fat‐referenced MRI: Protocol development, multicenter feasibility, and repeatability  Journal Articles
• Radiographic progression by Prostate Cancer Working Group (PCWG)‐2 criteria as an intermediate endpoint for drug development in metastatic castration‐resistant prostate cancer  Journal Articles
• Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck  Journal Articles
• Randomised, double-blind trial of carboplatin and paclitaxel with daily oral cediranib or placebo in patients with advanced non-small cell lung cancer: NCIC Clinical Trials Group study BR29  Journal Articles
• Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy  Journal Articles
• Randomized phase II study of modified FOLFOX-6 in combination with ramucirumab or icrucumab as second-line therapy in patients with metastatic colorectal cancer after disease progression on first-line irinotecan-based therapy  Journal Articles
• Rapid access rehabilitation after exacerbations of COPD – A qualitative study  Journal Articles
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• Rapid progression of acute sciatica to cauda equina syndrome.  Journal Articles
• Rapid progression of prostate cancer in men with a BRCA2 mutation  Journal Articles
• Rapidly Progressive Dementia Due toMycobacterium neoaurumMeningoencephalitis  Journal Articles
• Rapidly progressive interstitial lung fibrosis in a patient with amyopathic dermatomyositis and anti‑MDA5 antibodies  Journal Articles
• Rationale and design features of a clinical trial examining the effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis: Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT). SCAT Investigators.  Journal Articles
• Rationale and design of a Global Rheumatic Heart Disease Registry: The REMEDY study  Journal Articles
• Rationale for and design of the Acarbose Cardiovascular Evaluation (ACE) trial  Journal Articles
• Rationale, design, and baseline characteristics of a randomized trial to assess the effect of cholesterol lowering on the progression of aortic stenosis  Journal Articles
• Real-world health care utilization and effectiveness of omalizumab for the treatment of severe asthma  Journal Articles
• Recent Developments in Imaging of Multiple Sclerosis  Journal Articles
• Recognition and repair of chemically heterogeneous structures at DNA ends  Journal Articles
• Red Cell Distribution Width as a Novel Prognostic Marker in Heart Failure  Journal Articles
• Red blood cell distribution width levels correlate with liver fibrosis and inflammation: a noninvasive serum marker panel to predict the severity of fibrosis and inflammation in patients with hepatitis B.  Journal Articles
• Redefining Cut-Points for High Symptom Burden of the Global Initiative for Chronic Obstructive Lung Disease Classification in 18,577 Patients With Chronic Obstructive Pulmonary Disease  Journal Articles
• Reduction in Pseudomonas aeruginosa sputum density during a cystic fibrosis pulmonary exacerbation does not predict clinical response  Journal Articles
• Refractory bipolar disorder and neuroprogression  Journal Articles
• Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice  Journal Articles
• Relation of Increasing QRS Duration Over Time and Cardiovascular Events in Outpatients With Heart Failure  Journal Articles
• Relation of N-terminal pro B-type natriuretic peptide to progression of aortic valve disease  Journal Articles
• Relationship of Inhaled Corticosteroid Adherence to Asthma Exacerbations in Patients with Moderate-to-Severe Asthma  Journal Articles
• Relative and absolute test–retest reliabilities of biomechanical risk factors for knee osteoarthritis progression: benchmarks for meaningful change  Journal Articles
• Relentless Progression of Venous Obstruction in a Case of Budd-Chiari Syndrome Related to Heterozygous Protein C Deficiency  Journal Articles
• Relevance of Birth Cohorts to Assessment of Asthma Persistence  Journal Articles
• Renal Interstitial Infiltration and Tertiary Lymphoid Organ Neogenesis in IgA Nephropathy  Journal Articles
• Renal Parenchyma to Hydronephrosis Area Ratio (PHAR) as a Predictor of Future Surgical Intervention for Infants With High-grade Prenatal Hydronephrosis  Journal Articles
• Reply to: Risk factors for disease progression in fibrotic hypersensitivity pneumonitis  Journal Articles
• Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis  Journal Articles
• Respiratory Syncytial Virus Immunoprophylaxis with Palivizumab: 12-Year Observational Study of Usage and Outcomes in Canada  Journal Articles
• Response to single agent PD-1 inhibitor after progression on previous PD-1/PD-L1 inhibitors: a case series  Journal Articles
