Journal article
Ibogaine interferes with motivational and somatic effects of naloxone-precipitated withdrawal from acutely administered morphine
Abstract
It has been reported that ibogaine interferes with somatic withdrawal reactions in rats chronically treated with morphine. The present experiments demonstrated that ibogaine also interferes with motivational withdrawal reactions and somatic withdrawal reactions in rats treated with morphine on only two occasions. On each of two conditioning trials, naloxone was administered 24 h following an injection of morphine. Four hours prior to each …
Authors
Parker LA; Burton P; McDonald RV; Kim JA; Siegel S
Journal
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 26, No. 2, pp. 293–297
Publisher
Elsevier
Publication Date
February 2002
DOI
10.1016/s0278-5846(01)00268-8
ISSN
0278-5846