Journal article
Gemcitabine concurrent with continuous infusional 5-fluorouracil in advanced biliary cancers: a review of the Princess Margaret Hospital experience
Abstract
BACKGROUND: Unresectable biliary tract cancer has a very poor prognosis. A combination of weekly gemcitabine plus continuous infusional 5-fluorouracil (5-FU) (GEM/CVI 5-FU) was evaluated as therapy for this cancer.
PATIENTS AND METHODS: The charts of 27 patients with advanced biliary tract adenocarcinoma treated with GEM/CVI 5-FU at the Princess Margaret Hospital were evaluated for response, survival and toxicity. The treatment consisted of a …
Authors
Knox JJ; Hedley D; Oza A; Siu LL; Pond GR; Moore MJ
Journal
Annals of Oncology, Vol. 15, No. 5, pp. 770–774
Publisher
Elsevier
Publication Date
May 2004
DOI
10.1093/annonc/mdh172
ISSN
0923-7534
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdenocarcinomaAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBile Duct NeoplasmsBile Ducts, IntrahepaticCholangiocarcinomaDeoxycytidineDisease ProgressionDrug Administration ScheduleFemaleFluorouracilGallbladder NeoplasmsHumansInfusions, IntravenousMaleMiddle AgedPrognosisRetrospective StudiesSurvival AnalysisTreatment OutcomeGemcitabine