Drug Administration Schedule - McMaster Experts

subject area of

10 Anticoagulant therapy in venous thromboembolism Academic Article
14 day endoscopy study comparing risedronate and alendronate in postmenopausal women stratified by Helicobacter pylori status. Academic Article
20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years Academic Article
25-Hydroxyvitamin D Concentrations in Children with Crohn's Disease Supplemented with Either 2000 or 400 IU Daily for 6 Months: A Randomized Controlled Study Academic Article
7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial Academic Article
Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia Academic Article
In vitro disintegration studies of weekly generic and branded risedronate sodium formulations available in Canada Academic Article
d-Dimer Testing to Determine the Duration of Anticoagulation Therapy Academic Article
A 24-Week, Randomized, Treat-to-Target Trial Comparing Initiation of Insulin Glargine Once-Daily With Insulin Detemir Twice-Daily in Patients With Type 2 Diabetes Inadequately Controlled on Oral Glucose-Lowering Drugs Academic Article
A 26-week, prospective, open-label, uncontrolled, multicenter study to evaluate the effect of an escalating-dose regimen of trandolapril on change in blood pressure in treatment-naive and concurrently treated adult hypertensive subjects (TRAIL) Academic Article
A Canadian survey of self-infusion practices in persons with haemophilia A Academic Article
A Comparison of Three Months of Anticoagulation with Extended Anticoagulation for a First Episode of Idiopathic Venous Thromboembolism Academic Article
A Double-Blind Randomized Controlled Trial of Augmentation and Switch Strategies for Refractory Social Anxiety Disorder Academic Article
A Double-Blind, Randomized, Placebo-Controlled 4-Week Study on the Efficacy and Safety of the Purinergic Agents Allopurinol and Dipyridamole Adjunctive to Lithium in Acute Bipolar Mania Academic Article
A Genome-Wide Association Study Identifies a Novel Major Locus for Glycemic Control in Type 1 Diabetes, as Measured by Both A1C and Glucose Academic Article
A Long-term Study of the Antiinflammatory Effect of Low-dose Budesonide Plus Formoterol versus High-dose Budesonide in Asthma Academic Article
A Multicenter Phase II Clinical Trial of Lapatinib (GW572016) in Hormonally Untreated Advanced Prostate Cancer Academic Article
A Phase 1 Study of Mapatumumab (Fully Human Monoclonal Antibody to TRAIL-R1) in Patients with Advanced Solid Malignancies Academic Article
A Phase I Evaluation of Oral CI-1033 in Combination with Paclitaxel and Carboplatin as First-Line Chemotherapy in Patients with Advanced Non-small Cell Lung Cancer Academic Article
A Phase III Randomized Trial of the Timing of Meloxicam With Iodine-125 Prostate Brachytherapy Academic Article
A Pilot Study of Hypofractionated Stereotactic Radiation Therapy and Sunitinib in Previously Irradiated Patients With Recurrent High-Grade Glioma Academic Article
A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock Academic Article
A Randomized Phase II Study of Two Schedules of Bryostatin-1 (NSC339555) in Patients with Advanced Malignant Melanoma – A National Cancer Institute of Canada Clinical Trials Group Study Academic Article
A Randomized Trial Comparing 5-mg and 10-mg Warfarin Loading Doses Academic Article
A Randomized Trial of a Single Bolus Dosage Regimen of Recombinant Tissue Plasminogen Activator in Patients with Acute Pulmonary Embolism Academic Article
A Randomized, Double-Blind, Crossover Comparison of the Efficacy and Safety of Oral Controlled-Release Tramadol and Placebo in Patients with Painful Osteoarthritis Academic Article
A comparison of 30-day versus 90-day proton pump inhibitor therapy in prevention of marginal ulcers after laparoscopic Roux-en-Y gastric bypass Academic Article
A dose escalation study of YM150, an oral direct factor Xa inhibitor, in the prevention of venous thromboembolism in elective primary hip replacement surgery Academic Article
A double-blind randomized study comparing different dose regimens of H2-receptor antagonists on 24-hour gastric secretion in normal subjects and duodenal ulcer patients. Academic Article
A fatal case of Pneumocystis jirovecii pneumonia in a breast cancer patient receiving weekly paclitaxel and trastuzumab Academic Article
A multicentre randomised assessment of the DAWN AC computer-assisted oral anticoagulant dosage program Academic Article
A phase I study of obatoclax mesylate, a Bcl-2 antagonist, plus topotecan in solid tumor malignancies Academic Article
A phase I trial of two sequence-specific schedules of decitabine and vorinostat in patients with acute myeloid leukemia Academic Article
A phase II study of SB939, a novel pan-histone deacetylase inhibitor, in patients with translocation-associated recurrent/metastatic sarcomas—NCIC-CTG IND 200 Academic Article
A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer Academic Article
A pooled data analysis on the use of intermittent cyclical etidronate therapy for the prevention and treatment of corticosteroid induced bone loss. Academic Article
A prognostic factor index for overall survival in patients receiving first-line chemotherapy for HER2-negative advanced breast cancer: An analysis of the ATHENA trial Academic Article
A prospective study of an aggressive warfarin dosing algorithm to reach and maintain INR 2 to 3 after heart valve surgery Academic Article
A randomised comparison of melphalan with prednisone or dexamethasone as induction therapy and dexamethasone or observation as maintenance therapy in multiple myeloma: NCIC CTG MY.7 Academic Article
A randomised trial of 4- versus 12-weekly administration of bone-targeted agents in patients with bone metastases from breast or castration-resistant prostate cancer Academic Article
A randomized clinical trial comparing physician-directed or fixed-dose steroid replacement strategies for incomplete dexamethasone dosing prior to docetaxel chemotherapy Academic Article
A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leukemia: a NCIC (National Cancer Institute of Canada) Clinical Trials Group Study Academic Article
A randomized placebo-controlled study of tamoxifen after adjuvant chemotherapy in premenopausal women with early breast cancer (National Cancer Institute of Canada—Clinical Trials Group Trial, MA.12) Academic Article
A randomized study of alpha-interferon plus ribavirin for 6 months or 12 months for the treatment of chronic hepatitis C in patients with bleeding disorders Academic Article
A randomized trial comparing 12 weeks versus 36 weeks of adjuvant chemotherapy in stage II breast cancer. Academic Article
A randomized trial comparing activated thromboplastin time with heparin assay in patients with acute venous thromboembolism requiring large daily doses of heparin Academic Article
A randomized trial measuring fecal blood loss after treatment with rofecoxib, ibuprofen, or placebo in healthy subjects Academic Article
A randomized trial of Pegaptanib sodium for age-related macular degeneration used an innovative design to explore disease-modifying effects Academic Article
A randomized, controlled, dose-guiding study of the oral direct thrombin inhibitor ximelagatran compared with standard therapy for the treatment of acute deep vein thrombosis: THRIVE I Academic Article
A single dose of aprotinin prevents platelet hyporeactivity after coronary artery bypass graft surgery Academic Article
A therapeutic time window for anti-CD11d monoclonal antibody treatment yielding reduced secondary tissue damage and enhanced behavioral recovery following severe spinal cord injury Academic Article
A weekly 35,000 IU vitamin D supplementation improves bone turnover markers in vitamin D deficient Saudi adolescent females Academic Article
AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment Academic Article
Abiraterone acetate for patients with metastatic castration-resistant prostate cancer progressing after chemotherapy: final analysis of a multicentre, open-label, early-access protocol trial Academic Article
Acid suppression in duodenal ulcer: a meta-analysis to define optimal dosing with antisecretory drugs. Academic Article
Acid-Suppressive Therapy With Esomeprazole for Relief of Unexplained Chest Pain in Primary Care: A Randomized, Double-Blind, Placebo-Controlled Trial Academic Article
Active metabolite concentration of clopidogrel in patients taking different doses of aspirin: results of the interaction trial Academic Article
Activity of intravenous menogaril in patients with previously untreated metastatic breast cancer Academic Article
Acupuncture-Like Transcutaneous Electrical Nerve Stimulation Versus Pilocarpine in Treating Radiation-Induced Xerostomia: Results of RTOG 0537 Phase 3 Study Conference Paper
Acute Treatment of Bipolar Depression with Gabapentin Academic Article
Addition of verapamil and tamoxifen to the initial chemotherapy of small cell lung cancer a phase I/II study Academic Article
Adipogenic and lipolytic effects of chronic glucocorticoid exposure Academic Article
Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial Academic Article
Adjustable Maintenance Dosing with Budesonide/Formoterol Reduces Asthma Exacerbations Compared with Traditional Fixed Dosing: A Five-Month Multicentre Canadian Study Academic Article
Adjusted dose continuous infusion of factor VIII in patients with haemophilia A Academic Article
Adjuvant Lapatinib and Trastuzumab for Early Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer: Results From the Randomized Phase III Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization Trial Academic Article
Adjuvant and extended adjuvant use of aromatase inhibitors: Reducing the risk of recurrence and distant metastasis Academic Article
Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials Academic Article
Adjuvant therapy for early breast cancer: where do we stand today? Academic Article
Adult and Pediatric Antibiotic Prophylaxis during Vascular and IR Procedures: A Society of Interventional Radiology Practice Parameter Update Endorsed by the Cardiovascular and Interventional Radiological Society of Europe and the Canadian Association for Interventional Radiology Academic Article
Advanced Ovarian Cancer: Phase III Randomized Study of Sequential Cisplatin–Topotecan and Carboplatin–Paclitaxel vs Carboplatin–Paclitaxel Academic Article
Aerosol salbutamol administration by IPPB: lowest effective dose. Academic Article
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial Academic Article
Albuterol via Turbuhaler Versus Albuterol via Pressurized Metered-Dose Inhaler in Asthma Academic Article
Alemtuzumab and CHOP Chemotherapy for the Treatment of Aggressive Histology Peripheral T Cell Lymphomas: A Multi-Center Phase I Study Academic Article
Alendronate Once Weekly for the Prevention and Treatment of Bone Loss in Canadian Adult Cystic Fibrosis Patients (CFOS Trial) Academic Article
Alendronate for osteoporosis. Safe and efficacious nonhormonal therapy. Academic Article
Alpha-Blocker Use and the Risk of Hypotension and Hypotension-Related Clinical Events in Women of Advanced Age Academic Article
American Heart Association/American College of Cardiology Foundation guide to warfarin therapy11The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the writing panel. Specifically, all members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest.This statement has been co-published in the April 1, 2003, issue of Circulation.This statement was approved by the American Heart Association Science Advisory and Coordinating Committee in October 2002 and by the American College of Cardiology Board of Trustees in February 2003. A single reprint is available by calling 800-242-8721 (US only) or writing the American Heart Association, Public Information, 7272 Greenville Ave, Dallas, TX 75231-4596. Ask for reprint No. 71-0254. To purchase additional reprints: up to 999 copies, call 800-611-6083 (US only) or fax 413-665-2671; 1000 or more copies, call 410-528-4426, fax 410-528-4264, or e-mail klbradle@lww.com. To make photocopies for personal or educational use, call the Copyright Clearance Center, 978-750-8400. Academic Article
