Journal article
Time to maximum effect of lansoprazole on gastric pH in normal male volunteers
Abstract
BACKGROUND: The time to maximum inhibition of gastric acidity resulting from repeated oral dosing with lansoprazole 30 mg daily for 7 days was studied in nine healthy male volunteers.
METHODS: Twenty-four hour intragastric pH monitoring was performed before treatment and on days 1, 3, 5 and 7 of dosing with lansoprazole. Blood samples were taken for the estimation of plasma lansoprazole concentrations.
Authors
BELL NJV; HUNT RH
Journal
Alimentary Pharmacology & Therapeutics, Vol. 10, No. 6, pp. 897–904
Publisher
Wiley
Publication Date
October 1996
DOI
10.1046/j.1365-2036.1996.103242000.x
ISSN
0269-2813