Journal article
The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review
Abstract
BACKGROUND: Cholangiocarcinoma and gallbladder cancer are difficult to treat curatively. The treatment of choice is surgery, dependent on detection at a resectable stage. No chemotherapy or radiotherapy options have shown substantial activity. Gemcitabine has demonstrated response in similar cancers. Considering the lack of treatment options for cholangiocarcinoma and gallbladder cancer, a systematic review of the evidence on gemcitabine use …
Authors
Dingle BH; Rumble RB; Brouwers MC
Journal
Canadian Journal of Gastroenterology and Hepatology, Vol. 19, No. 12, pp. 711–716
Publisher
Hindawi
Publication Date
2005
DOI
10.1155/2005/565479
ISSN
2291-2789
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Antimetabolites, AntineoplasticAntineoplastic Combined Chemotherapy ProtocolsCholangiocarcinomaClinical Trials, Phase II as TopicDeoxycytidineDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesGallbladder NeoplasmsHumansMaleMaximum Tolerated DoseNeoplasm InvasivenessNeoplasm StagingSurvival AnalysisTreatment OutcomeGemcitabine