Journal article
How to define responders in osteoarthritis
Abstract
BACKGROUND: Osteoarthritis is a clinical syndrome of failure of the joint accompanied by varying degrees of joint pain, functional limitation, and reduced quality of life due to deterioration of articular cartilage and involvement of other joint structures.
SCOPE: Regulatory agencies require relevant clinical benefit on symptoms and structure modification for registration of a new therapy as a disease-modifying osteoarthritis drug (DMOAD). An …
Authors
Cooper C; Adachi JD; Bardin T; Berenbaum F; Flamion B; Jonsson H; Kanis JA; Pelousse F; Lems WF; Pelletier J-P
Journal
Current Medical Research and Opinion, Vol. 29, No. 6, pp. 719–729
Publisher
Taylor & Francis
Publication Date
June 1, 2013
DOI
10.1185/03007995.2013.792793
ISSN
0300-7995