• Responsiveness to change to change due to supportive-expressive group therapy, improvement in mood and disease progression in women with metastatic breast cancer  Journal Articles
• Results from the TRIBE-AKI Study found associations between post-operative blood biomarkers and risk of chronic kidney disease after cardiac surgery  Journal Articles
• Reversibility and recurrence of IGF-IR-induced mammary tumors  Journal Articles
• Riboflavin transporter deficiency mimicking mitochondrial myopathy caused by complex II deficiency  Journal Articles
• Risankizumab in Severe Asthma — A Phase 2a, Placebo-Controlled Trial  Journal Articles
• Risk Factors for Progression of Alzheimer Disease in a Canadian Population: The Canadian Outcomes Study in Dementia (COSID)  Journal Articles
• Risk Prediction for Early CKD in Type 2 Diabetes  Journal Articles
• Risk factors of new onset anxiety and anxiety exacerbation in the perinatal period: A systematic review and meta-analysis  Journal Articles
• Risk of Chronic Dialysis and Death Following Acute Kidney Injury  Journal Articles
• Risk of cardiovascular events among women with high normal blood pressure or blood pressure progression: prospective cohort study  Journal Articles
• Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis: 2-year results of a randomised trial  Journal Articles
• Role of Renin-Angiotensin System Blockade in Patients With Diabetes Mellitus  Journal Articles
• SARS-CoV-2 infection in technology-dependent children: a multicenter case series  Journal Articles
• SERAPHIN haemodynamic substudy: the effect of the dual endothelin receptor antagonist macitentan on haemodynamic parameters and NT-proBNP levels and their association with disease progression in patients with pulmonary arterial hypertension  Journal Articles
• Safe and Effective Prescription of Exercise in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Rationale and Methods for an Integrated Knowledge Translation Study  Journal Articles
• Safety of Treatment of Metastatic Breast Cancer With Trastuzumab Beyond Disease Progression  Journal Articles
• Selexipag for the Treatment of Pulmonary Arterial Hypertension  Journal Articles
• Serological Immunoreactivity against Colon Cancer Proteome Varies upon Disease Progression  Journal Articles
• Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study  Journal Articles
• Severe Exacerbations and Decline in Lung Function in Asthma  Journal Articles
• Sex dimorphism in ANGII-mediated crosstalk between ACE2 and ACE in diabetic nephropathy  Journal Articles
• Sex-Related Differences in Heart Failure With Preserved Ejection Fraction  Journal Articles
• Shock, acute disseminated intravascular coagulation, and microvascular thrombosis: is ‘shock liver’ the unrecognized provocateur of ischemic limb necrosis?  Journal Articles
• Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma  Journal Articles
• Short-term changes in arterial inflammation predict long-term changes in atherosclerosis progression  Journal Articles
• Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease  Journal Articles
• Siglec-15 promotes progression of clear renal cell carcinoma  Journal Articles
• Sildenafil for idiopathic pulmonary fibrosis: A systematic review and meta-analysis  Journal Articles
• Single-agent Taxane Versus Taxane-containing Combination Chemotherapy as Salvage Therapy for Advanced Urothelial Carcinoma  Journal Articles
• Single-agent Taxane Versus Taxane-containing Combination Chemotherapy as Salvage Therapy for Advanced Urothelial Carcinoma.  Journal Articles
• Skewing toward Treg and Th2 responses is a characteristic feature of sustained remission in ANCA‐positive granulomatosis with polyangiitis  Journal Articles
• Small rodent models of atherosclerosis  Journal Articles
• Smoking, season, and detection of chlamydia pneumoniaeDNA in clinically stable COPD patients  Journal Articles
• Socioeconomic status, blood pressure progression, and incident hypertension in a prospective cohort of female health professionals  Journal Articles
• Sodium-glucose cotransporter-2 (SGLT-2) inhibitors for adults with chronic kidney disease: a clinical practice guideline.  Journal Articles
• Somatostatin Receptor–Targeted Radiopeptide Therapy with ⁹⁰Y-DOTATOC and ¹⁷⁷Lu-DOTATOC in Progressive Meningioma: Long-Term Results of a Phase II Clinical Trial  Journal Articles
• Sputum microbiota is predictive of long-term clinical outcomes in young adults with cystic fibrosis  Journal Articles
• Staging and Neuroprogression in Bipolar Disorder  Journal Articles
• Staging and Neuroprogression in Bipolar Disorder: A Systematic Review of the Literature  Journal Articles
