Journal article
Denosumab Treatment in Postmenopausal Women with Osteoporosis Does Not Interfere with Fracture-Healing
Abstract
BACKGROUND: Fracture is the major complication of osteoporosis, and it allows the identification of individuals needing medical intervention for osteoporosis. After nonvertebral fracture, patients often do not receive osteoporosis medical treatment despite evidence that this treatment reduces the risk of subsequent fracture. In this pre planned analysis of the results of the three-year, placebo-controlled FREEDOM trial, we evaluated the effect …
Authors
Adami S; Libanati C; Boonen S; Cummings SR; Ho P-R; Wang A; Siris E; Lane J; Adachi JD; Bhandari M
Journal
Journal of Bone and Joint Surgery, Vol. 94, No. 23, pp. 2113–2119
Publisher
Wolters Kluwer
Publication Date
December 5, 2012
DOI
10.2106/jbjs.k.00774
ISSN
0021-9355
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Absorptiometry, PhotonAgedAged, 80 and overAntibodies, Monoclonal, HumanizedBone DensityBone Density Conservation AgentsChi-Square DistributionDenosumabDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesFracture Fixation, InternalFracture HealingFractures, SpontaneousHumansInjections, SubcutaneousMiddle AgedOsteoporosis, PostmenopausalProspective StudiesReference ValuesRisk AssessmentSpinal FracturesTreatment Outcome