American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients Academic Article
An Open Trial of Topiramate in the Treatment of Generalized Social Phobia Academic Article
An evaluation of several biochemical markers for bone formation and resorption in a protocol utilizing cyclical parathyroid hormone and calcitonin therapy for osteoporosis. Academic Article
Analysis of dose intensity for adjuvant chemotherapy trials in stage II breast cancer. Academic Article
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in atherosclerosis Academic Article
Anti-inflammatory effects of once daily low dose inhaled ciclesonide in mild to moderate asthmatic patients Academic Article
Antibiotic Review Kit for Hospitals (ARK-Hospital): study protocol for a stepped-wedge cluster-randomised controlled trial Academic Article
Anticoagulant therapy after acute myocardial infarction Academic Article
Anticoagulation Control with Daily Low-Dose Vitamin K to Reduce Clinically Adverse Outcomes and International Normalized Ratio Variability: A Systematic Review and Meta-Analysis Academic Article
Anticoagulation therapy in patients with prosthetic heart valves. Academic Article
Antidepressant Monotherapy vs Sequential Pharmacotherapy and Mindfulness-Based Cognitive Therapy, or Placebo, for Relapse Prophylaxis in Recurrent Depression Academic Article
Antidepressants Attenuate Increased Susceptibility to Colitis in a Murine Model of Depression Academic Article
Antihypertensive Medication Use, Adherence, Stops, and Starts in Canadians With Hypertension Academic Article
Antihypertensive effect of gamma-linolenic acid in spontaneously hypertensive rats. Academic Article
Antimanic Response to Aripiprazole in Bipolar I Disorder Patients Is Independent of the Agitation Level at Baseline Academic Article
Antiretroviral treatment change among HIV, hepatitis B virus and hepatitis C virus co-infected patients in the Australian HIV Observational Database Academic Article
Antithrombin alfa in hereditary antithrombin deficient patients: A phase 3 study of prophylactic intravenous administration in high risk situations Academic Article
Antithrombotic Therapy With Fondaparinux in Relation to Interventional Management Strategy in Patients With ST- and Non–ST-Segment Elevation Acute Coronary Syndromes Academic Article
Antithrombotic Therapy in Neonates and Children Academic Article
Antithrombotic Therapy in Patients With Saphenous Vein and Internal Mammary Artery Bypass Grafts Academic Article
Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report Academic Article
Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based clinical practice guidelines Academic Article
Antiviral activity and safety of aplaviroc, a CCR5 antagonist, in combination with lopinavir/ritonavir in HIV-infected, therapy-naïve patients: results of the EPIC study (CCR100136) Academic Article
Anti‐PF4/heparin antibody formation postorthopedic surgery thromboprophylaxis: the role of non‐drug risk factors and evidence for a stoichiometry‐based model of immunization Academic Article
Apatorsen plus docetaxel versus docetaxel alone in platinum-resistant metastatic urothelial carcinoma (Borealis-2) Academic Article
Apixaban versus Enoxaparin for Thromboprophylaxis in Medically Ill Patients Academic Article
Approach to managing musculoskeletal pain: acetaminophen, cyclooxygenase-2 inhibitors, or traditional NSAIDs? Academic Article
Aqueous Humor Cytokine Levels and Anatomic Response to Intravitreal Ranibizumab in Diabetic Macular Edema Academic Article
Aqueous beclomethasone diproprionate nasal spray: Regular versus “as required” use in the treatment of seasonal allergic rhinitis Academic Article
Ardeparin Sodium for Extended Out-of-Hospital Prophylaxis against Venous Thromboembolism after Total Hip or Knee Replacement Academic Article
Argatroban Anticoagulation in Patients With Heparin-Induced Thrombocytopenia Academic Article
Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials Academic Article
As-Needed Budesonide–Formoterol versus Maintenance Budesonide in Mild Asthma Academic Article
Aspirin Versus Low-Molecular-Weight Heparin for Extended Venous Thromboembolism Prophylaxis After Total Hip Arthroplasty Academic Article
Aspirin and clopidogrel in patients with ACS undergoing PCI: CURE and PCI-CURE. Academic Article
Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery Academic Article
Assessment of Outpatient Treatment of Deep-Vein Thrombosis With Low-Molecular-Weight Heparin Academic Article
Assessment of Quality of Life in MA.17: A Randomized, Placebo-Controlled Trial of Letrozole After 5 Years of Tamoxifen in Postmenopausal Women Academic Article
Assessment of the afferent vagal nerve in patients with gastroesophageal reflux Academic Article
Association between timing of zoledronic acid infusion and hip fracture healing Academic Article
Asthma and beta agonists. Academic Article
Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) randomised clinical trial: study protocol Academic Article
Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial Academic Article
Beneficial Effects of Gonadotropin-Releasing Hormone Analogue Treatment on Positive and Negative Symptoms of Schizophrenia Academic Article
Betrixaban (PRT054021): pharmacology, dose selection and clinical studies Academic Article
Bilateral hippocampal volume increases after long-term lithium treatment in patients with bipolar disorder: a longitudinal MRI study Academic Article
Bismuth-Based Quadruple Therapy Using a Single Capsule of Bismuth Biskalcitrate, Metronidazole, and Tetracycline Given With Omeprazole Versus Omeprazole, Amoxicillin, and Clarithromycin for Eradication of Helicobacter pylori in Duodenal Ulcer Patients: a Prospective, Randomized, Multicenter, North American Trial Academic Article
Bismuth-Based Quadruple Therapy with Bismuth Subcitrate, Metronidazole, Tetracycline and Omeprazole in the Eradication ofHelicobacter pylori Academic Article
Bisphosphonate drug holidays: we reap what we sow Academic Article
Bleeding and antidotes in new oral anticoagulants Academic Article
Bortezomib Is Active in Patients With Untreated or Relapsed Waldenström's Macroglobulinemia: A Phase II Study of the National Cancer Institute of Canada Clinical Trials Group Academic Article
Brief Communication: Preoperative Anticoagulant Activity after Bridging Low-Molecular-Weight Heparin for Temporary Interruption of Warfarin Academic Article
Buspirone augmentation of selective serotonin reuptake inhibitors (SSRIs) in social phobia Academic Article
C.E.R.A. Maintains Stable Control of Hemoglobin in Patients with Chronic Kidney Disease on Dialysis when Administered Once Every Two Weeks Academic Article
COMPARISON OF DAILY AND TWICE-WEEKLY REGIMENS TO TREAT PULMONARY TUBERCULOSIS Academic Article
Can Montelukast Shorten Prednisolone Therapy in Children with Mild to Moderate Acute Asthma? A Randomized Controlled Trial Academic Article
Can an antimicrobial stewardship program reduce length of stay of immune-competent adult patients admitted to hospital with diagnosis of community-acquired pneumonia? Study protocol for pragmatic controlled non-randomized clinical study Academic Article
Can we differentiate the low-molecular-weight heparins? Academic Article
Canadian Cancer Trials Group IND197: a phase II study of foretinib in patients with estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2-negative recurrent or metastatic breast cancer Academic Article
Canadian Cardiovascular Society Atrial Fibrillation Guidelines 2010: Rate and Rhythm Management Academic Article
Canadian clinical practice guidelines for acute and chronic rhinosinusitis. Conference Paper
Canadian multi-institutional survey of immune tolerance therapy (ITT) - experience with the use of recombinant factor VIII for ITT Academic Article
Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients Academic Article
Cannabis for pain in orthopedics: a systematic review focusing on study methodology Academic Article
Cardiovascular effects and safety of long-term colchicine treatment: Cochrane review and meta-analysis Academic Article
Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF Academic Article
Celivarone for Maintenance of Sinus Rhythm and Conversion of Atrial Fibrillation/Flutter Academic Article
Central venous access device insertion and perioperative management of patients with severe haemophilia A Academic Article
Cerebrospinal fluid to brain transport of manganese in a non-human primate revealed by MRI Academic Article
Characteristics and Outcomes in Patients with Venous Thromboembolism Taking Concomitant Anti-Platelet Agents and Anticoagulants in the AMPLIFY Trial Academic Article
Chemotherapy for Older Patients with Newly Diagnosed, Advanced-Stage, Aggressive-Histology Non-Hodgkin Lymphoma Academic Article
Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 1 Academic Article
Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 2 Academic Article
Chronic Exposure to Innocuous Antigen in Sensitized Mice Leads to Suppressed Airway Eosinophilia That Is Reversed by Granulocyte Macrophage Colony-Stimulating Factor Academic Article
Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus Academic Article
Chronic lead exposure induces ultrastructural alterations in the monkey testis. Academic Article
Chronic peripheral administration of corticotropin-releasing factor causes colonic barrier dysfunction similar to psychological stress Academic Article
Circadian pattern of acute, neuroleptic-induced dystonic reactions Academic Article
Clinical Impact of Bleeding in Patients Taking Oral Anticoagulant Therapy for Venous Thromboembolism Academic Article
Clinical Impact of Double Protease Inhibitor Boosting with Lopinavir/Ritonavir and Amprenavir as Part of Salvage Antiretroviral Therapy Academic Article
Clinical Outcomes Associated With Procalcitonin Algorithms to Guide Antibiotic Therapy in Respiratory Tract Infections Academic Article
Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer Academic Article
Clinical evaluation of a sustained release compared to a standard formulation of tiaprofenic acid (Surgam) in rheumatoid arthritis: a Canadian multicenter study. Academic Article
Clinical experience with Cerebrolysin® Academic Article
Clinical outcomes with unfractionated heparin or low‐molecular‐weight heparin as bridging therapy in patients on long‐term oral anticoagulants: the REGIMEN registry Academic Article
Clobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of moderate scalp psoriasis Academic Article
Clorgyline-induced switch from locomotion to mouthing in sensitization to the dopamine D2/D3 agonist quinpirole in rats: role of sigma and imidazoline I2 receptors Academic Article
Collaborative Angiographic Patency Trial Of Recombinant Staphylokinase (CAPTORS) Academic Article
Commentary Academic Article
Comparative Efficacies and Tolerabilities of Intravenous Azithromycin Plus Ceftriaxone and Intravenous Levofloxacin with Step-Down Oral Therapy for Hospitalized Patients with Moderate to Severe Community-Acquired Pneumonia Academic Article
Comparative Response in Growth and Bone Status to Three Dexamethasone Treatment Regimens in Infant Piglets Academic Article
Comparative efficacy of long-acting muscarinic antagonist monotherapies in COPD: a systematic review and network meta-analysis Academic Article
Comparison of 1 month with 3 months of anticoagulation for a first episode of venous thromboembolism associated with a transient risk factor Academic Article
Comparison of 5-mg and 10-mg Loading Doses in Initiation of Warfarin Therapy Academic Article
Comparison of Characteristics and Outcomes of Dabigatran Versus Warfarin in Hypertensive Patients With Atrial Fibrillation (from the RE-LY Trial) Academic Article
Comparison of Dabigatran and Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease Academic Article
