Journal article
Alpha-Blocker Use and the Risk of Hypotension and Hypotension-Related Clinical Events in Women of Advanced Age
Abstract
Alpha-blockers (ABs) are commonly prescribed as part of a multidrug regimen in the management of hypertension. We set out to assess the risk of hypotension and related adverse events with AB use compared with other blood pressure (BP) lowering drugs using a population-based, retrospective cohort study of women (≥66 years) between 1995 and 2015 in Ontario, Canada. Cox proportional hazards examined the association of AB use and hypotension and …
Authors
Hiremath S; Ruzicka M; Petrcich W; McCallum MK; Hundemer GL; Tanuseputro P; Manuel D; Burns K; Edwards C; Bugeja A
Journal
Hypertension, Vol. 74, No. 3, pp. 645–651
Publisher
Wolters Kluwer
Publication Date
September 2019
DOI
10.1161/hypertensionaha.119.13289
ISSN
0194-911X
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Accidental FallsAdrenergic alpha-AntagonistsAge FactorsAgedAged, 80 and overAntihypertensive AgentsCanadaCohort StudiesDose-Response Relationship, DrugDrug Administration ScheduleFemaleFractures, BoneGeriatric AssessmentHumansHypertensionHypotensionIncidencePrognosisPropensity ScoreProportional Hazards ModelsRetrospective StudiesRisk AssessmentSyncopeTreatment Outcome