Journal article
Limited Protective Effect of the CCR5Δ32/CCR5Δ32 Genotype on Human Immunodeficiency Virus Infection Incidence in a Cohort of Patients with Hemophilia and Selection for Genotypic X4 Virus
Abstract
The relationship among CCR5 genotype, cytomegalovirus infection, and disease progression and death was studied among 159 human immunodeficiency virus (HIV)-infected patients with hemophilia. One patient (0.6%) had the CCR5Delta32/CCR5Delta32 genotype (which occurs in approximately 2% of the Scandinavian population) and a rapid disease course. His HIV V3 region contained genotypic features attributable to X4 virus and resembled functionally …
Authors
Iversen AKN; Christiansen CB; Attermann J; Eugen-Olsen J; Schulman S; Berntorp E; Ingerslev J; Fugger L; Scheibel E; Tengborn L
Journal
The Journal of Infectious Diseases, Vol. 187, No. 2, pp. 215–225
Publisher
Oxford University Press (OUP)
Publication Date
January 15, 2003
DOI
10.1086/345881
ISSN
0022-1899