Comparison of Fixed-Dose Weight-Adjusted Unfractionated Heparin and Low-Molecular-Weight Heparin for Acute Treatment of Venous Thromboembolism Academic Article
Comparison of Low-Intensity Warfarin Therapy with Conventional-Intensity Warfarin Therapy for Long-Term Prevention of Recurrent Venous Thromboembolism Academic Article
Comparison of Low-Molecular-Weight Heparin With Unfractionated Heparin Acutely and With Placebo for 6 Weeks in the Management of Unstable Coronary Artery Disease Academic Article
Comparison of intraoperative fentanyl with dexmedetomidine for perioperative analgesia and opioid consumption during craniotomies: A randomised controlled pilot study with non‐inferiority design Academic Article
Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials Academic Article
Comparison of the effects of gastric antisecretory agents in healthy volunteers and patients with duodenal ulcer. Academic Article
Comparison of the effects of ranitidine, cimetidine and placebo on the 24 hour intragastric acidity and nocturnal acid secretion in patients with duodenal ulcer. Academic Article
Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120 mg, loratadine 10 mg and placebo administered once daily for the treatment of seasonal allergic rhinitis Academic Article
Comparison of three‐factor and four‐factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers Academic Article
Comparison of twice-daily ranitidine with standard cimetidine treatment of duodenal ulcer. Academic Article
Concurrent gemcitabine and radiotherapy with and without neoadjuvant gemcitabine for locally advanced unresectable or resected pancreatic cancer: A phase I-II study Academic Article
Condition-related predictors of successful transition from paediatric to adult care among adolescents with Type 1 diabetes Academic Article
Consistent Management of Repeated Procedural Pain With Sucrose in Preterm Neonates: Is It Effective and Safe for Repeated Use Over Time? Academic Article
Continued vs. interrupted direct oral anticoagulants at the time of device surgery, in patients with moderate to high risk of arterial thrombo-embolic events (BRUISE CONTROL-2) Academic Article
Continuing Outcomes Relevant to Evista: Breast Cancer Incidence in Postmenopausal Osteoporotic Women in a Randomized Trial of Raloxifene Academic Article
Continuous Versus Bolus Infusion of Doxorubicin in Children With ALL: Long-term Cardiac Outcomes Academic Article
Continuous infusion Conference Paper
Continuous infusion of neurotrophin-3 triggers sprouting, decreases the levels of TrkA and TrkC, and inhibits epileptogenesis and activity-dependent axonal growth in adult rats Academic Article
Continuous intravenous infusion of a plasma-derived factor IX concentrate (Mononine^® ) in haemophilia B Academic Article
Continuous varicella-zoster infection associated with acyclovir resistance in a child with AIDS Academic Article
Controlled pilot study of rapid amphotericn B infusions Conference Paper
Controlled trial of clinical utility of serum salicylate monitoring in rheumatoid arthritis. Academic Article
Controversies in timing of the first dose of anticoagulant prophylaxis against venous thromboembolism after major orthopedic surgery. Academic Article
Corticosteroid therapy for acute lung injury, acute respiratory distress syndrome, and severe pneumonia: A meta-analysis of randomized controlled trials Academic Article
Corticosteroid treatment for community-acquired pneumonia - the STEP trial: study protocol for a randomized controlled trial Academic Article
Corticosteroids and neuropsychological functioning in patients with systemic lupus erythematosus Academic Article
Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials Academic Article
Cost-effectiveness analysis of secukinumab for the treatment of active psoriatic arthritis: a Canadian perspective Academic Article
Current approaches to the treatment of advanced-stage Hodgkin's disease. Academic Article
Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial Academic Article
Cyclophosphamide and fluorouracil combined with mitoxantrone versus doxorubicin for breast cancer: superiority of doxorubicin. Academic Article
Cytokine treatment or accessory cells are required to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice Academic Article
DNA damage in rats after treatment with methylphenidate Academic Article
DTIC therapy in metastatic malignant melanoma: a simplified dose schedule. Academic Article
Dabigatran etexilate and reduction in serum apolipoprotein B Academic Article
Dabigatran vs. warfarin in relation to the presence of left ventricular hypertrophy in patients with atrial fibrillation— the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) study Academic Article
Daily Inhaled Corticosteroid Treatment Should Not Be Prescribed for Mild Persistent Asthma Academic Article
Daily Sedation Interruption in Mechanically Ventilated Critically Ill Patients Cared for With a Sedation Protocol Academic Article
Darexaban (YM150) versus enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a randomised phase IIb dose confirmation study (ONYX-3) Academic Article
Delayed but not Early Treatment with DNase Reduces Organ Damage and Improves Outcome in a Murine Model of Sepsis Academic Article
Denosumab Treatment in Postmenopausal Women with Osteoporosis Does Not Interfere with Fracture-Healing Academic Article
Design and baseline characteristics of participants in the R esearching cardiovascular E vents with a W eekly IN cretin in D iabetes ( REWIND ) trial on the cardiovascular effects of dulaglutide Academic Article
Design and baseline results of the monosialoganglioside early stroke trial. The EST Study Group. Academic Article
Design and rationale of CURRENT-OASIS 7: A randomized, 2 × 2 factorial trial evaluating optimal dosing strategies for clopidogrel and aspirin in patients with ST and non–ST-elevation acute coronary syndromes managed with an early invasive strategy Academic Article
Design of the INPULSIS™ trials: Two phase 3 trials of nintedanib in patients with idiopathic pulmonary fibrosis Academic Article
Design, baseline characteristics, and preliminary clinical results of the Organization to Assess Strategies for Ischemic Syndromes–2 (OASIS–2) trial Academic Article
Development and temporal organization of compulsive checking induced by repeated injections of the dopamine agonist quinpirole in an animal model of obsessive-compulsive disorder Academic Article
Development of the IRIS-AR strategy: an intervention to improve rates of accrual and retention for the VTE-PRO randomized controlled trial Academic Article
Differences in the safety profiles of two low-molecular-weight heparins Academic Article
Differential modulation of a 40 kDa catecholamine regulated protein in the core and shell subcompartments of the nucleus accumbens following chronic quinpirole and haloperidol administration in the rat Academic Article
Diltiazem cardioplegia Academic Article
Do corticosteroids reduce the risk of fat embolism syndrome in patients with long-bone fractures? A meta-analysis. Academic Article
Does 3-Day Course of Oral Amoxycillin Benefit Children of Non-Severe Pneumonia with Wheeze: A Multicentric Randomised Controlled Trial Academic Article
Dose Capping Enoxaparin Is Unjustified and Denies Patients With Acute Coronary Syndromes a Potentially Effective Treatment Academic Article
Dose-finding evaluation of once-daily treatment with olodaterol, a novel long-acting β2-agonist, in patients with asthma: results of a parallel-group study and a crossover study Academic Article
Dosing Frequency of Unfractionated Heparin Thromboprophylaxis Academic Article
Double blind placebo controlled trial of short term transdermal scopolamine on heart rate variability in patients with chronic heart failure. Academic Article
Doubling the dose of budesonide versus maintenance treatment in asthma exacerbations Academic Article
Doxorubicin administration by continuous infusion is not cardioprotective: the Dana-Farber 91-01 Acute Lymphoblastic Leukemia protocol. Academic Article
Dual Pathway Inhibition for Vascular Protection in Patients with Atherosclerotic Disease: Rationale and Review of the Evidence Academic Article
Dual-Agent Molecular Targeting of the ErbB2 Receptor: Killing One Bird With Two Stones Academic Article
Duration of Anticoagulant Therapy for Venous Thrombosis Academic Article
Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients* Academic Article
Duration of Initial Empirical Antibiotic Therapy and Outcomes in Very Low Birth Weight Infants Academic Article
Duration of anticoagulant therapy after a first episode of an unprovoked pulmonary embolus or deep vein thrombosis: guidance from the SSC of the ISTH Academic Article
Duration of anticoagulant therapy for deep vein thrombosis and pulmonary embolism Academic Article
Duration of letrozole treatment and outcomes in the placebo-controlled NCIC CTG MA.17 extended adjuvant therapy trial Academic Article
Duvoglustat HCl Increases Systemic and Tissue Exposure of Active Acid α-Glucosidase in Pompe Patients Co-administered with Alglucosidase α Academic Article
EAACI/GA²LEN/EDF/WAO guideline: management of urticaria Academic Article
Editorial Commentary: Short‐Course Treatment of Community‐Acquired Pneumonia Academic Article
Effect of Antenatal Corticosteroids on Fetal Growth and Gestational Age at Birth Academic Article
Effect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism Academic Article
Effect of Everolimus on Bone Marker Levels and Progressive Disease in Bone in BOLERO-2 Academic Article
Effect of Intravenous Iron Sucrose on Exercise Tolerance in Anemic and Nonanemic Patients With Symptomatic Chronic Heart Failure and Iron Deficiency Academic Article
Effect of Prophylactic Indomethacin in Extremely Low Birth Weight Infants Based on the Predicted Risk of Severe Intraventricular Hemorrhage Academic Article
Effect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Failure Academic Article
Effect of a simple two‐step warfarin dosing algorithm on anticoagulant control as measured by time in therapeutic range: a pilot study Academic Article
Effect of a single day of increased as-needed budesonide–formoterol use on short-term risk of severe exacerbations in patients with mild asthma: a post-hoc analysis of the SYGMA 1 study Academic Article
Effect of a thrombopoietin receptor agonist on use of intravenous immune globulin in patients with immune thrombocytopenia Academic Article
Effect of acute antipsychotic administration on dopamine synthesis in rodents and human subjects using 6-[18F]-L-m-tyrosine Academic Article
Effect of baseline CD4 cell count at linkage to HIV care and at initiation of antiretroviral therapy on mortality in HIV-positive adult patients in Rwanda: a nationwide cohort study Academic Article
Effect of extended‐duration thromboprophylaxis on venous thromboembolism and major bleeding among acutely ill hospitalized medical patients: a bivariate analysis Academic Article
Effect of methylprednisolone on acute kidney injury in patients undergoing cardiac surgery with a cardiopulmonary bypass pump: a randomized controlled trial Academic Article
Effect of nafazatrom on platelet function and release: Relationship to symptomatic episodes in patients with peripheral vascular disease Academic Article
Effectiveness and safety of repeat courses of hylan G-F 20 in patients with knee osteoarthritis Academic Article
Effectiveness of desloratadine 5 mg once daily in patients with symptoms of seasonal allergic rhinitis: Results of a Canadian multicenter, open-label trial Academic Article
Effects of 2 years of hormone replacement upon bone mass, serum lipids and lipoproteins Academic Article
Effects of ACE Inhibitors on Mortality When Started in the Early Phase of Myocardial Infarction: Evidence from the Larger Randomized Controlled Trials Academic Article
Effects of Adjuvant Tamoxifen and of Cytotoxic Therapy on Mortality in Early Breast Cancer Academic Article
Effects of Early Intervention With Inhaled Budesonide on Lung Function in Newly Diagnosed Asthma Academic Article
