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The Thrombogenic Effect of Anticancer Drug Therapy...
Journal article

The Thrombogenic Effect of Anticancer Drug Therapy in Women with Stage II Breast Cancer

Abstract

Thromboembolic disease has long been recognized as a complication of cancer. Recent reports have suggested that drugs used in the treatment of cancer, including chemotherapeutic agents and hormones, may contribute to this risk, but it has not been possible to separate the effect of these drugs from that of the cancer. We performed a randomized trial comparing 12 weeks of chemohormonal therapy (using cyclophosphamide, methotrexate, fluorouracil, …

Authors

Levine MN; Gent M; Hirsh J; Arnold A; Goodyear MD; Hryniuk W; De Pauw S

Journal

The New England Journal of Medicine, Vol. 318, No. 7, pp. 404–407

Publisher

Massachusetts Medical Society

Publication Date

February 18, 1988

DOI

10.1056/nejm198802183180703

ISSN

0028-4793