Journal article
Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty
Abstract
BACKGROUND: Moderate to severe pain after total knee arthroplasty often interferes with postoperative rehabilitation and delays discharge from hospital. The present study examined the effects of a four-day postoperative gabapentin (GBP) regimen versus placebo on opioid consumption, pain scores and knee flexion, as well as adverse effects, after total knee arthroplasty.
METHODS: After obtaining research ethics board approval and informed …
Authors
Clarke H; Pereira S; Kennedy D; Gilron I; Katz J; Gollish J; Kay J
Journal
Pain Research and Management, Vol. 14, No. 3, pp. 217–222
Publisher
Wiley
Publication Date
January 2009
DOI
10.1155/2009/930609
ISSN
1203-6765
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AgedAminesAnalgesicsAnalysis of VarianceAnti-Inflammatory Agents, Non-SteroidalArthroplasty, Replacement, KneeCelecoxibCyclohexanecarboxylic AcidsDrug Administration ScheduleFemaleGabapentinHumansMaleMiddle AgedMorphinePain, PostoperativePyrazolesRecovery of FunctionSingle-Blind MethodSulfonamidesTime Factorsgamma-Aminobutyric Acid