Effects of Glucagon-Like Peptide-1 Receptor Agonists on Weight Loss in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis Academic Article
Effects of a treatment gap during adjuvant chemotherapy in node-positive breast cancer: results of International Breast Cancer Study Group (IBCSG) Trials 13-93 and 14-93 Academic Article
Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study Academic Article
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial Academic Article
Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania Academic Article
Effects of chronic acetazolamide administration on gas exchange and acid-base control in pulmonary circulation in exercising horses Academic Article
Effects of dabigatran according to age in atrial fibrillation Academic Article
Effects of dose and interdose interval on locomotor sensitization to the dopamine agonist quinpirole Academic Article
Effects of inhaled ciclesonide on circulating T-helper type 1/T-helper type 2 cells in atopic asthmatics after allergen challenge Academic Article
Effects of the Once-Weekly Glucagon-Like Peptide-1 Receptor Agonist Dulaglutide on Ambulatory Blood Pressure and Heart Rate in Patients With Type 2 Diabetes Mellitus Academic Article
Efficacy Outcomes in Patients Using Alefacept in the AWARE Study Academic Article
Efficacy and acceptability of nedocromil sodium 2% and olopatadine hydrochloride 0.1% in perennial allergic conjunctivitis Academic Article
Efficacy and safety of a once-yearly i.v. Infusion of zoledronic acid 5 mg versus a once-weekly 70-mg oral alendronate in the treatment of male osteoporosis: A randomized, multicenter, double-blind, active-controlled study Academic Article
Efficacy and safety of a two‐drug direct‐acting antiviral agent regimen ruzasvir 180 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4, 5 or 6 Academic Article
Efficacy and safety of apixaban compared with aspirin in patients who previously tried but failed treatment with vitamin K antagonists: results from the AVERROES trial Academic Article
Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial Academic Article
Efficacy and safety of early parenteral anticoagulation as a bridge to warfarin after mechanical valve replacement Academic Article
Efficacy and safety of fluticasone furoate 100 μg once-daily in patients with persistent asthma: A 24-week placebo and active-controlled randomised trial Academic Article
Efficacy and safety of fondaparinux in major orthopedic surgery according to the timing of its first administration Academic Article
Efficacy and safety of once-daily fluticasone furoate 50 mcg in adults with persistent asthma: a 12-week randomized trial Academic Article
Efficacy and safety of reslizumab in patients with moderate to severe eosinophilic asthma Academic Article
Efficacy and safety of rivaroxaban plus aspirin in women and men with chronic coronary or peripheral artery disease Academic Article
Efficacy and tolerability of fluticasone propionate nasal drops 400 μg once daily compared with placebo for the treatment of bilateral polyposis in adults Academic Article
Efficacy of 5-HT3 Antagonists and 5-HT4 Agonists in Irritable Bowel Syndrome: Systematic Review and Meta-Analysis Academic Article
Efficacy of Gemifloxacin in Acute Exacerbations of Chronic Bronchitis: a Randomised, Double-Blind Comparison with Trovafloxacin Academic Article
Efficacy of a Long-Acting Growth Hormone (GH) Preparation in Patients with Adult GH Deficiency Academic Article
Efficacy of a high purity, chemically treated and nanofiltered factor IX concentrate for continuous infusion in haemophilia patients undergoing surgery Academic Article
Efficacy of progesterone support in the luteal phase following in-vitro fertilization and embryo transfer: meta-analysis of clinical trials Academic Article
Efficiency of aerosol medication delivery from a metered dose inhaler versus jet nebulizer in infants with bronchopulmonary dysplasia Academic Article
Efficient Pharmacokinetic Modeling of Complex Clinical Dosing Regimens: The Universal Elementary Dosing Regimen and Computer Algorithm EDFAST Academic Article
Eight Cycles of ABVD Versus Four Cycles of BEACOPP_escalated Plus Four Cycles of BEACOPP_baseline in Stage III to IV, International Prognostic Score ≥ 3, High-Risk Hodgkin Lymphoma: First Results of the Phase III EORTC 20012 Intergroup Trial Academic Article
Erythropoietin to Prevent Transfusions in Premature Infants Academic Article
Erythropoietin with Iron Supplementation To Prevent Allogeneic Blood Transfusion in Total Hip Joint Arthroplasty Academic Article
Esomeprazole 40 mg and 20 mg is efficacious in the long-term management of patients with endoscopy-negative gastro-oesophageal reflux disease: a placebo-controlled trial of on-demand therapy for 6 months Academic Article
Esomeprazole and aspirin in Barrett's oesophagus (AspECT): a randomised factorial trial Academic Article
Evaluating the Feasibility of Performing Window of Opportunity Trials in Breast Cancer Academic Article
Evaluation of GERD Symptoms during Therapy Academic Article
Evaluation of GERD Symptoms during Therapy Academic Article
Evaluation of fluticasone propionate (500 μg day−1) administered either as dry powder via a Diskhaler® inhaler or pressurized inhaler and compared with beclomethasone dipropionate (1000 μg day−1) administered by pressurized inhaler Academic Article
Evaluation of single-dose inhaled corticosteroid activity with an allergen challenge model☆☆☆★★★ Academic Article
Evidence of astrogliosis in rat hippocampus after d-amphetamine exposure Academic Article
Evidence-Based Management of Anticoagulant Therapy Academic Article
Exacerbations of Asthma Academic Article
Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021 Academic Article
Expanded phase II trial of gemcitabine and capecitabine for advanced biliary cancer Academic Article
Expectations for consultations and antibiotics for respiratory tract infection in primary care: the RTI clinical iceberg Academic Article
Experience with central venous access devices (CVADs) in the Canadian hemophilia primary prophylaxis study (CHPS) Academic Article
Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients Academic Article
Extended duration of thromboprophylaxis in acutely ill medical patients: optimizing therapy? Academic Article
Extended perioperative thromboprophylaxis in patients with cancer. A systematic review. Academic Article
Extended treatment with edoxaban in cancer patients with venous thromboembolism: A post‐hoc analysis of the Hokusai‐VTE Cancer study Academic Article
Extended-Duration Venous Thromboembolism Prophylaxis in Acutely Ill Medical Patients With Recently Reduced Mobility Academic Article
Extending Aromatase-Inhibitor Adjuvant Therapy to 10 Years Academic Article
Failure of montelukast to reduce sputum eosinophilia in high-dose corticosteroid-dependent asthma Academic Article
Fibrinogenolysis and thrombin generation after reduced dose bolus or conventional rt-PA for pulmonary embolism. The Coagulation Project Investigators of the Bolus Alteplase Pulmonary Embolism Group. Academic Article
Five-Day Telithromycin Once Daily Is as Effective as 10-Day Clarithromycin Twice Daily for the Treatment of Acute Exacerbations of Chronic Bronchitis and Is Associated With Reduced Health-Care Resource Utilization Academic Article
Flexibility in Administration of Fondaparinux for Prevention of Symptomatic Venous Thromboembolism in Orthopaedic Surgery Academic Article
Flexibility in starting ovarian stimulation at different phases of the menstrual cycle for treatment of infertile women with the use of in vitro fertilization or intracytoplasmic sperm injection Academic Article
Fluorescence in situ hybridization gene amplification analysis of EGFR and HER2 in patients with malignant salivary gland tumors treated with lapatinib Academic Article
Fluoxetine efficacy in social phobia. Academic Article
Fluoxetine improves functional work capacity in women with premenstrual dysphoric disorder Academic Article
Fluticasone furoate (FF)/vilanterol (100/25 mcg or 200/25 mcg) or FF (100 mcg) in persistent asthma Academic Article
Fluticasone furoate nasal spray reduces symptoms of uncomplicated acute rhinosinusitis: a randomised placebo-controlled study Academic Article
Fluticasone furoate/vilanterol versus fluticasone propionate in patients with asthma and exercise-induced bronchoconstriction Academic Article
Focused 2012 Update of the Canadian Cardiovascular Society Guidelines for the Use of Antiplatelet Therapy Academic Article
Fondaparinux Academic Article
Fondaparinux Compared with Enoxaparin for the Prevention of Venous Thromboembolism after Elective Major Knee Surgery Academic Article
Fondaparinux versus enoxaparin for prevention of venous thromboembolism Academic Article
Fondaparinux: does it cause HIT? can it treat HIT? Academic Article
Formal clinical evaluation of the CADD-Micro system for circadian delivery of FUDR in patients with metastatic renal cell cancer. Academic Article
Fractionated manganese-enhanced MRI Academic Article
Fracture risk in oral glucocorticoid users: a Bayesian meta-regression leveraging control arms of osteoporosis clinical trials Academic Article
Frequency of administration of short half-life nonsteroidal anti-inflammatory analgesics (NSAID's): studies with ibuprofen. Academic Article
Further reductions in nonvertebral fracture rate with long-term denosumab treatment in the FREEDOM open-label extension and influence of hip bone mineral density after 3 years Academic Article
Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty Academic Article
Gatifloxacin used for therapy of outpatient community-acquired pneumonia caused by Streptococcus pneumoniae Academic Article
Gemcitabine concurrent with continuous infusional 5-fluorouracil in advanced biliary cancers: a review of the Princess Margaret Hospital experience Academic Article
Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicentre, double-blind study Academic Article
Gender differences in clinical presentation and response to sertraline treatment of generalized anxiety disorder Academic Article
Genetic biomarkers associated with pain flare and dexamethasone response following palliative radiotherapy in patients with painful bone metastases Academic Article
Goblet Cell Rebound and Airway Dysfunction with Corticosteroid Withdrawal in a Mouse Model of Asthma Academic Article
Graft-versus-host disease following marrow transplantation for aplastic anemia: different impact of two GVHD prevention strategies Academic Article
Granulocyte–macrophage colony‐stimulating factor ( GM ‐ CSF ) as a therapeutic target in psoriasis: randomized, controlled investigation using namilumab, a specific human anti‐ GM ‐ CSF monoclonal antibody Academic Article
Guidelines for antithrombotic therapy: periprocedural management of antithrombotic therapy and use of bridging anticoagulation. Academic Article
Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017 Academic Article
HIT complicating fondaparinux prophylaxis: fondaparinux-dependent platelet activation as a marker for fondaparinux- induced HIT Academic Article
Health-related quality of life of patients with advanced breast cancer treated with everolimus plus exemestane versus placebo plus exemestane in the phase 3, randomized, controlled, BOLERO-2 trial Academic Article
Health-related quality-of-life outcomes of sirolimus-treated kidney transplant patients after elimination of cyclosporine A: results of a 2-year randomized clinical trial1 Conference Paper
Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPI-start' and 'H2-RA-start' management strategies in primary care - the CADET-HR Study Academic Article
Helicobacter pylori infection. Academic Article
Helicobacter pylori infection. Academic Article
Hemorrhagic complications of long-term anticoagulant therapy for ischemic cerebral vascular disease. Academic Article
Heparin and Low-Molecular-Weight Heparin Academic Article
Heparin as an adjunctive treatment after thrombolytic therapy for acute myocardial infarction Academic Article
