Journal article
7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial
Abstract
BackgroundShorter-duration antibiotic treatment is sufficient for a range of bacterial infections, but has not been adequately studied for bloodstream infections. Our systematic review, survey, and observational study indicated equipoise for a trial of 7 versus 14 days of antibiotic treatment for bloodstream infections; a pilot randomized clinical trial (RCT) was a necessary next step to assess feasibility of a larger trial.MethodsWe conducted …
Authors
Daneman N; Rishu AH; Pinto R; Aslanian P; Bagshaw SM; Carignan A; Charbonney E; Coburn B; Cook DJ; Detsky ME
Journal
Trials, Vol. 19, No. 1,
Publisher
Springer Nature
Publication Date
12 2018
DOI
10.1186/s13063-018-2474-1
ISSN
1468-6708