Journal article
Ndel1 oligopeptidase activity as a potential biomarker of early stages of schizophrenia
Abstract
Our previous studies showed reduced Ndel1 enzyme activity in patients with chronic schizophrenia (SCZ), and only a subtle NDEL1 mRNA increases in antipsychotic-naïve first-episode psychosis (FEP) individuals compared to matched healthy controls (HC). Aiming to refine the evaluation of Ndel1 enzyme activity in early stages of psychosis, we compared 3 groups composed by (1) subjects at ultra-high-risk (UHR) for psychosis, (2) a cohort comprising …
Authors
Dal Mas C; Nani JV; Noto C; Yonamine CM; da Cunha GR; Mansur RB; Ota VK; Belangero SI; Cordeiro Q; Kapczinski F
Journal
Schizophrenia Research, Vol. 208, , pp. 202–208
Publisher
Elsevier
Publication Date
June 2019
DOI
10.1016/j.schres.2019.02.021
ISSN
0920-9964