Heparin for 5 Days as Compared with 10 Days in the Initial Treatment of Proximal Venous Thrombosis Academic Article
High incidence of in-hospital pulmonary embolism following joint arthroplasty with dalteparin prophylaxis Academic Article
High non-compliance in the use of letrozole after 2.5years of extended adjuvant endocrine therapy. Results from the IDEAL randomized trial Academic Article
High-Dose Methotrexate for Gestational Trophoblastic Disease Academic Article
High-Dose Opioid Prescribing and Opioid-Related Hospitalization: A Population-Based Study Academic Article
High-dose cytosine arabinoside in the treatment of preleukemic disorders: A leukemia intergroup study Academic Article
How long should drug treatment of depression last? Academic Article
How much is too much? The treatment of mild asthma Academic Article
How to use unfractionated heparin to treat neonatal thrombosis in clinical practice Academic Article
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII Academic Article
IMPROVEMENT OF MEDICATION COMPLIANCE IN UNCONTROLLED HYPERTENSION Academic Article
Ibandronate for the prevention of nonvertebral fractures: a pooled analysis of individual patient data Academic Article
Ibogaine interferes with motivational and somatic effects of naloxone-precipitated withdrawal from acutely administered morphine Academic Article
Iloprost reduces peripheral resistance during femoro-distal reconstruction Academic Article
Immediate Post–Transurethral Resection of Bladder Tumor Intravesical Chemotherapy Prevents Non–Muscle-invasive Bladder Cancer Recurrences: An Updated Meta-analysis on 2548 Patients and Quality-of-Evidence Review Academic Article
Immunostimulatory Sequences Regulate Interferon-inducible Genes but not Allergic Airway Responses Academic Article
Impact of ABCB1 and CYP2B6 Genetic Polymorphisms on Methadone Metabolism, Dose and Treatment Response in Patients with Opioid Addiction: A Systematic Review and Meta-Analysis Academic Article
Impact of Adopting Population Pharmacokinetics for Tailoring Prophylaxis in Haemophilia A Patients: A Historically Controlled Observational Study Academic Article
Impact of GLP-1 Receptor Agonists on Major Gastrointestinal Disorders for Type 2 Diabetes Mellitus: A Mixed Treatment Comparison Meta-Analysis Academic Article
Impact of Vertebral Fractures and Glucocorticoid Exposure on Height Deficits in Children During Treatment of Leukemia Academic Article
Impact of hormonal treatment duration in combination with radiotherapy for locally advanced prostate cancer: Meta-analysis of randomized trials Academic Article
Impact of premenopausal status at breast cancer diagnosis in women entered on the placebo-controlled NCIC CTG MA17 trial of extended adjuvant letrozole Academic Article
Impaired endothelial antithrombotic activity following short-term interruption of continuous subcutaneous insulin infusion in type1 diabetic patients Academic Article
Implementation of Evidence-Based Practices for Surgical Site Infection Prophylaxis: Results of a Pre- and Postintervention Study Academic Article
Implications of TeqCES: efficacy and safety of gatifloxacin in community-acquired pneumonia Academic Article
Importance of pH Control in the Management of GERD Academic Article
Improving Pain Assessment Practices and Outcomes in Long-Term Care Facilities: A Mixed Methods Investigation Academic Article
Incidence of Cancer after Prophylaxis with Warfarin against Recurrent Venous Thromboembolism Academic Article
Increased Inhaled Bronchodilator vs Increased Inhaled Corticosteroid in the Control of Moderate Asthma Academic Article
Increased Uptake of Guideline-Recommended Oral Antiplatelet Therapy: Insights from the Canadian Acute Coronary Syndrome Reflective Academic Article
Increasing Doses of Inhaled Corticosteroids Compared to Adding Long-Acting Inhaled β 2 -Agonists in Achieving Asthma Control Academic Article
Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials Academic Article
Indacaterol provides sustained 24 h bronchodilation on once-daily dosing in asthma: a 7-day dose-ranging study Academic Article
Individualizing Duration of Dual Antiplatelet Therapy After Acute Coronary Syndrome or Percutaneous Coronary Intervention Academic Article
Influence of preceding length of anticoagulant treatment and initial presentation of venous thromboembolism on risk of recurrence after stopping treatment: analysis of individual participants' data from seven trials Academic Article
Inhaled Combined Budesonide–Formoterol as Needed in Mild Asthma Academic Article
Inhaled Corticosteroids for Asthma: Common Clinical Quandaries Academic Article
Inhaled β₂-Agonists in the Treatment of Asthma Academic Article
Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: results of the PROTECTION AMI Randomized Controlled Trial Academic Article
Initiation, Dose Reduction, and Duration of Inhaled Corticosteroid Therapy Academic Article
Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma Academic Article
Intermittent Androgen Suppression for Rising PSA Level after Radiotherapy Academic Article
Intermittent Cyclic Therapy with Etidronate Prevents Corticosteroid-induced Bone Loss: Two Years of Follow-up Academic Article
Intermittent Etidronate Therapy to Prevent Corticosteroid-Induced Osteoporosis Academic Article
Intermittent androgen deprivation therapy for prostate cancer: translating randomized controlled trials into clinical practice. Academic Article
International Validation of ReQuest™ in Patients with Endoscopy-Negative Gastro-Oesophageal Reflux Disease Academic Article
Interruptions During the Delivery of High-Risk Medications Academic Article
Interventions to Enhance Medication Adherence in Chronic Medical Conditions Academic Article
Intraperitoneal Calcitriol for Treatment of Severe Hyperparathyroidism in Children with Chronic Kidney Disease: A Therapy Forgotten Academic Article
Is Impaired Renal Function a Contraindication to the Use of Low-Molecular-Weight Heparin? Academic Article
Is maternal use of selective serotonin reuptake inhibitors in the third trimester of pregnancy harmful to neonates? Academic Article
Is the Routine Use of Inhaled β-Adrenergic Agonists Appropriate in Asthma Treatment?: No Academic Article
Isotonic versus hypotonic fluid supplementation in term neonates with severe hyperbilirubinemia - a double-blind, randomized, controlled trial Academic Article
Ketamine concentrations during cardiopulmonary bypass Academic Article
Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats Academic Article
Lack of effect of antipsychotics on BNDF and NGF levels in hippocampus of Wistar rats Academic Article
Lapatinib or Trastuzumab Plus Taxane Therapy for Human Epidermal Growth Factor Receptor 2–Positive Advanced Breast Cancer: Final Results of NCIC CTG MA.31 Academic Article
Late Extended Adjuvant Treatment With Letrozole Improves Outcome in Women With Early-Stage Breast Cancer Who Complete 5 Years of Tamoxifen Academic Article
Lidocaine Therapy with an Exponentially Declining Infusion Academic Article
Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure: Primary Results of the ENABLE Trials Academic Article
Long-Term Follow-Up of Women in Trials of Adjuvant Therapy for Breast Cancer: Is It Still Important? Academic Article
Long-term amiodarone therapy and the risk of complications after cardiac surgery: Results from the Canadian Amiodarone Myocardial Infarction Arrhythmia Trial (CAMIAT) Academic Article
Long-term interferon-β treatment for multiple sclerosis Academic Article
Long-term outcome of a pediatric-inspired regimen used for adults aged 18–50 years with newly diagnosed acute lymphoblastic leukemia Academic Article
Long-term risk of recurrence after discontinuing anticoagulants for a first unprovoked venous thromboembolism: protocol for a systematic review and meta-analysis Academic Article
Long-term safety and efficacy of omeprazole in gastro-oesophageal reflux disease Academic Article
Longer- Versus Shorter-Duration Dual-Antiplatelet Therapy After Drug-Eluting Stent Placement Academic Article
Longitudinal Assessment of Growth, Mineral Metabolism, and Bone Mass in Pediatric Crohnʼs Disease Academic Article
Long‐term risk of recurrence in patients with a first unprovoked venous thromboembolism managed according to d‐dimer results; A cohort study Academic Article
Lorazepam treatment of acute and chronic catatonia in two mentally retarded brothers. Academic Article
Low Adherence to Recommended Guidelines for Open Fracture Antibiotic Prophylaxis Academic Article
Low Molecular Weight Heparin Administered once versus twice Daily in Patients with Venous Thromboembolism Academic Article
Low molecular weight heparin: laboratory properties and clinical evaluation. A review. Academic Article
Low-Molecular-Weight Heparin vs. Warfarin for Prophylaxis against Deep-Vein Thrombosis Academic Article
Low-Molecular-Weight Heparins in the Treatment of Acute Coronary Syndromes Academic Article
Low-dose Aspirin and Cancer Mortality: A Meta-analysis of Randomized Trials Academic Article
Low-dose cyclosporin versus placebo in patients with rheumatoid arthritis Academic Article
Low-dose dexamethasone challenge in women with atypical major depression: pilot study. Academic Article
Luteal Phase Administration of Paroxetine for the Treatment of Premenstrual Dysphoric Disorder Academic Article
Luteal Phase and Symptom-Onset Dosing of SSRIs/SNRIs in the Treatment of Premenstrual Dysphoria: Clinical Evidence and Rationale Academic Article
Maintenance of asthma control by once-daily inhaled ciclesonide in adults with persistent asthma Academic Article
Major bleeding risk with warfarin for deep vein thrombosis. Academic Article
Management Of Venous Thromboembolism: Optimization By Clinical Trials Academic Article
Management of Complicated Urinary Tract Infections in the Era of Antimicrobial Resistance Academic Article
Maternal vitamin D supplementation during pregnancy and lactation to promote infant growth in Dhaka, Bangladesh (MDIG trial): study protocol for a randomized controlled trial Academic Article
Methemoglobinemia in children with acute lymphoblastic leukemia (ALL) receiving dapsone forpneumocystis carinii pneumonia (PCP) prophylaxis: A correlation with cytochrome b5 reductase (Cb5R) enzyme levels Academic Article
Methotrexate/fluorouracil scheduling influences normal tissue toxicity but not antitumor effects in patients with squamous cell head and neck cancer: results from a randomized trial. Academic Article
Missing Anticitrullinated Protein Antibody Does Not Affect Short-term Outcomes in Early Inflammatory Arthritis: From the Canadian Early Arthritis Cohort Academic Article
Mitigating errors caused by interruptions during medication verification and administration: interventions in a simulated ambulatory chemotherapy setting Academic Article
Modulatory effects of estrogen in two murine models of experimental colitis Academic Article
Multicenter randomized controlled trial comparing different schedules of somatostatin in the treatment of acute variceal bleeding Academic Article
Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study: 2-Year Outcomes Academic Article
Multiple courses of antenatal corticosteroids for preterm birth (MACS): a randomised controlled trial Academic Article
Multiple daily doses of acetyl‐salicylic acid (ASA) overcome reduced platelet response to once‐daily ASA after coronary artery bypass graft surgery: a pilot randomized controlled trial Academic Article
Musculoskeletal health of subjects with hemophilia A treated with tailored prophylaxis: Canadian Hemophilia Primary Prophylaxis (CHPS) Study Academic Article
Myostatin inhibitor ACE-031 treatment of ambulatory boys with Duchenne muscular dystrophy: Results of a randomized, placebo-controlled clinical trial Academic Article
N of 1 randomized trials for investigating new drugs Academic Article
Nanoparticle albumin-bound paclitaxel for second-line treatment of metastatic urothelial carcinoma: a single group, multicentre, phase 2 study Academic Article
