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Comparison of Dabigatran and Warfarin in Patients...
Journal article

Comparison of Dabigatran and Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease

Abstract

BACKGROUND: The RE-LY trial (Randomized Evaluation of Long-Term Anticoagulant Therapy) compared dabigatran 150 and 110 mg twice daily with warfarin in 18 113 patients with atrial fibrillation. Those with prosthetic heart valves, significant mitral stenosis, and valvular heart disease (VHD) requiring intervention were excluded. Others with VHD were included. METHODS: This is a post hoc analysis of the RE-LY trial.

Authors

Ezekowitz MD; Nagarakanti R; Noack H; Brueckmann M; Litherland C; Jacobs M; Clemens A; Reilly PA; Connolly SJ; Yusuf S

Journal

Circulation, Vol. 134, No. 8, pp. 589–598

Publisher

Wolters Kluwer

Publication Date

August 23, 2016

DOI

10.1161/circulationaha.115.020950

ISSN

0009-7322