Journal article
Exacerbation frequency and clinical outcomes in adult patients with cystic fibrosis
Abstract
BACKGROUND: Despite advances in treatment of cystic fibrosis (CF), pulmonary exacerbations remain common. The aim of this study was to determine if frequent pulmonary exacerbations are associated with greater declines in lung function, or an accelerated time to death or lung transplantation in adults with CF.
METHODS: A 3-year prospective cohort study was conducted on 446 adult patients with CF from Ontario, Canada who could spontaneously …
Authors
de Boer K; Vandemheen KL; Tullis E; Doucette S; Fergusson D; Freitag A; Paterson N; Jackson M; Lougheed MD; Kumar V
Journal
Thorax, Vol. 66, No. 8,
Publisher
BMJ
Publication Date
August 1, 2011
DOI
10.1136/thx.2011.161117
ISSN
0040-6376