Nefazodone in Social Phobia Academic Article
New Anticoagulants for Treatment of Venous Thromboembolism Academic Article
New Antithrombotic Drugs: Potential for Use in Oncology Academic Article
New onset vasomotor symptoms but not musculoskeletal symptoms associate with clinical outcomes on extended adjuvant letrozole – Analyses from NCIC CTG MA.17 Academic Article
New oral anticoagulants in elderly patients Academic Article
New oral anticoagulants: not quite there yet Academic Article
Omeprazole (20 mg daily) versus cimetidine (1200 mg daily) in duodenal ulcer healing and pain relief Academic Article
On-demand vs. prophylactic treatment for severe haemophilia in Norway and Sweden: differences in treatment characteristics and outcome Academic Article
Once Daily Dosing Improves Adherence to Antiretroviral Therapy Academic Article
Once versus twice daily aspirin after coronary bypass surgery: a randomized trial Academic Article
Once-Daily Administration of Budesonide Turbuhaler® was as Effective as Twice-Daily Treatment in Patients with Mild to Moderate Persistent Asthma Academic Article
Once-Daily Aminoglycoside Dosing in Immunocompetent Adults Academic Article
Once-Daily Dosing vs. Conventional Dosing Schedule of Mesalamine and Relapse of Quiescent Ulcerative Colitis: Systematic Review and Meta-Analysis Academic Article
Once-Daily Therapy with Ceftriaxone Compared with Daily Multiple-Dose Therapy with Cefotaxime for Serious Bacterial Infections: A Randomized, Double-Blind Study Academic Article
Once-Yearly Zoledronic Acid in Older Men Compared with Women with Recent Hip Fracture Academic Article
Once-daily ciclesonide 80 or 320μg for 12 weeks is safe and effective in patients with persistent asthma Academic Article
Once-daily fluticasone furoate alone or combined with vilanterol in persistent asthma Academic Article
Once‐daily fluticasone furoate 50 mcg in mild‐to‐moderate asthma: a 24‐week placebo‐controlled randomized trial Academic Article
One Year of Romosozumab Followed by Two Years of Denosumab Maintains Fracture Risk Reductions: Results of the FRAME Extension Study Academic Article
Onset of Response with Duloxetine Treatment in Patients with Osteoarthritis Knee Pain and Chronic Low Back Pain: A Post Hoc Analysis of Placebo-Controlled Trials Academic Article
Optimal Duration of Anticoagulant Therapy Academic Article
Optimal Duration of Oral Anticoagulant Therapy: A Randomized Trial Comparing Four Weeks with Three Months of Warfarin in Patients with Proximal Deep Vein Thrombosis Academic Article
Optimal intervention time and risk of the activating blood and removing stasis method in acute cerebral hemorrhage patients Academic Article
Optimal management of metastatic bone disease Academic Article
Optimal timing for antiretroviral therapy initiation in patients with HIV infection and concurrent cryptococcal meningitis Academic Article
Optimal timing of vitamin K antagonist resumption after upper gastrointestinal bleeding Academic Article
Optimizing gentamicin conventional and extended interval dosing in neonates using Monte Carlo simulation – a retrospective study Academic Article
Optimum Use of Anticoagulants in Pregnancy Academic Article
Optimum duration of regimens forHelicobacter pylorieradication Academic Article
Oral anticoagulant re-initiation following intracerebral hemorrhage in non-valvular atrial fibrillation: Global survey of the practices of neurologists, neurosurgeons and thrombosis experts Academic Article
Oral anticoagulation in venous thromboembolism: decisions based on more than mere feelings Academic Article
Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement Academic Article
Oral rivaroxaban for the prevention of symptomatic venous thromboembolism after elective hip and knee replacement Academic Article
Osteopenia in children with acute lymphoblastic leukemia: A pilot study of amelioration with pamidronate Academic Article
Outcomes in patients with advanced urothelial carcinoma after discontinuation of programmed death (PD)-1 or PD ligand 1 inhibitor therapy Academic Article
Overview of the New Oral Anticoagulants Academic Article
PAOPA, a potent analogue of Pro-Leu-glycinamide and allosteric modulator of the dopamine D2 receptor, prevents NMDA receptor antagonist (MK-801)-induced deficits in social interaction in the rat: Implications for the treatment of negative symptoms in schizophrenia Academic Article
PaTH Forward: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of TransCon PTH in Adult Hypoparathyroidism Academic Article
Pantoprazole to Prevent Gastroduodenal Events in Patients Receiving Rivaroxaban and/or Aspirin in a Randomized, Double-Blind, Placebo-Controlled Trial Academic Article
Paper-based dosing algorithms for maintenance of warfarin anticoagulation Academic Article
Paroxetine Controlled Release for Premenstrual Dysphoric Disorder: A Double-Blind, Placebo-Controlled Trial Academic Article
Paroxetine in Social Phobia Academic Article
Pediatric Cellulitis Academic Article
Peginterferon alpha-2a versus peginterferon alpha-2b for chronic hepatitis C Academic Article
Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial Academic Article
Perioperative Antibiotic Prophylaxis in Total Joint Arthroplasty Academic Article
Perioperative Aspirin and Clonidine and Risk of Acute Kidney Injury Academic Article
Perioperative Corticosteroids Reduce Short-Term Edema and Ecchymosis in Rhinoplasty: A Meta-Analysis Academic Article
Perioperative Management of Antithrombotic Therapy Academic Article
Perioperative Management of Oral Anticoagulation Academic Article
Perioperative bridging anticoagulation during dabigatran or warfarin interruption among patients who had an elective surgery or procedure Academic Article
Periprocedural interruption of anticoagulation in patients with cancer‐associated venous thromboembolism: An analysis of thrombotic and bleeding outcomes Academic Article
Persistence With Dabigatran Therapy at 2 Years in Patients With Atrial Fibrillation Academic Article
Persistence at 12 months with denosumab in postmenopausal women with osteoporosis: interim results from a prospective observational study Academic Article
Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis Academic Article
Pharmacokinetic Optimisation of the Treatment of Deep Vein Thrombosis Academic Article
Pharmacokinetic Studies of Single and Multiple Oral Doses of Fampridine-SR (Sustained-Release 4-Aminopyridine) in Patients With Chronic Spinal Cord Injury Academic Article
Pharmacokinetics, Safety, and Efficacy of Trastuzumab Administered Every Three Weeks in Combination With Paclitaxel Academic Article
Phase 2 study of TAK-442, an oral factor Xa inhibitor, in patients following acute coronary syndrome Academic Article
Phase I Trial of the Matrix Metalloproteinase Inhibitor Marimastat Combined with Carboplatin and Paclitaxel in Patients with Advanced Non–Small Cell Lung Cancer Academic Article
Phase I clinical, pharmacokinetic and pharmacodynamic study of SB939, an oral histone deacetylase (HDAC) inhibitor, in patients with advanced solid tumours Academic Article
Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors Academic Article
Phase I/II Trial of Metronomic Chemotherapy With Daily Dalteparin and Cyclophosphamide, Twice-Weekly Methotrexate, and Daily Prednisone As Therapy for Metastatic Breast Cancer Using Vascular Endothelial Growth Factor and Soluble Vascular Endothelial Growth Factor Receptor Levels As Markers of Response Academic Article
Phase II Study of Pemetrexed With and Without Folic Acid and Vitamin B₁₂ as Front-Line Therapy in Malignant Pleural Mesothelioma Academic Article
Phase II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in combination with rituximab in patients with recurrent B-cell non-Hodgkin lymphoma Academic Article
Phase II study of CGP 69846A (ISIS 5132) in recurrent epithelial ovarian cancer: an NCIC clinical trials group study (NCIC IND.116)☆ Academic Article
Phase II study of oral menogaril as first line chemotherapy for advanced breast cancer: A National Cancer Institute of Canada Clinical Trials Group Study Academic Article
Phase II study of weekly edatrexate as first-line chemotherapy for metastatic breast cancer: a National Cancer Institute of Canada Clinical Trials Group study. Academic Article
Phase III Comparative Study of Vinorelbine Combined With Doxorubicin Versus Doxorubicin Alone in Disseminated Metastatic/Recurrent Breast Cancer: National Cancer Institute of Canada Clinical Trials Group Study MA8 Academic Article
Phase III Study of Pemetrexed in Combination With Cisplatin Versus Cisplatin Alone in Patients With Malignant Pleural Mesothelioma Academic Article
Polychemotherapy for early breast cancer: an overview of the randomised trials Academic Article
Postnatal pulmonary distension for the treatment of pulmonary hypoplasia: pilot study in the neonatal piglet model Conference Paper
Practical guidance for using rivaroxaban in patients with atrial fibrillation: balancing benefit and risk Academic Article
Practice guideline for the role of combination chemotherapy in the initial management of limited-stage small-cell lung cancer Academic Article
Pre-prandial vs. post-prandial capillary glucose measurements as targets for repaglinide dose titration in people with diet-treated or metformin-treated Type 2 diabetes: a randomized controlled clinical trial Academic Article
Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH) Academic Article
Prediction of Area under the Cyclosporine Concentration Versus Time Curve in Children Undergoing Hematopoietic Stem Cell Transplantation Academic Article
Predictors of Loss of Asthma Control Induced by Corticosteroid Withdrawal Academic Article
Predictors of Prolonged Opioid Use After Initial Prescription for Acute Musculoskeletal Injuries in Adults Academic Article
Pregabalin reduces postoperative opioid consumption and pain for 1 week after hospital discharge, but does not affect function at 6 weeks or 3 months after total hip arthroplasty Academic Article
Preliminary evaluation of oral anticonvulsant treatment in the quinpirole model of bipolar disorder Academic Article
Presence and bioavailability of bisphenol A in the uterus of rats and mice following single and repeated dietary administration at low doses Academic Article
Prevention of Arrhythmia Device Infection Trial Academic Article
Prevention of Deep Vein Thrombosis after Elective Hip Surgery Academic Article
Prevention of Infections in Cardiac Surgery study (PICS): study protocol for a pragmatic cluster-randomized factorial crossover pilot trial Academic Article
Prevention of VTE in Orthopedic Surgery Patients Academic Article
Prevention of left ventricular mural thrombus Academic Article
Procalcitonin-guided antibiotic therapy algorithms for different types of acute respiratory infections based on previous trials Academic Article
Procedural pain in newborns at risk for neurologic impairment Academic Article
Programming effects in sheep of prenatal growth restriction and glucocorticoid exposure Academic Article
Progression through diabetes therapies among new elderly users of metformin: a population-based study Academic Article
Prolonged Antithrombin Activity of Low-Molecular-Weight Heparins Academic Article
Prospective randomized trial of one-hour sequential versus simultaneous methotrexate plus 5-fluorouracil in advanced and recurrent squamous cell head and neck cancer. Academic Article
Proteasome Inhibition With Bortezomib (PS-341): A Phase I Study With Pharmacodynamic End Points Using a Day 1 and Day 4 Schedule in a 14-Day Cycle Academic Article
Protocols for the Use of Cyproterone, Medroxyprogesterone, and Leuprolide in the Treatment of Paraphilia Academic Article
Protracted akathisia after risperidone withdrawal Academic Article
Psychopharmacologic treatment of pediatric major depressive disorder Academic Article
Quality of life in stage II breast cancer: an instrument for clinical trials. Academic Article
