Journal article
Intra-articular hyaluronate in experimental rabbit osteoarthritis can prevent changes in cartilage proteoglycan content11Supported by the Department of Trade and Industry (UK), the Scottish Home and Health Department, the Wellcome Trust and the University of Edinburgh.
Abstract
OBJECTIVE: The purpose of this study was to determine the effects of intra-articular injections of high molecular weight (2000 kDa) sodium hyaluronate (HA) on the progression of articular cartilage degeneration in a rabbit partial medial meniscectomy model of osteoarthritis.
DESIGN: Six experimental groups included normal, sham operated, and operated and injected animals, the latter injected once-weekly (for two weeks or twelve weeks, beginning …
Authors
Hulmes DJS; Marsden ME; Strachan RK; Harvey RE; McInnes N; Gardner DL
Journal
Osteoarthritis and Cartilage, Vol. 12, No. 3, pp. 232–238
Publisher
Elsevier
Publication Date
March 2004
DOI
10.1016/j.joca.2003.11.007
ISSN
1063-4584