Journal article
Effect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Failure
Abstract
Importance: Short-term infusions of single vasodilators, usually given in a fixed dose, have not improved outcomes in patients with acute heart failure (AHF).
Objective: To evaluate the effect of a strategy that emphasized early intensive and sustained vasodilation using individualized up-titrated doses of established vasodilators in patients with AHF.
Authors
Kozhuharov N; Goudev A; Flores D; Maeder MT; Walter J; Shrestha S; Gualandro DM; de Oliveira Junior MT; Sabti Z; Müller B
Journal
JAMA: The Journal of the American Medical Association, Vol. 322, No. 23, pp. 2292–2302
Publisher
American Medical Association (AMA)
Publication Date
December 17, 2019
DOI
10.1001/jama.2019.18598
ISSN
0098-7484