Journal article
Single Daily Dosing of Aminoglycosides in Immunocompromised Adults: A Systematic Review
Abstract
We examined the efficacy and toxicity of single daily dosing (SDD) of aminoglycosides for febrile, immunocompromised adults by systematically reviewing four randomized, controlled trials of SDD vs. standard dosing regimens. We assessed the methodological quality of each study and extracted data pertaining to efficacy and toxicity outcomes. Pooled risk ratios for the efficacy outcomes were bacteriologic cure, 1.00 (95% confidence interval [CI], …
Authors
Hatala R; Dinh TT; Cook DJ
Journal
Clinical Infectious Diseases, Vol. 24, No. 5, pp. 810–815
Publisher
Oxford University Press (OUP)
Publication Date
May 1, 1997
DOI
10.1093/clinids/24.5.810
ISSN
1058-4838