• Staging systems in bipolar disorder: an International Society for Bipolar Disorders Task Force Report  Journal Articles
• Standardisation of Clinical Assessment, Management and Follow-Up of Acute Hospitalised Exacerbation of COPD: A Europe-Wide Consensus  Journal Articles
• Standardizing Measurement of Chronic Obstructive Pulmonary Disease Exacerbations  Journal Articles
• Statin Therapy and Outcomes in Trials of Nintedanib in Idiopathic Pulmonary Fibrosis  Journal Articles
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• Stereologic Analysis of Tibial-Plateau Cartilage and Femoral Cancellous Bone in Guinea Pigs With Spontaneous Osteoarthritis  Journal Articles
• Stereotactic Ablative Radiotherapy for the Comprehensive Treatment of Oligometastatic Cancers: Long-Term Results of the SABR-COMET Phase II Randomized Trial  Journal Articles
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• Stereotactic ablative radiotherapy for the comprehensive treatment of 1–3 Oligometastatic tumors (SABR-COMET-3): study protocol for a randomized phase III trial  Journal Articles
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• Stroke prevention in asymptomatic carotid artery disease: revascularization of carotid stenosis is not the solution  Journal Articles
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• Stroke type and severity in patients with subclinical atrial fibrillation: An analysis from the Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial (ASSERT)  Journal Articles
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• Subclinical atrial fibrillation: The significance of progression to longer episodes  Journal Articles
• Subcutaneous emphysema of the chest: could it be pulmonary mucormycosis?  Journal Articles
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• Substantial intraindividual variability of BNP concentrations in patients with hypertension  Journal Articles
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• Surgical outcomes and natural history of intramedullary spinal cord cavernous malformations: a single-center series and meta-analysis of individual patient data  Journal Articles
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• Systematic validation of disease models for pharmacoeconomic evaluations  Journal Articles
• Systemic Sclerosis Sine Scleroderma: A Multicenter Study of 1417 Subjects  Journal Articles
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• TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis  Journal Articles
• TGF-β1 Induces Progressive Pleural Scarring and Subpleural Fibrosis  Journal Articles
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• Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study  Journal Articles
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• Temozolomide in metastatic breast cancer (MBC): a phase II trial of the National Cancer Institute of Canada – Clinical Trials Group (NCIC-CTG)  Journal Articles
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• The Effect of Widespread Pain on Knee Pain Worsening, Incident Knee Osteoarthritis (OA), and Incident Knee Pain: The Multicenter OA (MOST) Study  Journal Articles
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• The association between tumour progression and vascularity in the oral mucosa  Journal Articles
• The association of urinary sodium excretion and the need for renal replacement therapy in advanced chronic kidney disease: a cohort study  Journal Articles
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• The high risk of stroke immediately after transient ischemic attack  Journal Articles
• The impact of category, cytopathology and cytogenetics on development and progression of clonal and malignant myeloid transformation in inherited bone marrow failure syndromes  Journal Articles
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• The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey  Journal Articles
• The justification for the progressive fibrotic phenotype  Journal Articles
• The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation  Journal Articles
• The natural history of progressive fibrosing interstitial lung diseases  Journal Articles
• The potential to predict the course of childhood asthma  Journal Articles
• The potential use of biomarkers as an adjunctive tool for staging bipolar disorder  Journal Articles
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• The relationship between estimated sodium and potassium excretion and subsequent renal outcomes  Journal Articles
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• The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort  Journal Articles
