Journal article
Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma
Abstract
BACKGROUND: Glioblastoma is associated with a poor prognosis in the elderly. Survival has been shown to increase among patients 70 years of age or younger when temozolomide chemotherapy is added to standard radiotherapy (60 Gy over a period of 6 weeks). In elderly patients, more convenient shorter courses of radiotherapy are commonly used, but the benefit of adding temozolomide to a shorter course of radiotherapy is unknown.
METHODS: We …
Authors
Perry JR; Laperriere N; O'Callaghan CJ; Brandes AA; Menten J; Phillips C; Fay M; Nishikawa R; Cairncross JG; Roa W
Journal
The New England Journal of Medicine, Vol. 376, No. 11, pp. 1027–1037
Publisher
Massachusetts Medical Society
Publication Date
March 16, 2017
DOI
10.1056/nejmoa1611977
ISSN
0028-4793