Journal article
Development of Renal Disease in People at High Cardiovascular Risk: Results of the HOPE Randomized Study
Abstract
In people with diabetes, renal disease tends to progress from microalbuminuria to clinical proteinuria to renal insufficiency. Little evidence has been published for the nondiabetic population. This study retrospectively analyzed changes of proteinuria over 4.5 yr in the HOPE (Heart Outcomes and Prevention Evaluation) study, which compared ramipril's effects to placebo in 9297 participants, including 3577 with diabetes and 1956 with …
Authors
Mann JFE; Gerstein HC; Yi Q-L; Lonn EM; Hoogwerf BJ; Rashkow A; Yusuf S
Journal
Journal of the American Society of Nephrology, Vol. 14, No. 3, pp. 641–647
Publisher
Wolters Kluwer
Publication Date
March 2003
DOI
10.1097/01.asn.0000051594.21922.99
ISSN
1046-6673