Journal article
Tirapazamine with cisplatin in patients with advanced non-small-cell lung cancer: a phase II study.
Abstract
PURPOSE: A phase II study was conducted to evaluate the safety and efficacy of tirapazamine combined with cisplatin for the treatment of patients with advanced non-small-cell lung cancer (NSCLC).
PATIENTS AND METHODS: Forty-four patients with stage IIIB/IV NSCLC were treated with a combination of tirapazamine and cisplatin. Patients received tirapazamine 260 mg/m2 administered intravenously over 2 hours, followed 1 hour later by cisplatin 75 …
Authors
Treat J; Johnson E; Langer C; Belani C; Haynes B; Greenberg R; Rodriquez R; Drobins P; Miller W; Meehan L
Journal
Journal of Clinical Oncology, Vol. 16, No. 11, pp. 3524–3527
Publisher
American Society of Clinical Oncology (ASCO)
Publication Date
November 1998
DOI
10.1200/jco.1998.16.11.3524
ISSN
0732-183X