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HDL Cholesterol, LDL Cholesterol, and...

Journal article

HDL Cholesterol, LDL Cholesterol, and Triglycerides as Risk Factors for CKD: A Mendelian Randomization Study

Abstract

BACKGROUND: High-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, and triglyceride concentrations are heritable risk factors for vascular disease, but their role in the progression of chronic kidney disease (CKD) is unclear. STUDY DESIGN: 2-sample Mendelian randomization analysis of data derived from the largest published lipid and CKD studies.

Authors

Lanktree MB; Thériault S; Walsh M; Paré G

Journal

American Journal of Kidney Diseases, Vol. 71, No. 2, pp. 166–172

Publisher

Elsevier

Publication Date

2 2018

DOI

10.1053/j.ajkd.2017.06.011

ISSN

0272-6386

Associated Experts

Guillaume Pare

Professor, Faculty of Health Sciences

Matthew Lanktree

Associate Professor, Faculty of Health Sciences

Michael Walsh

Associate Professor, Faculty of Health Sciences

Labels

Fields of Research (FoR)

32 Biomedical and Clinical Sciences 3202 Clinical sciences

Medical Subject Headings (MeSH)

Albuminuria Causality Cholesterol, HDL Cholesterol, LDL Correlation of Data Disease Progression Genetic Pleiotropy Genetic Predisposition to Disease Genetic Variation Genome-Wide Association Study Glomerular Filtration Rate Humans Mendelian Randomization Analysis Renal Insufficiency, Chronic Triglycerides

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