Immune Responses to the Mycobacterium tuberculosis -Specific Antigen ESAT-6 Signal Subclinical Infection among Contacts of Tuberculosis Patients Journal Articles uri icon

  •  
  • Overview
  •  
  • Research
  •  
  • Identity
  •  
  • Additional Document Info
  •  
  • View All
  •  

abstract

  • ABSTRACT Diagnosis of latent Mycobacterium tuberculosis infection is considered essential for tuberculosis control but is hampered by the lack of specific reagents. We report that strong recognition of tuberculosis complex-specific antigen ESAT-6 by healthy household contacts of tuberculosis patients correlates with the subsequent development of active tuberculosis during a 2-year follow-up period.

authors

  • Doherty, T Mark
  • Demissie, Abebech
  • Olobo, Joseph
  • Wolday, Dawit
  • Britton, Sven
  • Eguale, Tewodros
  • Ravn, Pernille
  • Andersen, Peter

publication date

  • February 2002