Prevention of Chronic Kidney Disease and Subsequent Effect on Mortality: A Systematic Review and Meta-Analysis

OBJECTIVES: To perform a systematic review of randomized controlled trials to determine whether prevention or slowing of progression of chronic kidney disease would translate into improved mortality, and if so, the attributable risk due to CKD itself on mortality. BACKGROUND: CKD is associated with increased mortality. This association is largely based on evidence from the observational studies and evidence from randomized controlled trials is …