Quetiapine augmentation of SRIs in treatment refractory obsessive-compulsive disorder: a double-blind, randomised, placebo-controlled study [ISRCTN83050762] Academic Article
RANITIDINE 150 mg TWICE DAILY VS 300 mg NIGHTLY IN TREATMENT OF DUODENAL ULCERS Academic Article
RUDER: interim evaluation of a 2-year, multicentre study of risk factors for duodenal ulcer relapse. Academic Article
Randomised study ofefficacy of Omeprazole and clarithromycin with either amoxycillin or metronidazole in the eradication of Helicobacter pylori in screened primary care patients Academic Article
Randomised, double-blind trial of carboplatin and paclitaxel with daily oral cediranib or placebo in patients with advanced non-small cell lung cancer: NCIC Clinical Trials Group study BR29 Academic Article
Randomized Controlled Trial of 7-Day vs. 14-Day Antibiotics for Neonatal Sepsis Academic Article
Randomized Phase III Study of Fludarabine Phosphate Versus Cyclophosphamide, Vincristine, and Prednisone in Patients With Recurrent Low-Grade Non-Hodgkin’s Lymphoma Previously Treated With an Alkylating Agent or Alkylator-Containing Regimen Academic Article
Randomized phase II comparison of standard CHOP with weekly CHOP in elderly patients with non-Hodgkin's lymphoma. Academic Article
Randomized trial of candesartan cilexetil in the treatment of patients with congestive heart failure and a history of intolerance to angiotensin-converting enzyme inhibitors Academic Article
Randomized, Double-Blinded, Placebo-Controlled, Trial of Risedronate for the Prevention of Bone Mineral Density Loss in Nonmetastatic Prostate Cancer Patients Receiving Radiation Therapy Plus Androgen Deprivation Therapy Academic Article
Rapid quantitative D‐dimer to exclude pulmonary embolism: a prospective cohort management study Academic Article
Rational use of oral bisphosphonates for the treatment of osteoporosis Academic Article
Rationale and design of AVERROES: Apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K antagonist treatment Academic Article
Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: The BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT) Academic Article
Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention) Academic Article
Re: Cost-Effectiveness of Aspirin Chemoprevention for Barrett's Esophagus Academic Article
Reaching recommended lipid and blood pressure targets with amlodipine/atorvastatin combination in patients with coronary heart disease Academic Article
Reactivation of coagulation after stopping infusions of recombinant hirudin and unfractionated heparin in unstable angina and myocardial infarction without ST elevation: results of a randomized trial Academic Article
Real-life treatment of venous thromboembolism with direct oral anticoagulants: The influence of recommended dosing and regimens Academic Article
Recurrent Venous Thrombosis and Heparin Therapy Academic Article
Reduced‐dose direct oral anticoagulants in the extended treatment of venous thromboembolism: a systematic review and meta‐analysis Academic Article
Regular inhaled beta-agonist treatment in bronchial asthma Academic Article
Regular versus as-needed inhaled salbutamol in asthma control Academic Article
Relationship between quality of life and clinical status in asthma: a factor analysis Academic Article
Repeated Doses of Porcine Secretin in the Treatment of Autism: A Randomized, Placebo-Controlled Trial Academic Article
Residual Vein Thrombosis and D-Dimer for Optimizing Duration of Anticoagulation in Idiopathic Deep Vein Thrombosis Academic Article
Residual Venous Obstruction, alone and in Combination with D-Dimer, as a Risk Factor for Recurrence after Anticoagulation Withdrawal following a First Idiopathic Deep Vein Thrombosis in the Prolong Study Academic Article
Residual vein thrombosis for assessing duration of anticoagulation after unprovoked deep vein thrombosis of the lower limbs: The extended DACUS study Academic Article
Restart of Anticoagulant Therapy and Risk of Thrombosis, Rebleeding, and Death after Factor Xa Inhibitor Reversal in Major Bleeding Patients Academic Article
Reversal of the anti‐platelet effects of aspirin and clopidogrel Academic Article
Risk of Bleeding With 2 Doses of Dabigatran Compared With Warfarin in Older and Younger Patients With Atrial Fibrillation Academic Article
Risk of recurrent venous thromboembolism according to baseline risk factor profiles Academic Article
Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness Academic Article
Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism Academic Article
Rivaroxaban versus enoxaparin after total knee arthroplasty Academic Article
Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial Academic Article
Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial Academic Article
Role of aspirin for prevention and treatment of perioperative cardiovascular events Academic Article
Role of quinolones in surgical prophylaxis Academic Article
Romosozumab in Skeletally Mature Adults with a Fresh Unilateral Tibial Diaphyseal Fracture Academic Article
Safety and Efficacy of Low Blood Pressures Among Patients With Diabetes Academic Article
Safety and Tolerability of North American Ginseng Extract in the Treatment of Pediatric Upper Respiratory Tract Infection: A Phase II Randomized, Controlled Trial of 2 Dosing Schedules Academic Article
Safety and efficacy of gatifloxacin in community-acquired pneumonia: rationale for the Tequin Clinical Experience Study (TeqCES) Conference Paper
Safety and physiological effects of two different doses of elosulfase alfa in patients with morquio a syndrome: A randomized, double-blind, pilot study Academic Article
Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the β₂agonist vilanterol administered once daily for 52 weeks in patients ≥12 years old with asthma: a randomised trial Academic Article
Safety of Long-Acting β-Agonists Academic Article
Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin Academic Article
Safety of Uninterrupted Anticoagulation in Patients Requiring Elective Coronary Angiography With or Without Percutaneous Coronary Intervention Academic Article
Scientific and Standardization Committee Communication: Guidance document on the periprocedural management of patients on chronic oral anticoagulant therapy: Recommendations for standardized reporting of procedural/surgical bleed risk and patient‐specific thromboembolic risk Academic Article
Scientific and Standardization Committee communication: Clinical guidance on the diagnosis, prevention, and treatment of venous thromboembolism in hospitalized patients with COVID‐19 Academic Article
Second-line or Subsequent Systemic Therapy for Recurrent or Progressive Non-Small Cell Lung Cancer: A Systematic Review and Practice Guideline Academic Article
Secukinumab administration by pre-filled syringe: efficacy, safety and usability results from a randomized controlled trial in psoriasis (FEATURE) Academic Article
Sedation and Analgesia in Adult Patients: Evaluation of a Staged-Dose System Based on Body Weight for Use in Abdominal Interventional Radiology Academic Article
Sekundärprävention nach ischämischem zerebralem Insult Academic Article
Selective thrombocytopenia in children with Wilms tumor: An immune-mediated effect of dactinomycin? Academic Article
Selexipag for the Treatment of Pulmonary Arterial Hypertension Academic Article
Semuloparin for prevention of venous thromboembolism after major orthopedic surgery: results from three randomized clinical trials, SAVE‐HIP1, SAVE‐HIP2 and SAVE‐KNEE Academic Article
Serotonin Agents in the Treatment of Acquired Brain Injury Academic Article
Serum Lipoprotein (a) Levels in Patients with First Unprovoked Venous Thromboembolism is not Associated with Subsequent Risk of Recurrent VTE Academic Article
Short course versus 7-day course of intravenous antibiotics for probable neonatal septicemia: A pilot, open-label, randomized controlled trial Academic Article
Short-Duration Prophylaxis Against Venous Thromboembolism After Total Hip or Knee Replacement Academic Article
Short-acting inhaled β-agonists: to be taken regularly or as needed? Academic Article
Short-course antimicrobial therapy for paediatric respiratory infections (SAFER): study protocol for a randomized controlled trial Academic Article
Short-term dabigatran interruption before cardiac rhythm device implantation: multi-centre experience from the RE-LY trial Academic Article
Should Aspirin Be Discontinued Before Coronary Artery Bypass Surgery? Academic Article
Should Remdesivir Be Used for the Treatment of Patients With COVID-19? Rapid, Living Practice Points From the American College of Physicians (Version 1) Academic Article
Should Supplemental Antioxidant Administration Be Avoided During Chemotherapy and Radiation Therapy? Academic Article
Should patients with cardiovascular disease take fish oil? Academic Article
Should patients with stable coronary artery disease be treated with ACE inhibitor therapy? Academic Article
Single Daily Dosing of Aminoglycosides in Immunocompromised Adults: A Systematic Review Academic Article
Single and repeated ketamine infusions for reduction of suicidal ideation in treatment-resistant depression Academic Article
Single versus multiple courses of antenatal betamethasone and neonatal outcome: a randomized controlled trial. Academic Article
Single-center experience with botulinum toxin endoscopic detrusor injection for the treatment of congenital neuropathic bladder in children: Effect of dose adjustment, multiple injections, and avoidance of reconstructive procedures Academic Article
Single-dose adjustment versus no adjustment of warfarin in stably anticoagulated patients with an occasional international normalized ratio (INR) out of range Academic Article
Sirolimus Therapy after Early Cyclosporine Withdrawal Reduces the Risk for Cancer in Adult Renal Transplantation Academic Article
Skeletal findings in children recently initiating glucocorticoids for the treatment of nephrotic syndrome Academic Article
Smoking as a risk factor for duodenal ulcer relapse. RUDER Study Group. Academic Article
SodiUm SeleniTe Adminstration IN Cardiac Surgery (SUSTAIN CSX-trial): study design of an international multicenter randomized double-blinded controlled trial of high dose sodium-selenite administration in high-risk cardiac surgical patients Academic Article
Some features of miocamycin in the gynecological field: pharmacokinetic data using preoperative administration and therapeutic aspects against chlamydial infections. Academic Article
Statins for acute coronary syndrome Academic Article
Statins for acute coronary syndrome Academic Article
Steady-state plasma levels of salicylate in patients with rheumatoid arthritis: effects of dosing interval and tablet strength. Academic Article
Strategic use of new generation antidepressants for depression: SUN(^_^) D protocol update and statistical analysis plan Academic Article
Stroke Prevention in Atrial Fibrillation Academic Article
Subtherapeutic Posaconazole Exposure and Treatment Outcome in Patients With Invasive Fungal Disease Academic Article
Successful Management of Intractable Nausea with Ondansetron: A Case Study Academic Article
Superiority of Alternating Non-Cross-Resistant Chemotherapy in Extensive Small Cell Lung Cancer Academic Article
Survival and PSA response of patients in the TAX 327 study who crossed over to receive docetaxel after mitoxantrone or vice versa Academic Article
Survival with Tiotropium Compared to Long-Acting Beta-2-Agonists in Chronic Obstructive Pulmonary Disease Academic Article
Symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD): a case series Academic Article
Systematic Review: d-Dimer to Predict Recurrent Disease after Stopping Anticoagulant Therapy for Unprovoked Venous Thromboembolism Academic Article
Systematic Review: Efficacy and Safety of Rituximab for Adults with Idiopathic Thrombocytopenic Purpura Academic Article
Systematic review of the effect of denosumab on children with osteogenesis imperfecta showed inconsistent findings Academic Article
Systemic Effect Comparisons of Six Inhaled Corticosteroid Preparations Academic Article
