A stochastic approach to risk management for prostate cancer patients on active surveillance

Screening for prostate cancer (PC) has led to more cancers being detected at early stages, where active surveillance (AS), a strategy that involves monitoring and intervention when the disease progresses, is an option. Physicians are seeking ways to measure progression of the disease such that AS is abandoned when appropriate. A blood test, prostate-specific antigen (PSA), and the concept of doubling time (PSADT) and PSA kinetics are being used …