Journal article
Plasma pro-surfactant protein B and lung function decline in smokers
Abstract
Plasma pro-surfactant protein B (pro-SFTPB) levels have recently been shown to predict the development of lung cancer in current and ex-smokers, but the ability of pro-SFTPB to predict measures of chronic obstructive pulmonary disease (COPD) severity is unknown. We evaluated the performance characteristics of pro-SFTPB as a biomarker of lung function decline in a population of current and ex-smokers. Plasma pro-SFTPB levels were measured in …
Authors
Leung JM; Mayo J; Tan W; Tammemagi CM; Liu G; Peacock S; Shepherd FA; Goffin J; Goss G; Nicholas G
Journal
European Respiratory Journal, Vol. 45, No. 4, pp. 1037–1045
Publisher
European Respiratory Society (ERS)
Publication Date
April 2015
DOI
10.1183/09031936.00184214
ISSN
0903-1936
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AgedBiomarkersCanadaCohort StudiesDisease ProgressionFemaleForced Expiratory Flow RatesHumansLinear ModelsMaleMiddle AgedMultivariate AnalysisProtein PrecursorsPulmonary Disease, Chronic ObstructivePulmonary Surfactant-Associated ProteinsPulmonary SurfactantsRespiratory Function TestsRetrospective StudiesSeverity of Illness IndexSmokingSpirometry