THE CANADIAN AMERICAN TICLOPIDINE STUDY (CATS) IN THROMBOEMBOLIC STROKE Academic Article
TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway Academic Article
Tailored frequency-escalated primary prophylaxis for severe haemophilia A: results of the 16-year Canadian Hemophilia Prophylaxis Study longitudinal cohort Academic Article
Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study Academic Article
Tailoring warfarin induction doses to reflect individual and disease-specific factors Academic Article
Take as Directed Academic Article
Temozolomide in metastatic breast cancer (MBC): a phase II trial of the National Cancer Institute of Canada – Clinical Trials Group (NCIC-CTG) Academic Article
The 2004 Canadian recommendations for the management of hypertension: Part II--Therapy. Academic Article
The ARIA/EAACI criteria for antihistamines: an assessment of the efficacy, safety and pharmacology of desloratadine Academic Article
The BENEFIT trial: testing the hypothesis that trypanocidal therapy is beneficial for patients with chronic Chagas heart disease Academic Article
The Canadian Experience with Intensive Fluorouracil, Epirubicin and Cyclophosphamide in Patients with Early Stage Breast Cancer Academic Article
The Correlation between Acid Suppression and Peptic Ulcer Healing Academic Article
The Effects of Steroids on Coagulation Dysfunction Induced by Cardiopulmonary Bypass: A Steroids in Cardiac Surgery (SIRS) Trial Substudy Academic Article
The Efficacy and Tolerability of Risedronate Once a week for the Treatment of Postmenopausal Osteoporosis Academic Article
The Incidence of Symptomatic Venous Thromboembolism During and After Prophylaxis With Enoxaparin<subtitle>A Multi-institutional Cohort Study of Patients Who Underwent Hip or Knee Arthroplasty</subtitle> Conference Paper
The MARINER trial of rivaroxaban after hospital discharge for medical patients at high risk of VTE Academic Article
The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations Academic Article
The Optimal Duration of Anticoagulant Therapy for Venous Thrombosis Academic Article
The Pharmacology and Management of the Vitamin K Antagonists Academic Article
The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review Academic Article
The Selective GABA Reuptake Inhibitor Tiagabine for the Treatment of Generalized Anxiety Disorder Academic Article
The Thrombogenic Effect of Anticancer Drug Therapy in Women with Stage II Breast Cancer Academic Article
The Toronto Consensus for the Treatment of Helicobacter pylori Infection in Adults Academic Article
The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial Academic Article
The clinical relevance of pharmacological blood pressure lowering mechanisms. Academic Article
The effect of increasing doses of β-agonists on airflow in patients with chronic airflow limitation Academic Article
The effect of low-dose colchicine in patients with stable coronary artery disease: The LoDoCo2 trial rationale, design, and baseline characteristics Academic Article
The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction Academic Article
The effect of routine vs. p.r.n. post-operative analgesia on pulmonary complications: a multicenter trial. Academic Article
The effect of the duration of anticoagulation and other risk factors on the recurrence of venous thromboembolisms. Duration of Anticoagulation Study Group. Academic Article
The effectiveness of aerobic and muscle strength training in patients receiving hemodialysis and EPO: A randomized controlled trial Academic Article
The effects of timing of prophylaxis, type of anesthesia, and use of mechanical methods on outcome in major orthopedic surgery - subgroup analyses from 17,701 patients in the XAMOS study Academic Article
The efficacy and safety of sunitinib given on an individualised schedule as first-line therapy for metastatic renal cell carcinoma: A phase 2 clinical trial Academic Article
The evolution of β2-agonists Academic Article
The impact of GI events on persistence and adherence to osteoporosis treatment: 3-, 6-, and 12-month findings in the MUSIC-OS study Academic Article
The optimal intensity of oral anticoagulant therapy Academic Article
The organization to assess strategies for ischemic syndromes (OASIS) pilot study: evaluation of acute and long-term therapies for patients with acute coronary syndromes without ST elevation Academic Article
The significance of hypofibrinolysis for the risk of recurrence of venous thromboembolism. Duration of Anticoagulation (DURAC) Trial Study Group. Academic Article
The time to and determinants of first fractures in boys with Duchenne muscular dystrophy Academic Article
The use of multiple respiratory inhalers requiring different inhalation techniques has an adverse effect on COPD outcomes Academic Article
The use of prophylaxis in 2663 children and adults with haemophilia: results of the 2006 Canadian national haemophilia prophylaxis survey Academic Article
The “parallel-cohort RCT”: Novel design aspects and application in the Kids-DOTT trial of pediatric venous thromboembolism Academic Article
Theoretical and Practical Aspects of Thrombolytic Therapy Academic Article
Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial Academic Article
Three-month efficacy and safety of once-daily diltiazem in chronic stable angina pectoris Academic Article
Thrombin generation after the abrupt cessation of intravenous unfractionated heparin among patients with acute coronary syndromes Academic Article
Thromboembolic events, recurrent bleeding and mortality after resuming anticoagulant following gastrointestinal bleeding Academic Article
Time to maximum effect of lansoprazole on gastric pH in normal male volunteers Academic Article
Timing is everything: Targeting IgE to reduce asthma exacerbation risk Academic Article
Timing of CMF chemotherapy in combination with tamoxifen in postmenopausal women with breast cancer: role of endocrine responsiveness of the tumor Academic Article
Timing of initiation of antiretroviral therapy and adverse pregnancy outcomes: a systematic review and meta-analysis Academic Article
Timing the First Postoperative Dose of Anticoagulants Academic Article
Tirapazamine with cisplatin in patients with advanced non-small-cell lung cancer: a phase II study. Academic Article
To the editor: Are long‐acting beta‐agonists the “winning team” in childhood asthma? Academic Article
Tolerability and efficacy of docetaxel in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial Academic Article
Topiramate Treatment for SSRI-Induced Weight Gain in Anxiety Disorders Academic Article
Transient Corticosteroid Treatment Permanently Amplifies the Th2 Response in a Murine Model of Asthma Academic Article
Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline Academic Article
Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis Academic Article
Treatment of Venous Thromboembolism Academic Article
Treatment of advanced Hodgkin's disease with chemotherapy--comparison of MOPP/ABV hybrid regimen with alternating courses of MOPP and ABVD: a report from the National Cancer Institute of Canada clinical trials group. Academic Article
Treatment of premenstrual dysphoria with selective serotonin re-uptake inhibitors: focus on safety Academic Article
Treatment of proximal vein thrombosis with subcutaneous low-molecular-weight heparin vs intravenous heparin. An economic perspective Academic Article
Treatment of venous thromboembolic disease. Academic Article
Treatment of venous thromboembolism in cancer patients with dalteparin for up to 12 months: the DALTECAN Study Academic Article
Trends in selection and timing of first‐line pharmacotherapy in older patients with Type 2 diabetes diagnosed between 1994 and 2006 Academic Article
Twice-daily and once-daily nedocromil sodium 2% ophthalmic solution for the treatment of seasonal allergic conjunctivitis Academic Article
Two doses of rivaroxaban versus aspirin for prevention of recurrent venous thromboembolism Academic Article
Ulcerative Colitis Remission Status After Induction With Mesalazine Predicts Maintenance Outcomes: the MOMENTUM Trial Academic Article
Understanding Preferences for Disease-Modifying Drugs in Osteoarthritis Academic Article
Update Alert 2: Should Remdesivir Be Used for the Treatment of Patients With COVID-19? Rapid, Living Practice Points From the American College of Physicians (Version 2) Academic Article
Update on community-acquired pneumonia Conference Paper
Upstream anticoagulation for patients with ST‐elevation myocardial infarction undergoing primary percutaneous coronary intervention: Insights from the TOTAL trial Academic Article
Use of Antithrombotic Agents During Pregnancy Academic Article
Use of Inhaled Insulin in a Basal/Bolus Insulin Regimen in Type 1 Diabetic Subjects Academic Article
Use of antibiotics for the treatment of preterm parturition and prevention of neonatal morbidity: a metaanalysis Conference Paper
Use of dexamethasone and granisetron in the control of delayed emesis for patients who receive highly emetogenic chemotherapy. National Cancer Institute of Canada Clinical Trials Group. Academic Article
Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology Academic Article
Use of heparins in patients with cancer: individual participant data meta-analysis of randomised trials study protocol Academic Article
Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases Academic Article
Use of slow-release melatonin in treatment-resistant depression. Academic Article
Using the Maximum Test Statistic in the Two-Period Crossover Clinical Trial Academic Article
Vardenafil Improves Erectile Function in Men with Erectile Dysfunction Irrespective of Disease Severity and Disease Classification Academic Article
Vascular viewpoint Academic Article
Venous Thromboembolism in Older Adults: A Community-based Study Academic Article
Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia Academic Article
Venous thromboembolism prophylaxis: role of factor xa inhibition by fondaparinux. Academic Article
Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis Academic Article
Vitamin D supplementation-clarity required regarding treatment regimens and target plasma levels Academic Article
Vitamin K to reverse the anticoagulant effect of vitamin K antagonists: can you teach an old dog new tricks? Academic Article
Warfarin Maintenance Dosing Patterns in Clinical Practice Academic Article
Weekly Cyclophosphamide and Alternate-Day Prednisone: An Effective, Convenient, and Well-Tolerated Oral Treatment for Relapsed Multiple Myeloma After Autologous Stem Cell Transplantation Academic Article
Weekly Intravenous Methotrexate with Folinic Acid for Nonmetastatic Gestational Trophoblastic Neoplasia Academic Article
Weight-adjusted Intravenous Reslizumab in Severe Asthma with Inadequate Response to Fixed-Dose Subcutaneous Mepolizumab Academic Article
Weight‐adjusted tinzaparin for the prevention of venous thromboembolism after bariatric surgery Academic Article
When the Rubber Meets the Road: Adherence and Persistence with Non–Vitamin K Antagonist Oral Anticoagulants and Old Oral Anticoagulants in the Real World—A Problem or A Myth ? Academic Article
Will eradication of Helicobacter pylori infection influence the risk of gastric cancer? Academic Article
World Health Organization treatment guidelines for drug-resistant tuberculosis, 2016 update Academic Article
Xarelto plus Acetylsalicylic acid: Treatment patterns and Outcomes in patients with Atherosclerosis (XATOA): Rationale and design of a prospective registry study to assess rivaroxaban 2.5 mg twice daily plus aspirin for prevention of atherothrombotic events in coronary artery disease, peripheral artery disease, or both Academic Article
Zomepirac as an analgesic premedication: A comparison of three dosage regimens Academic Article
[Functional dyspepsia: approaches to Helicobacter pylori eradication therapy]. Academic Article

Drug Administration Schedule Concept

Vocabulary Service

Overview

subject area of