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Plasma cell proliferative index is an independent...
Journal article

Plasma cell proliferative index is an independent predictor of progression in smoldering multiple myeloma

Abstract

The plasma cell proliferative index (PCPI), determined by a slide technique or by flow cytometry, detects cells in the S phase of the cell cycle and is a useful prognostic tool in patients with plasma cell disorders such as multiple myeloma and amyloidosis. We conducted a retrospective review analyzing the prognostic effect of PCPI in 306 patients with smoldering multiple myeloma (SMM). Seventy-nine (26%) patients had an elevated PCPI (>0.5). …

Authors

Aljama MA; Sidiqi MH; Lakshman A; Dispenzieri A; Jevremovic D; Gertz MA; Lacy MQ; Buadi FK; Dingli D; Muchtar E

Journal

Blood Advances, Vol. 2, No. 22, pp. 3149–3154

Publisher

American Society of Hematology

Publication Date

November 27, 2018

DOI

10.1182/bloodadvances.2018024794

ISSN

2473-9529