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• Therapeutic targets in idiopathic pulmonary fibrosis  Journal Articles
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• Three-dimensional computed tomography imaging in an animal model of emphysema  Journal Articles
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• Trajectories and Prognostic Significance of 6-Minute Walk Test Parameters in Fibrotic Interstitial Lung Disease  Journal Articles
• Trajectories of pain severity in juvenile idiopathic arthritis: results from the Research in Arthritis in Canadian Children Emphasizing Outcomes cohort  Journal Articles
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• Treatment of idiopathic pulmonary fibrosis with Nintedanib: an update  Journal Articles
• Treatment of idiopathic pulmonary fibrosis: an update on emerging drugs in phase II & III clinical trials  Journal Articles
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• Trends in the Incidence of New-Onset Anorexia Nervosa and Atypical Anorexia Nervosa Among Youth During the COVID-19 Pandemic in Canada  Journal Articles
• Triaging Herpes Zoster Ophthalmicus Patients in the Emergency Department: Do All Patients Require Referral?  Journal Articles
• Tumor protein expression of the DNA repair gene BRCA1 and lethal prostate cancer  Journal Articles
• Tumour necrosis is an independent prognostic marker in non-small cell lung cancer: correlation with biological variables  Journal Articles
• Ultrashort-specific immunotherapy successfully treats seasonal allergic rhinoconjunctivitis to grass pollen  Journal Articles
• Ultrasound examination predicts 6‐month progression in carpal tunnel syndrome patients  Journal Articles
• Unfavourable effects of medically indicated oral anticoagulants on survival in idiopathic pulmonary fibrosis  Journal Articles
• Upregulation of FAM84B during prostate cancer progression  Journal Articles
• Urate lowering therapy to improve renal outcomes in patients with chronic kidney disease: systematic review and meta-analysis  Journal Articles
• Urinary EGF and MCP-1 and risk of CKD after cardiac surgery  Journal Articles
• Urine Volume and Change in Estimated GFR in a Community-Based Cohort Study  Journal Articles
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• Using the life course perspective to study the entry into the illness trajectory: The perspective of caregivers of people with Alzheimer's disease  Journal Articles
• Validation of Visual Caries Activity Assessment  Journal Articles
• Valsartan combined with clopidogrel and/or leflunomide for the treatment of progressive immunoglobulin A nephropathy  Journal Articles
• Value of Repeated Cardiac Magnetic Resonance Imaging in Patients with Suspected Arrhythmogenic Right Ventricular Cardiomyopathy  Journal Articles
• Variants of the SFTPA1 and SFTPA2 genes and susceptibility to tuberculosis in Ethiopia  Journal Articles
• Verbal episodic memory along the course of schizophrenia and bipolar disorder: A new perspective  Journal Articles
• Vertebral Fractures: Which Radiological Criteria Are Better Associated With the Clinical Course of Osteoporosis?  Journal Articles
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• Waiting for hip revision surgery: the impact on patient disability.  Journal Articles
• What Does Early Antisocial Behaviour Predict? A Follow-up of 4- and 5-Year-Olds from the Ontario Child Health Study  Journal Articles
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• When are biomarkers useful in the management of airway diseases?  Journal Articles
• When to perform gastroscopy in the PSC patient  Journal Articles
• White Matter Hyperintensities and Blood Pressure Lowering in Acute Intracerebral Hemorrhage: A Secondary Analysis of the ATACH-2 Trial  Journal Articles
• White matter volume is decreased in bipolar disorder at early and late stages  Journal Articles
• Worsening Renal Function and Outcome in Heart Failure Patients With Preserved Ejection Fraction and the Impact of Angiotensin Receptor Blocker Treatment  Journal Articles
• Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker treatment: data from the CHARM‐study programme  Journal Articles
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• [Bipolar disorder: staging and neuroprogression].  Journal Articles
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• α₁-Antitrypsin Deficiency Alleles in Cystic Fibrosis Lung Disease  Journal Articles
• “You Take This Day by Day, Come What May”: A Qualitative Study of the Psychosocial Impacts of Living with Duchenne Muscular Dystrophy  Journal Articles