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Nintedanib and immunomodulatory therapies in...
Journal article

Nintedanib and immunomodulatory therapies in progressive fibrosing interstitial lung diseases

Abstract

BackgroundIn the INBUILD trial in patients with chronic fibrosing interstitial lung diseases (ILDs) and a progressive phenotype, nintedanib reduced the rate of ILD progression with adverse events that were manageable for most patients. We investigated the potential impact of immunomodulatory therapies on the efficacy and safety of nintedanib.MethodsSubjects with fibrosing ILDs other than idiopathic pulmonary fibrosis, who had shown progression …

Authors

Cottin V; Richeldi L; Rosas I; Otaola M; Song JW; Tomassetti S; Wijsenbeek M; Schmitz M; Coeck C; Stowasser S

Journal

Respiratory Research, Vol. 22, No. 1,

Publisher

Springer Nature

Publication Date

December 2021

DOI

10.1186/s12931-021-01668-1

ISSN

1465-9921